Abstract: This invention relates to a compound with EP4 antagonistic activity, or a pharmaceutically acceptable salt with EP4 receptor antagonistic activities, which is useful in the treatment of immune disease or allergy. This invention also relates to a compound of formula (I), (II), (III), (IV), (Va) or (Vb), or a pharmaceutically acceptable salt thereof with EP4 receptor antagonistic activities, which is useful in the treatment of immune disease or allergy. This invention also relates to a pharmaceutical composition for the treatment of immune disease or allergy which comprises a therapeutically effective amount of a compound of formula (I), (II), (III), (IV), (Va) or (Vb), or a pharmaceutically acceptable salt thereof.

Abstract: This invention relates to a compound with EP4 antagonistic activity, or a pharmaceutically acceptable salt with EP4 receptor antagonistic activities, which is useful in the treatment of immune disease or allergy. This invention also relates to a compound of formula (I), (II), (III), (IV), (Va) or (Vb), or a pharmaceutically acceptable salt thereof with EP4 receptor antagonistic activities, which is useful in the treatment of immune disease or allergy. This invention also relates to a pharmaceutical composition for the treatment of immune disease or allergy which comprises a therapeutically effective amount of a compound of formula (I), (II), (III), (IV), (Va) or (Vb), or a pharmaceutically acceptable salt thereof.

Abstract: A heating device includes a main body with an opening, a magnetron for generating electromagnetic waves for heating, a door for putting in and taking out an object to be heated, a reader, and a barrier. The magnetron emits electromagnetic waves into the main body. The door covers the opening of the main body. The reader reads information contained in a wireless IC tag attached to the object to be heated. The barrier acts a shield for the reader from the electromagnetic waves emitted by the magnetron when the door is closed, and the shield is broken when the door is opened.

Abstract: A communication system for providing information of a medical doctor's questions to patients includes a medical doctor terminal apparatus, a patient terminal apparatus, and a database server apparatus for storing question sets for the medical doctor's questions to patients, where the medical doctor terminal apparatus, patient terminal apparatus and database server apparatus are connected through a communication network. The patient terminal apparatus generates question programs for making inquiries about the medical doctor's questions to patients in accordance with the question sets received from the database server apparatus, displays the questions for the medical doctor's questions to patients by execution of the generated question programs, enters answer data to the displayed questions, transmits the entered answer data to the database server apparatus, and stores the transmitted answer data in the database server apparatus.

Abstract: A communication system for information of medical doctor's questions to patients includes a terminal apparatus for medical doctor, a terminal apparatus for patient, and a database server apparatus for storing question sets for medical doctor's questions to patients, which are connected through a communication network. The terminal apparatus for patient generates question programs for making inquiries about medical doctor's questions to patients in accordance with the question sets received from the database server apparatus, displays the questions for medical doctor's questions to patients by execution of the generated question programs, enters answer data to the displayed questions, transmits the entered answer data to the database server apparatus, and stores the transmitted answer data in the database server apparatus. The terminal apparatus for medical doctor receives the stored answer data by accessing the database server apparatus, and displays the received answer data thereon.

Abstract: A heating device includes a main body with an opening, a magnetron for generating electromagnetic waves for heating, a door for putting in and taking out an object to be heated, a reader, and a barrier. The magnetron emits electromagnetic waves into the main body. The door covers the opening of the main body. The reader reads information contained in a wireless IC tag attached to the object to be heated. The barrier acts a shield for the reader from the electromagnetic waves emitted by the magnetron when the door is closed, and the shield is broken when the door is opened.

Abstract: It is an object of the present invention to desirably induce a user's gaze onto a keyboard or numeral buttons when data is directly inputted from the keyboard or the numeral buttons. In order to attain this object, a data input apparatus 10 according to the present invention includes: a first operating means 1 for directly inputting at least either of numerical data and character data; a second operating means 2 for executing an operation except a direct input of numerical data and character data; and an inducing means 5 for inducing a user's gaze onto the first operating means by having a blinking operation accompanied when a data input is started by the first operating means. When a data input is started by the first operating means 1, the inducing means 5 blinks on and off an induction mark 3c which expresses the shape of the first operating means 1 and the direction in which the first operating means 1 is located.

