Patents by Inventor Kiyomoto Ogasawara

Kiyomoto Ogasawara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR PREDICTING SENSITIVITY OF CANCER CELL TO GPX4 INHIBITOR
    Publication number: 20230204589
    Abstract: Provided are a cancer therapeutic drug comprising a compound which inhibits GPX4 as an active ingredient, the cancer therapeutic drug treating cancer containing a cancer cell having a suppressed function of a SWI/SNF complex factor detected; and a method for predicting sensitivity of a cancer cell to a GPX4 inhibitor, the method comprising the step of predicting a cancer cell having a suppressed function of a SWI/SNF complex factor detected in the cancer cell, as having sensitivity to the GPX4 inhibitor.
    Type: Application
    Filed: December 25, 2020
    Publication date: June 29, 2023
    Applicant: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Kiyomoto Ogasawara, Keisuke Hashimoto, Kenji Kashima, Hiroshi Sakamoto
  • METHOD FOR PREDICTING SENSITIVITY OF CANCER CELL TO HELICASE INHIBITOR
    Publication number: 20220389516
    Abstract: Provided is a method for predicting sensitivity of a cancer cell to a helicase inhibitor, the method comprising the step of: predicting a cancer cell having at least one mutation detected selected from the first group consisting of TTK mutation and RAD 50 mutation, as having sensitivity to a helicase inhibitor, or predicting a cancer cell having at least one mutation detected selected from the second group consisting of RAD 50 mutation, MRE 11 mutation, NBN mutation, DNA 2 mutation and RBBP 8 mutation, as having sensitivity to a helicase inhibitor.
    Type: Application
    Filed: November 20, 2020
    Publication date: December 8, 2022
    Applicant: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Hiroshi Sakamoto, Kenji Kashima, Kiyomoto Ogasawara, Yuki Ohte, Mayumi Soga