Patents by Inventor Kiyoshi H. Takeuchi

Kiyoshi H. Takeuchi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Neural calcium-activated neutral proteinase inhibitors
    Patent number: 5629165
    Abstract: This invention is directed to two highly purified neural calcium-activated neutral proteinase (CANP or calpain) inhibitors, known as high molecular weight calpastatin (HMWC) and low molecular weight calpastatin (LMWC). The invention also relates to recombinant DNA molecules which code for, and antibodies which bind to these proteins. The present invention is further directed to the use of these calpastatin proteins.
    Type: Grant
    Filed: February 25, 1994
    Date of Patent: May 13, 1997
    Assignee: The McLean Hospital Corporation
    Inventors: Ralph A. Nixon, Kiyoshi H. Takeuchi
  • Neural calcium-activated neutral proteinase inhibitors
    Patent number: 5340922
    Abstract: This invention is directed to two highly purified neural calcium-activated neutral proteinase (CANP or calpain) inhibitors, known as high molecular weight calpastatin (HMWC) and low molecular weight calpastatin (LMWC). The invention also relates to recombinant DNA molecules which code for, and antibodies which bind to these proteins. The present invention is further directed to the use of these calpastatin proteins.
    Type: Grant
    Filed: July 25, 1991
    Date of Patent: August 23, 1994
    Assignee: The McLean Hospital Corporation
    Inventors: Ralph A. Nixon, Kiyoshi H. Takeuchi