Abstract: An insurance descriptions adjusting system for properly setting an insurance premium. The system comprises an insurance descriptions adjusting method and device, a status data acquiring terminal device, an advice responding terminal device, and advice device, an insurance descriptions adjusting program, a status data acquiring program, an advice responding program, an advice program, and a computer-readable recording medium for recording those programs. Insurance descriptions determined based on a status data describing a state of an insured object are adjusted by using a level of enthusiasm shown by an insurance contractor towards the reacquisition of the status data and a level of enthusiasm shown by the insurance contractor in reducing the risk of an insured object. Accordingly, a proper insurance premium is set for an insured object whose future risks are likely to go lower.

Abstract: A themometer for measuring a body temperature by using infrared rays and on the basis of a measuring method in which a measurement error fluctuates depending upon the length of the measuring time including computation time. The measuring time is calculated on the basis of a required measurement error, so that a temperature can be measured in a suitable time corresponding to a required allowable error. A probe is formed of a porous structure so as to improve the heat insulating effect thereof, and an auxiliary adapter is provided to permit the thermometer to be fitted better in the earhole in spite of an individual difference in size thereof with the function of reporting a relative ovulation date based on a desired delivery date also incorporated in the themometer.

Abstract: A medical checkup network system comprises a patient terminal for measuring the biodata of each patient including a blood pressure and a body temperature, a doctor terminal for allowing the medical staff to view the biodata of each patient for diagnosis and enter a medical support data including a schedule data and an advice data, and a center server for storing the data received from the those terminals. They are connected to each other over a communication network such as the Internet. In the system, the biodata of each patient stored in the center server can be registered and viewed by any of the patient terminal, the doctor terminal, the patient and the medical staff which have been registered in the center server. The system can thus protect the privacy of each patient about the biodata and permit the biodata of each patient to be shared by two or more members of the medical staff.

Abstract: A radiation thermometer measures temperature of the eardrum. The thermometer comprises a signal processor for calculating a temperature from an output of a light receptor, which receives only the infrared rays radiated directly from the eardrum and/or vicinity of it, and a notification system for notifying the temperature resulted from the calculation. Since the structure does not receive an influence of any radiant heats from other than those of the eardrum and/or vicinity of it, temperature change of a probe does not become a factor of measuring errors, so as to offer an accurate measurement of temperatures.

Abstract: A document data filing apparatus automatically selects attribute values indicating visual features of a desired document from the code data of document data inputted. The attribute value generation unit generates attribute values indicating visual features of the document data inputted as coded data from the document data input unit. At this point, the presence or absence of dot data and specific words and characters are judged. The document data storage unit stores the document data in association with its attribute for retrieval. The attribute value designation unit makes an operator designate the attribute value as retrieval key to the document data to be retrieved The readout unit reads the document data corresponding to the designated attribute value from the document data storage unit. The display unit displays the document data. The retrieving technique is applied to a word processor.

Abstract: Disclosed is a method for simulating an operation of an event driven logic circuit in response to changes of the signal status of each terminal of all the elements in the logical circuit, based on event data each containing event time indicating when the signal status has changed, status change indicating how the status has changed, an element identifier identifying the element, and a terminal identifier identifying the terminal, the method comprising a simulation time output step for outputting data indicating simulation time which is continuously counted up; a first selection step for selecting the event data whose event time is equal to the simulation time; a second selection step for selecting the event data whose event time is earliest among event data present for all the input terminals of the element corresponding to the event data; a simulation step for generating new event data depending on a change of the signal status of the output terminal of the element corresponding to the event data, based on t

Abstract: Determination of an operation of a logic circuit is usually called logic simulation. The logic simulation in which changes in signal status at input terminals and output terminals of an element in the logic circuit to be simulated are represented by events and the signal status at the output terminal is calculated only for the element in which the event has occurred at the input terminal thereof, is called an event driven logic simulation. In the event driven logic simulation, a current time is used to decide and extract the event to be processed. In the prior art apparatus, the decision and extraction are interrupted when the current time is updated. In the present invention, identifiers (colors) are imparted to the events to group the events. The current time is updated when the event having a special color is not present. Thus, a simulation speed in the event driven logic simulation method and apparatus is improved.

Abstract: Determining the operation of a logic circuit through calculation is generally called logic simulation. Especially, in event driven type logic simulation, signal status changes at input and output terminals of an element of the logic circuit are deemed as events and only for an element in which an event occurs at its input terminal, the signal status at its output terminal is calculated. In the event driven type logic simulation, a series of signal status changes externally applied to the logic circuit is stored, as injection events, in a memory of a logic simulation apparatus. If injection events are all stored in the memory before execution of the simulation or injection events are stored in the memory by temporarily stopping the simulation after start thereof, most of memory capacity is consumed by the injection events or simulation speed is degraded.