Patents by Inventor Klaus Bartel

Klaus Bartel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystalline potassium salt of lipoxin Aanalogs
    Patent number: 8049035
    Abstract: This invention is directed to the crystalline potassium salt of a lipoxin A4 analog of Formula (I): processes for preparing the crystalline potassium salts, methods for using them to treat disease-states characterized by inflammation, and pharmaceutical compositions comprising such crystalline potassium salts.
    Type: Grant
    Filed: February 7, 2011
    Date of Patent: November 1, 2011
    Assignee: Bayer Pharma AG
    Inventors: Tilo Haag, Danja Grossbach, Gabriele Winter, Michael Sander, Wolfgang Beckmann, Klaus Bartel, Christian Dinter
  • CRYSTALLINE POTASSIUM SALT OF LIPOXIN A4 ANALOGS
    Publication number: 20110124910
    Abstract: This invention is directed to the crystalline potassium salt of a lipoxin A4 analog of Formula (I): processes for preparing the crystalline potassium salts, methods for using them to treat disease-states characterized by inflammation, and pharmaceutical compositions comprising such crystalline potassium salts.
    Type: Application
    Filed: February 7, 2011
    Publication date: May 26, 2011
    Inventors: Tilo HAAG, Danja Grossbach, Gabriele Winter, Michael Sander, Wolfgang Beckmann, Klaus Bartel, Christian Dinter
  • Crystalline potassium salt of lipoxin A4 analogs
    Patent number: 7906678
    Abstract: This invention is directed to the crystalline potassium salt of a lipoxin A4 analog of Formula (I): processes for preparing the crystalline potassium salts, methods for using them to treat disease-states characterized by inflammation, and pharmaceutical compositions comprising such crystalline potassium salts.
    Type: Grant
    Filed: December 3, 2007
    Date of Patent: March 15, 2011
    Assignee: Bayer Schering Pharma Aktiengesellschaft
    Inventors: Tilo Haag, Danja Grossbach, Gabriele Winter, Michael Sander, Wolfgang Beckmann, Klaus Bartel, Christian Dinter
  • Crystalline acid of lipoxin A4 analogs and method of making
    Publication number: 20090036530
    Abstract: This invention is directed to a crystalline acid of a lipoxin A4 analog of Formula (II): wherein: R1 is —O—, —S(O)t— (where t is 0, 1 or 2), or a straight or branched alkylene chain; and R2 is aryl (optionally substituted by one or more substituents selected from alkyl, alkoxy, halo, haloalkyl and haloalkoxy) or aralkyl (optionally substituted by one or more substituents selected from f alkyl, alkoxy, halo, haloalkyl and haloalkoxy); and wherein the compound of Formula (II) is a single stereoisomer or any mixture of stereoisomers. This crystalline acid is useful in treating disease-states characterized by inflammation, such as inflammatory and autoimmune disorders or pulmonary or respiratory tract inflammations in humans. Methods of preparing the crystalline acid are also described.
    Type: Application
    Filed: June 30, 2008
    Publication date: February 5, 2009
    Applicant: Bayer Schering Pharma Aktiengesellschaft
    Inventors: Klaus Bartel, Danja Grossbach, William J. Guilford, Michael Sander, Gabriele Winter
  • Crystalline acid of lipoxin A4 analogs and method of making
    Publication number: 20080182901
    Abstract: This invention is directed to a crystalline acid of a lipoxin A4 analog of Formula (II): wherein: R1 is —O—, —S(O)t— (where t is 0, 1 or 2), or a straight or branched alkylene chain; and R2 is aryl (optionally substituted by one or more substituents selected from alkyl, alkoxy, halo, haloalkyl and haloalkoxy) or aralkyl (optionally substituted by one or more substituents selected from f alkyl, alkoxy, halo, haloalkyl and haloalkoxy); and wherein the compound of Formula (II) is a single stereoisomer or any mixture of stereoisomers. This crystalline acid is useful in treating disease-states characterized by inflammation, such as inflammatory and autoimmune disorders or pulmonary or respiratory tract inflammations in humans. Methods of preparing the crystalline acid are also described.
    Type: Application
    Filed: December 3, 2007
    Publication date: July 31, 2008
    Applicant: Bayer Schering Pharma Aktiengesellschaft
    Inventors: Klaus Bartel, Danja Grossbach, William J. Guilford, Michael Sander, Gabriele Winter
  • Crystalline potassium salt of lipoxin A4 analogs
    Publication number: 20080182897
    Abstract: This invention is directed to the crystalline potassium salt of a lipoxin A4 analog of Formula (I): processes for preparing the crystalline potassium salts, methods for using them to treat disease-states characterized by inflammation, and pharmaceutical compositions comprising such crystalline potassium salts.
    Type: Application
    Filed: December 3, 2007
    Publication date: July 31, 2008
    Applicant: Bayer Schering Pharma Aktiengesellschaft
    Inventors: Tilo Haag, Danja Grossbach, Gabriele Winter, Michael Sander, Wolfgang Beckmann, Klaus Bartel, Christian Dinter