Patents by Inventor Kiyotaka Fukamachi
Kiyotaka Fukamachi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20210393942Abstract: A system for treating a patient with a heart condition includes an atrial assist device (AAD) configured to be positioned in the patients heart to pump blood from an atrium of the patients heart into a ventricle associated with the atrium. The system also includes a controller operatively connected to the AAD and being configured to control the AAD to pump blood from the atrium of the patients heart into the ventricle associated with the atrium.Type: ApplicationFiled: October 15, 2019Publication date: December 23, 2021Inventors: Kiyotaka Fukamachi, Jamshid Karimov, David J. Horvath, Randall C. Starling, Barry Kuban
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Patent number: 11191886Abstract: A device for minimizing obstruction in a medical device that carries fluids includes a housing defining a channel configured to receive and secure a section of the medical device such that the section of the medical device extends coaxially with a central longitudinal axis of the channel. The device also includes components supported in the housing, including a motor, wherein the components are configured to be operated to impart motion to the housing and the attached medical device. The motion is configured to produce oscillatory motion of a frequency sufficient to concentrate shear stresses in a fluid boundary layer adjacent an inner wall of the medical device. The housing and the components supported in the housing are configured and arranged so that a device center of mass lies along or near the longitudinal axis of the channel.Type: GrantFiled: March 2, 2018Date of Patent: December 7, 2021Assignee: THE CLEVELAND CLINIC FOUNDATIONInventors: Jamshid Karimov, Kiyotaka Fukamachi, Ray Dessoffy
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Patent number: 11172932Abstract: A hemostatic vessel band is provided. The hemostatic vessel band has a membrane. A plurality of cells extend transversely from a membrane second surface. Each of the cells has a cell chamber that is defined by the membrane second surface and a plurality of cell walls. When the hemostatic vessel band is selectively fastened circumferentially about a vessel to at least partially cover the target site. The hemostatic vessel band applies radially inward pressure to at least a portion of the vessel and at least a portion of the target site. Each cell chamber that is positioned transversely adjacent to at least a portion of the target site forms one isolation zone of a plurality of isolation zones. Each isolation zone is at least partially isolated from each of the other isolation zones and from any vessel surface adjacent to the isolation zone.Type: GrantFiled: September 8, 2017Date of Patent: November 16, 2021Assignee: THE CLEVELAND CLINIC FOUNDATIONInventors: Jamshid Karimov, Kiyotaka Fukamachi
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Patent number: 11045639Abstract: A ventricular assist device includes a housing including a pumping chamber. A stator assembly is supported in the housing. The stator assembly includes a core having a length measured along a pump axis. A rotating assembly is rotatable relative to the stator assembly about the pump axis. The rotating assembly includes an impeller positioned in the pumping chamber and a rotor magnet. The rotating assembly is movable axially along the pump axis relative to the pump housing and the stator assembly. The rotating assembly includes a rotor magnet configured and arranged such that the magnetic attraction of the rotor magnet to the core urges the rotating assembly to move axially relative to the stator assembly such that a flow regulating portion of the rotating assembly engages with a corresponding portion of the housing to block flow through the pumping chamber when the pump is at rest.Type: GrantFiled: October 28, 2016Date of Patent: June 29, 2021Assignee: THE CLEVELAND CLINIC FOUNDATIONInventors: David J. Horvath, Leonard A R. Golding, Barry D. Kuban, Kiyotaka Fukamachi
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Patent number: 10842631Abstract: Systems and methods for de-airing a cardiac chamber during cardiac surgery are provided. A catheter-based inflatable device is inserted adjacent a target area of the heart, and the frequency of inflation and deflation of the inflatable device is controlled via a remote controller to change the shape of the cardiac chamber to dislodge air bubbles from their deposition site in the cardiac chamber.Type: GrantFiled: February 23, 2018Date of Patent: November 24, 2020Assignee: THE CLEVELAND CLINIC FOUNDATIONInventors: Jamshid Karimov, Marc Gillinov, Kiyotaka Fukamachi
