Patents by Inventor Kiyohito Yagi

Kiyohito Yagi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-claudin-2 monoclonal antibody
    Patent number: 11078271
    Abstract: An object of the present invention is to provide a monoclonal antibody that recognizes an extracellular region of Claudin-2. A monoclonal antibody that specifically binds to an extracellular region of Claudin-2.
    Type: Grant
    Filed: December 25, 2017
    Date of Patent: August 3, 2021
    Assignee: Osaka University
    Inventors: Masuo Kondoh, Kiyohito Yagi, Akihiro Watari, Masayoshi Fukasawa, Minoru Tada, Jun Kunisawa
  • Anti-CLDN-5 antibody, and drug containing said antibody
    Patent number: 11053313
    Abstract: An object of the present invention is to provide a novel molecule which has high specificity to CLDN-5 and recognizes an extracellular domain of CLDN-5. The object is achieved by an antibody which specifically recognizes a three-dimensional structure or a primary structure of an extracellular domain of a Claudin-5 protein.
    Type: Grant
    Filed: April 26, 2018
    Date of Patent: July 6, 2021
    Assignees: OSAKA UNIVERSITY, NATIONAL UNIVERSITY CORPORATION EHIME UNIVERSITY, FUJIFILM WAKO PURE CHEMICAL CORPORATION
    Inventors: Masuo Kondoh, Kiyohito Yagi, Takefumi Doi, Yoshiaki Okada, Yosuke Hashimoto, Tatsuya Sawasaki, Hiroyuki Takeda, Kohki Endo, Maki Tamura
  • Claudin 5 antibody, and medicine containing said antibody
    Patent number: 10882906
    Abstract: Provided is a novel technique for controlling the blood-brain barrier. An antibody whose epitope is a region within an extracellular domain of Claudin 5 protein.
    Type: Grant
    Filed: December 4, 2017
    Date of Patent: January 5, 2021
    Assignee: OSAKA UNIVERSITY
    Inventors: Yoshiaki Okada, Masuo Kondoh, Yosuke Hashimoto, Keisuke Shirakura, Takefumi Doi, Kiyohito Yagi, Hiroyuki Takeda, Tatsuya Sawasaki
  • Claudin 5 ANTIBODY, AND MEDICINE CONTAINING SAID ANTIBODY
    Publication number: 20200223915
    Abstract: Provided is a novel technique for controlling the blood-brain barrier. An antibody whose epitope is a region within an extracellular domain of Claudin 5 protein.
    Type: Application
    Filed: December 4, 2017
    Publication date: July 16, 2020
    Applicant: OSAKA UNIVERSITY
    Inventors: Yoshiaki OKADA, Masuo KONDOH, Yosuke HASHIMOTO, Keisuke SHIRAKURA, Takefumi DOI, Kiyohito YAGI, Hiroyuki TAKEDA, Tatsuya SAWASAKI
  • ANTI-CLDN-5 ANTIBODY, AND DRUG CONTAINING SAID ANTIBODY
    Publication number: 20200148765
    Abstract: An object of the present invention is to provide a novel molecule which has high specificity to CLDN-5 and recognizes an extracellular domain of CLDN-5. The object is achieved by an antibody which specifically recognizes a three-dimensional structure or a primary structure of an extracellular domain of a Claudin-5 protein.
    Type: Application
    Filed: April 26, 2018
    Publication date: May 14, 2020
    Applicants: OSAKA UNIVERSITY, NATIONAL UNIVERSITY CORPORATION EHIME UNIVERSITY, FUJIFILM Wako Pure Chemical Corporation
    Inventors: Masuo KONDOH, Kiyohito YAGI, Takefumi DOI, Yoshiaki OKADA, Yosuke HASHIMOTO, Tatsuya SAWASAKI, Hiroyuki TAKEDA, Kohki ENDO, Maki TAMURA
  • Anti-Claudin-2 Monoclonal Antibody
    Publication number: 20200140542
    Abstract: An object of the present invention is to provide a monoclonal antibody that recognizes an extracellular region of Claudin-2. A monoclonal antibody that specifically binds to an extracellular region of Claudin-2.
