Patents by Inventor Kiyoko KOHAMA

Kiyoko KOHAMA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10775393
    Abstract: Disclosed is a reagent for prothrombin time measurement, wherein the reagent contains a liposome composition containing a first liposome having a phospholipid layer, a second liposome having a phospholipid layer of a different composition from that of the first liposome, and tissue factor, wherein the tissue factor is associated with the phospholipid layer of at least one of the first liposome and the second liposome; the first liposome contains a phosphatidylcholine compound, a phosphatidylethanolamine compound, and a phosphatidylserine compound; and the second liposome contains at least one phospholipid selected from the group consisting of a phosphatidylcholine compound and a phosphatidylethanolamine compound.
    Type: Grant
    Filed: March 24, 2017
    Date of Patent: September 15, 2020
    Assignee: SYSMEX CORPORATION
    Inventors: Yusuke Tanaka, Takahiko Bando, Kiyoko Kohama, Haruki Yamaguchi
  • Patent number: 10640805
    Abstract: Disclosed is a reagent for prothrombin time measurement, containing a tissue factor and a surfactant, wherein the value of formula (I), which is represented by (surfactant amount (?mol))/(total protein amount (?g)), is 0.013 to 0.05 ?mol/?g.
    Type: Grant
    Filed: March 29, 2017
    Date of Patent: May 5, 2020
    Assignee: SYSMEX CORPORATION
    Inventors: Masato Michishita, Takahiko Bando, Yusuke Tanaka, Kiyoko Kohama
  • Publication number: 20170285046
    Abstract: Disclosed is a reagent for prothrombin time measurement, wherein the reagent contains a liposome composition containing a first liposome having a phospholipid layer, a second liposome having a phospholipid layer of a different composition from that of the first liposome, and tissue factor, wherein the tissue factor is associated with the phospholipid layer of at least one of the first liposome and the second liposome; the first liposome contains a phosphatidylcholine compound, a phosphatidylethanolamine compound, and a phosphatidylserine compound; and the second liposome contains at least one phospholipid selected from the group consisting of a phosphatidylcholine compound and a phosphatidylethanolamine compound.
    Type: Application
    Filed: March 24, 2017
    Publication date: October 5, 2017
    Applicant: SYSMEX CORPORATION
    Inventors: Yusuke TANAKA, Takahiko BANDO, Kiyoko KOHAMA, Haruki YAMAGUCHI
  • Publication number: 20170283853
    Abstract: Disclosed is a reagent for prothrombin time measurement, containing a tissue factor and a surfactant, wherein the value of formula (I), which is represented by (surfactant amount (?mol))/(total protein amount (?g)), is 0.013 to 0.05 ?mol/?g.
    Type: Application
    Filed: March 29, 2017
    Publication date: October 5, 2017
    Applicant: SYSMEX CORPORATION
    Inventors: Masato MICHISHITA, Takahiko BANDO, Yusuke TANAKA, Kiyoko KOHAMA