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Patent number: 10391285Abstract: Systems, devices and methods for minimizing or preventing catheter or other medical device occlusion. Mechanical motion is applied to the inner and outer walls of the catheter to minimize blood clots or other biological substances from obstructing the catheter and to help maintain catheter patency.Type: GrantFiled: June 11, 2014Date of Patent: August 27, 2019Assignee: THE CLEVELAND CLINIC FOUNDATIONInventors: Jamshid Karimov, Kiyotaka Fukamachi, Ray Dessoffy
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Publication number: 20180311426Abstract: A ventricular assist device includes a housing including a pumping chamber. A stator assembly is supported in the housing. The stator assembly includes a core having a length measured along a pump axis. A rotating assembly is rotatable relative to the stator assembly about the pump axis. The rotating assembly includes an impeller positioned in the pumping chamber and a rotor magnet. The rotating assembly is movable axially along the pump axis relative to the pump housing and the stator assembly. The rotating assembly includes a rotor magnet configured and arranged such that the magnetic attraction of the rotor magnet to the core urges the rotating assembly to move axially relative to the stator assembly such that a flow regulating portion of the rotating assembly engages with a corresponding portion of the housing to block flow through the pumping chamber when the pump is at rest.Type: ApplicationFiled: October 28, 2016Publication date: November 1, 2018Inventors: David J. Horvath, Leonard AR. Golding, Barry D. Kuban, Kiyotaka Fukamachi
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Publication number: 20180235759Abstract: Systems and methods for de-airing a cardiac chamber during cardiac surgery are provided. A catheter-based inflatable device is inserted adjacent a target area of the heart, and the frequency of inflation and deflation of the inflatable device is controlled via a remote controller to change the shape of the cardiac chamber to dislodge air bubbles from their deposition site in the cardiac chamber.Type: ApplicationFiled: February 23, 2018Publication date: August 23, 2018Inventors: Jamshid Karimov, Marc Gillinov, Kiyotaka Fukamachi
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Publication number: 20180185557Abstract: A device for minimizing obstruction in a medical device that carries fluids includes a housing defining a channel configured to receive and secure a section of the medical device such that the section of the medical device extends coaxially with a central longitudinal axis of the channel. The device also includes components supported in the housing, including a motor, wherein the components are configured to be operated to impart motion to the housing and the attached medical device. The motion is configured to produce oscillatory motion of a frequency sufficient to concentrate shear stresses in a fluid boundary layer adjacent an inner wall of the medical device. The housing and the components supported in the housing are configured and arranged so that a device center of mass lies along or near the longitudinal axis of the channel.Type: ApplicationFiled: March 2, 2018Publication date: July 5, 2018Inventors: Jamshid Karimov, Kiyotaka Fukamachi, Ray Dessoffy
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Publication number: 20180070949Abstract: A hemostatic vessel band is provided. The hemostatic vessel band has a membrane. A plurality of cells extend transversely from a membrane second surface. Each of the cells has a cell chamber that is defined by the membrane second surface and a plurality of cell walls. When the hemostatic vessel band is selectively fastened circumferentially about a vessel to at least partially cover the target site. The hemostatic vessel band applies radially inward pressure to at least a portion of the vessel and at least a portion of the target site. Each cell chamber that is positioned transversely adjacent to at least a portion of the target site forms one isolation zone of a plurality of isolation zones. Each isolation zone is at least partially isolated from each of the other isolation zones and from any vessel surface adjacent to the isolation zone.Type: ApplicationFiled: September 8, 2017Publication date: March 15, 2018Inventors: Jamshid Karimov, Kiyotaka Fukamachi
