Patents by Inventor Kiyofumi YAMANISHI

Kiyofumi YAMANISHI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Atopic dermatitis model animal and use thereof
    Patent number: 9949465
    Abstract: The present invention provides a transgenic non-human mammal retaining, in a specifically expressible state, a DNA encoding IL-33 in the skin, and having one or more features selected from the group consisting of (1) spontaneous onset of dermatitis, (2) increase in the number of inflammatory cells, (3) increase in total IgE concentration, histamine concentration, cytokine concentration and/or chemokine concentration, and (4) increase in scratching time, under SPF (specific pathogen free) breeding conditions, as compared to a corresponding non-transgenic non-human mammal, and the like.
    Type: Grant
    Filed: April 30, 2014
    Date of Patent: April 24, 2018
    Assignees: Hyogo College of Medicine, Mie University
    Inventors: Kiyofumi Yamanishi, Hitoshi Mizutani, Yasutomo Imai, Tomohiro Yoshimoto, Kenji Nakanishi
  • ATOPIC DERMATITIS MODEL ANIMAL AND USE THEREOF
    Publication number: 20160057978
    Abstract: The present invention provides a transgenic non-human mammal retaining, in a specifically expressible state, a DNA encoding IL-33 in the skin, and having one or more features selected from the group consisting of (1) spontaneous onset of dermatitis, (2) increase in the number of inflammatory cells, (3) increase in total IgE concentration, histamine concentration, cytokine concentration and/or chemokine concentration, and (4) increase in scratching time, under SPF (specific pathogen free) breeding conditions, as compared to a corresponding non-transgenic non-human mammal, and the like.
    Type: Application
    Filed: April 30, 2014
    Publication date: March 3, 2016
    Inventors: Kiyofumi YAMANISHI, Hitoshi MIZUTANI, Yasutomo IMAI, Tomohiro YOSHIMOTO, Kenji NAKANISHI