Patents by Inventor Klaus Adrian

Klaus Adrian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Activated carbon for the removal of leachables and/or extractables
    Patent number: 10793592
    Abstract: The present invention relates to the purification of target molecules like recombinant and/or biotherapeutic proteins. Activated carbon can be used to remove leachables and/or extractables resulting from disposable equipment employed in the process.
    Type: Grant
    Filed: October 20, 2015
    Date of Patent: October 6, 2020
    Assignee: Merck Patent GmbH
    Inventors: Romas Skudas, Klaus Adrian, Bianca Edlemann, Sven Andrecht, Wilson Moya
  • Target molecule capture from crude solutions
    Patent number: 10617975
    Abstract: The present invention refers to a method for the separation of peptide aggregates and fragments from solutions containing target peptide.
    Type: Grant
    Filed: November 18, 2015
    Date of Patent: April 14, 2020
    Assignee: MERCK PATENT GMBH
    Inventors: Romas Skudas, Klaus Adrian, Bianca Edelmann, Matthias Joehnck
  • TARGET MOLECULE CAPTURE FROM CRUDE SOLUTIONS
    Publication number: 20170340989
    Abstract: The present invention refers to a method for the separation of peptide aggregates and fragments from solutions containing target peptide.
    Type: Application
    Filed: November 18, 2015
    Publication date: November 30, 2017
    Applicant: MERCK PATENT GMBH
    Inventors: Romas SKUDAS, Klaus ADRIAN, Bianca EDELMANN, Matthias JOEHNCK
  • ACTIVATED CARBON FOR THE REMOVAL OF LEACHABLES AND/OR EXTRACTABLES
    Publication number: 20170313741
    Abstract: The present invention relates to the purification of target molecules like recombinant and/or biotherapeutic proteins. Activated carbon can be used to remove leachables and/or extractables resulting from disposable equipment employed in the process.
    Type: Application
    Filed: October 20, 2015
    Publication date: November 2, 2017
    Applicant: Merck Patent GmbH
    Inventors: Romas SKUDAS, Klaus ADRIAN, Bianca EDLEMANN, Sven ANDRECHT, Wilson MOYA
  • Liquid oxidative desizing agent and process for oxidative desizing
    Patent number: 4478737
    Abstract: Oxidative desizing agent consisting substantially of from 5 to 20 weight % of sodium or ammonium persulfate or potassium, sodium, ammonium or calcium peroxodiphosphate, from 20 to 50 weight % of one or more surfactants selected from the group of C.sub.8 -C.sub.20 -sec.-alkanesulfonates, C.sub.4 -C.sub.12 -alkylphenol-oxethylates having 6 to 12 ethylene oxide moieties, or C.sub.10 -C.sub.18 -fatty alcohol-oxethylates having 3 to 8 ethylene oxide moieties, and water in the amount remaining to give 100%. The advantage of this desizing agent resides in the fact that a substantially smaller amount of persulfate is required than for desizing with persulfate alone. Moreover, this desizing agent is liquid and thus easy to be dosed.
    Type: Grant
    Filed: March 24, 1983
    Date of Patent: October 23, 1984
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Klaus Adrian, Gunter Rosch
  • Use of alkylpolyglycol-tert.-butyl ether as bleaching auxiliary and bleaching baths containing this agent
    Patent number: 4321052
    Abstract: A process for the bleaching of cellulose in an alkaline peroxide bleaching bath in the presence of a compound of the formula ##STR1## wherein R is C.sub.6 -C.sub.22 -alkyl, C.sub.6 -C.sub.22 -alkenyl or C.sub.6 -C.sub.22 -alkylaryl, n is a number of from 5 to 50, and X is ethylene or propylene; the ether chain (X-O).sub.n consisting entirely of ethoxy units or contains n/5 isopropoxy units at most.
    Type: Grant
    Filed: April 17, 1981
    Date of Patent: March 23, 1982
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Otto Smerz, Thomas Martini, Siegfried Billenstein, Klaus Adrian
  • Oxidative desizing agent and process for oxidative desizing
    Patent number: 4309298
    Abstract: Novel oxidative desizing agent consisting essentially of from 10 to 80, preferably 50 to 80% by weight of a surfactant and from 20 to 90, preferably 20 to 50% by weight of potassium persulfate. This desizing agent may optionally also contain from 5 to 25% by weight of a solubilizer with a simultaneous reduction of the surfactant and persulfate portions.
    Type: Grant
    Filed: March 28, 1980
    Date of Patent: January 5, 1982
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Klaus Adrian, Gunter Rosch