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Publication number: 20150305727Abstract: Systems, kits, and methods that provide direct visualization of a patient's surgical field and intracardiac structures during implantation of a mechanical circulatory support device. Kits and methods can provide for seamless implantation of such devices, which reduces the risks and time associated with mechanical circulatory support device implantation. Further, methods are provided that can avoid cardiopulmonary bypass.Type: ApplicationFiled: April 21, 2015Publication date: October 29, 2015Inventors: Jamshid Karimov, Kiyotaka Fukamachi, Nader Moazami
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Patent number: 9066653Abstract: One aspect of the present disclosure relates to a tissue imaging device that includes a catheter body, a hood, and a visualization assembly. The catheter body includes a distal end portion, a proximal end portion, and at least one lumen extending between the distal and proximal end portions. The catheter body includes at least one drainage port having a first opening and at least one infusion port having a second opening. The first and second openings are located about a lateral aspect of the catheter body. The hood projects distally from the distal end portion and is configured to self-expand into an expanded deployment state that defines an open area therein. The visualization assembly is disposed within the open area and extends distally from the distal end portion of the catheter body.Type: GrantFiled: March 8, 2013Date of Patent: June 30, 2015Assignee: The Cleveland Clinic FoundationInventors: Tomislav Mihaljevic, Shengqiang Gao, Kiyotaka Fukamachi, Mariko Kobayashi, Eugene J. Jung
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Patent number: 8983601Abstract: Treatment of heart failure in a patient by electrically modulating both the sympathetic and parasympathetic autonomic cardiac nerve fibers that innervate the patient's heart at an extravascular site in the pericardial space of the heart. The extravascular site is any suitable single location inside the chest cavity that carries both sympathetic and parasympathetic cardiac nerves such as the cardiac plexus or the pericardial transverse sinus or any two separate extravascular sites with one site carrying predominantly sympathetic cardiac nerves and the other site carrying predominantly parasympathetic cardiac nerves for electrically modulating the balance of autonomic cardiac nerve control.Type: GrantFiled: February 27, 2012Date of Patent: March 17, 2015Assignee: The Cleveland Clinic FoundationInventors: Kiyotaka Fukamachi, Alex Massiello, Mariko Kobayashi, Ray Dessoffy, Eugene Jung, Shubhayu Basu
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Publication number: 20140371725Abstract: Systems, devices and methods for minimizing or preventing catheter or other medical device occlusion. Mechanical motion is applied to the inner and outer walls of the catheter to minimize blood clots or other biological substances from obstructing the catheter and to help maintain catheter patency.Type: ApplicationFiled: June 11, 2014Publication date: December 18, 2014Inventors: Jamshid Karimov, Kiyotaka Fukamachi, Ray Dessoffy
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Publication number: 20130237817Abstract: One aspect of the present disclosure relates to a tissue imaging device that includes a catheter body, a hood, and a visualization assembly. The catheter body includes a distal end portion, a proximal end portion, and at least one lumen extending between the distal and proximal end portions. The catheter body includes at least one drainage port having a first opening and at least one infusion port having a second opening. The first and second openings are located about a lateral aspect of the catheter body. The hood projects distally from the distal end portion and is configured to self-expand into an expanded deployment state that defines an open area therein. The visualization assembly is disposed within the open area and extends distally from the distal end portion of the catheter body.Type: ApplicationFiled: March 8, 2013Publication date: September 12, 2013Applicant: THE CLEVELAND CLINIC FOUNDATIONInventors: Tomislav Mihaljevic, Shengqiang Gao, Kiyotaka Fukamachi, Mariko Kobayashi, Eugene J. Jung, JR.