    Type: Application
    Filed: December 25, 2017
    Publication date: May 7, 2020
    Applicant: Osaka University
    Inventors: Masuo Kondoh, Kiyohito Yagi, Akihiro Watari, Masayoshi Fukasawa, Minoru Tada, Jun Kunisawa
  • SUPPORT FOR PROTEIN TRANSFER, PROTEIN TRANSFER AGENT USING THE SUPPORT, PROTEIN TRANSFER METHOD, CELL HAVING PROTEIN TRANSFERRED THEREINTO AND METHOD OF PRODUCING THE SAME
    Publication number: 20100267627
    Abstract: A protein introduction method with which protein can be introduced into cells with excellent safety is provided. A target protein is supported on a carrier for protein introduction that is made from a clay mineral, and by adding this to cells it is possible to introduce the target protein into the cells. The clay mineral is preferably a layered clay mineral, and as the clay mineral it is possible to use montmorillonite, vermiculite, and illite, for example.
    Type: Application
    Filed: June 30, 2010
    Publication date: October 21, 2010
    Applicant: MEIJI DAIRIES CORPORATION
    Inventors: Kiyohito YAGI, Masaya KAWASE, Masashi YAMADA, Hiroto SUZUKI, Kohsuke KINO, Yoshio OHYAMA, Kazumitsu OHTSUBO
  • Support For Protein Transfer, Protein Transfer Agent Using the Support, Protein Transfer Method, Cell Having Protein Transferred Thereinto and Method of Producing the Same
    Publication number: 20080182786
    Abstract: A protein introduction method with which protein can be introduced into cells with excellent safety is provided. A target protein is supported on a carrier for protein introduction that is made from a clay mineral, and by adding this to cells it is possible to introduce the target protein into the cells. The clay mineral is preferably a layered clay mineral, and as the clay mineral it is possible to use montmorillonite, vermiculite, and illite, for example.
    Type: Application
    Filed: February 7, 2006
    Publication date: July 31, 2008
    Applicant: Meiji Dairies Corporation
    Inventors: Kiyohito Yagi, Masaya Kawase, Masashi Yamada, Hiroto Suzuki, Kohsuke Kino, Yoshio Ohyama, Kazumitsu Ohtsubo
  • Biosensor Utilizing Pigment-Synthesizing Gene Of A Purple Non-Sulfur Bacterium And A Method For Preparing Such A Biosensor
    Publication number: 20080044829
    Abstract: A biosensor where measurement is able to be conducted by simpler operations, cost is less expensive and specific chemical substance is able to be visually detected is provided. In accordance with the present invention, there is provided a biosensor for the detection of a specific chemical substance, characterized in that it comprises a recombinant purple non-sulfur bacterium wherein sensor vector is introduced into a pigment variant of a purple non-sulfur bacterium being deficient in gene coding for a spheroidene monooxygenase enzyme, and that the sensor vector is a sensor vector where inductive promoter showing a specific response to a specific chemical substance is connected in an operable manner to the upstream region of gene coding for the spheroidene monooxygenase enzyme.
    Type: Application
    Filed: August 22, 2005
    Publication date: February 21, 2008
    Applicants: THE KANSAI ELECTRIC POWER CO., INC., OSAKA UNIVERSITY
    Inventors: Kiyohito Yagi, Masaya Kawase, Isamu Maeda, Hidenori Yamashiro, Hitoshi Miyasaka
  • Process for producing hydrogen by alga in alternating light/dark cycle and environmental aerobic/microaerobic conditions
    Patent number: 4532210
    Abstract: Hydrogen is biologically, effectively produced by an alga in an alternating light/dark cycle which comprises alternating a step for cultivating the alga in water under aerobic conditions in the presence of light to accumulate photosynthetic products in the alga and a step for cultivating the alga in water under microaerobic conditions in the dark to decompose accumulated material by photosynthesis to evolve hydrogen.
    Type: Grant
    Filed: September 27, 1982
    Date of Patent: July 30, 1985
    Inventors: Yoshiharu Miura, Kazuhisa Miyamoto, Kiyohito Yagi