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Publication number: 20120330092Abstract: A therapy delivery device for modulating cardiac function in a subject includes a counterpulsation component, an endovascular lead, and at least one electrode that is physically coupled with the endovascular lead. Each of the counterpulsation component and the endovascular lead includes a proximal end and a distal end. The proximal end of the endovascular lead is physically connected to the distal end of the counterpulsation component.Type: ApplicationFiled: June 18, 2012Publication date: December 27, 2012Inventors: Akira Shiose, Kiyotaka Fukamachi, Alex Massiello
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Publication number: 20120221072Abstract: Treatment of heart failure in a patient by electrically modulating both the sympathetic and parasympathetic autonomic cardiac nerve fibers that innervate the patient's heart at an extravascular site in the pericardial space of the heart. The extravascular site is any suitable single location inside the chest cavity that carries both sympathetic and parasympathetic cardiac nerves such as the cardiac plexus or the pericardial transverse sinus or any two separate extravascular sites with one site carrying predominantly sympathetic cardiac nerves and the other site carrying predominantly parasympathetic cardiac nerves for electrically modulating the balance of autonomic cardiac nerve control.Type: ApplicationFiled: February 27, 2012Publication date: August 30, 2012Applicant: THE CLEVELAND CLINIC FOUNDATIONInventors: Kiyotaka FUKAMACHI, Alex MASSIELLO, Mariko KOBAYASHI, Ray DESSOFFY, Eugene JUNG, Shubhayu BASU
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Patent number: 8207262Abstract: A dihydroxyphenyl cross-linked macromolecular network is provided that is useful in artificial tissue and tissue engineering applications, particularly to provide a synthetic macromolecular network for a wide variety of tissue types. In particular, artificial or synthetic cartilage, vocal cord material, vitreous material, soft tissue material and mitral valve material are described. In an embodiment, the network is composed of tyramine-substituted and cross-linked hyaluronan molecules, wherein cross-linking is achieved via peroxidase-mediated dityramine-linkages that can be performed in vivo. The dityramine bonds provide a stable, coherent hyaluronan-based hydrogel with desired physical properties.Type: GrantFiled: September 15, 2008Date of Patent: June 26, 2012Assignee: The Cleveland Clinic FoundationInventors: Anthony Calabro, Lee Akst, Daniel Alam, James Chan, Aniq B. Darr, Kiyotaka Fukamachi, Richard A. Gross, David Haynes, Keiji Kamohara, Daniel P. Knott, Hilel Lewis, Alex Melamud, Anthony Miniaci, Marshall Strome
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Patent number: 8021350Abstract: A dihydroxyphenyl cross-linked macromolecular network is provided that is useful in artificial tissue and tissue engineering applications, particularly to provide a synthetic macromolecular network for a wide variety of tissue types. In particular, artificial or synthetic cartilage, vocal cord material, vitreous material, soft tissue material and mitral valve material are described. In an embodiment, the network is composed of tyramine-substituted and cross-linked hyaluronan molecules, wherein cross-linking is achieved via peroxidase-mediated dityramine-linkages that can be performed in vivo. The dityramine bonds provide a stable, coherent hyaluronan-based hydrogel with desired physical properties.Type: GrantFiled: January 29, 2009Date of Patent: September 20, 2011Assignee: The Cleveland Clinic FoundationInventors: Anthony Calabro, Aniq B. Darr, Kiyotaka Fukamachi, Richard A. Gross, Keiji Kamohara, Michael K. Banbury
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Publication number: 20090142309Abstract: A dihydroxyphenyl cross-linked macromolecular network is provided that is useful in artificial tissue and tissue engineering applications, particularly to provide a synthetic macromolecular network for a wide variety of tissue types. In particular, artificial or synthetic cartilage, vocal cord material, vitreous material, soft tissue material and mitral valve material are described. In an embodiment, the network is composed of tyramine-substituted and cross-linked hyaluronan molecules, wherein cross-linking is achieved via peroxidase-mediated dityramine-linkages that can be performed in vivo. The dityramine bonds provide a stable, coherent hyaluronan-based hydrogel with desired physical properties.Type: ApplicationFiled: January 29, 2009Publication date: June 4, 2009Applicant: The Cleveland Clinic FoundationInventors: Anthony Calabro, Lee Akst, Daniel Alam, James Chan, Aniq B. Darr, Kiyotaka Fukamachi, Richard A. Gross, David Haynes, Keiji Kamohara, Daniel P. Knott, Hilel Lewis, Alex Melamud, Anthony Miniaci, Marshall Strome