Abstract: The present invention provides a drug delivery device (1) comprising: a drug reservoir (20) comprising a reservoir body (21) extending along a reference axis and an elastomeric stopper (30) arranged in the reservoir body (21), the elastomeric stopper (30) comprising a stopper body (31) extending between a front stopper end (32) and a rear stopper end (34) and having a plurality of axially spaced apart circumferential ribs (33) for sealing interaction with an interior wall (22) of the reservoir body (21), and a plunger rod structure (10) for displacing the elastomeric stopper (30) relative to the interior wall (22), the plunger rod structure (10) extending along the reference axis and comprising a distal end face (12, 14) adapted to interface with the rear stopper end (34).

Abstract: The present invention concerns an elastomeric stopper (18, 28, 38) for a drug reservoir, comprising: a stopper body (18.1, 28.1, 38.1) extending along a reference axis between a leading end surface (18.2, 28.2, 38.2) and a trailing end surface (18.3, 28.3, 38.3) and having a generally cylindrical sidewall with an outer body diameter, a circumferential convex rib (18.6, 28.6, 38.6) extending radially outwardly from the sidewall, a non-convex trim edge portion (18.7, 28.7, 38.7) at the trailing end surface (18.3, 28.3, 38.3), the non-convex trim edge portion (18.7, 28.7, 38.7) having an outer trim edge diameter which is greater than the outer body diameter and being axially spaced apart from the circumferential convex rib (18.6, 28.6, 38.6), providing an annular recess (18.9, 28.9, 38.9) therebetween. The elastomeric stopper (18, 28, 38) further comprises a channel structure (18.10, 28.10, 38.10) enabling fluid flow from the trailing end surface (18.3, 28.3, 38.3) to the annular recess (18.9, 28.9, 38.

Abstract: The present invention provides a drug delivery device (2, 3; 102) for sequential administration of substances, comprising a first variable volume reservoir (40a; 140a) holding a first substance and comprising a first outlet (41 a, 141 a) and a first displaceable wall (43a; 143a), a second variable volume reservoir (40b; 140b) holding a second substance and comprising a second outlet (41 b; 141 b) and a second displaceable wall (43b; 143b), a first wall actuation structure (65a, 70a, 75a, 77a; 177a) activatable to move the first displaceable wall (43a; 143a) and thereby expel a dose of the first substance through the first outlet (41 a; 141 a), a second wall actuation structure (65b, 70b, 75b, 77b; 177b) activatable to move the second displaceable wall (43b; 143b) and thereby expel a dose of the second substance through the second outlet (41 b; 141 b), and a drive structure (90; 190) for activating the first wall actuation structure (65a, 70a, 75a, 77a; 177a) and the second wall actuation structure (65b, 70b,

Abstract: The present invention provides a solution for zero-point adjustment of drug delivery devices, including twin chamber drug delivery devices with a single dose engine.

Abstract: The present invention provides a drug delivery device with a dose counting mechanism and an end-of-content identification.

Abstract: A method of manufacturing one of a range of autoinjectors having cartridges (600, 600?, 600?) with different preset fill volumes, the method comprising the steps of: a) providing a front body assembly (100b, 100c, 100c?, 100c?), b) providing a cartridge (600, 600?, 600?) of given fill volume, c) providing a rear body assembly (100a) comprising a spring-driven drive ram assembly (310, 320) configured to drive the piston of a held cartridge (600, 600?, 600?), d) providing a ram spacer member (400, 400?, 400?), the ram spacer member defining a spacing geometry of length dimension (X1?, X1?, X1??, XS?, XS?, XS??, XR?, XR?, XR??) selected according to the fill volume of the cartridge (600, 600?, 600?), and e) assembling a front body assembly (100b, 100c, 100c?, 100c?), the cartridge (600, 600?, 600?), the ram spacer member (400, 400?, 400?) and the rear body assembly (100a) so that the ram spacer member (400, 400?, 400?) is arranged axially between the drive ram assembly (310, 320) of the rear body assembly (100a)

Abstract: A needle unit (20) comprising: a needle hub (21) comprising a needle (23) and a needle shield (22), wherein the needle hub (21) and the needle shield (22) are arranged to form a needle unit (20) where the needle hub is arranged displaceably inside the needle shield such that the needle hub is displaceable along an axis which is parallel with the longitudinal axis of the needle (23) between a shielded position and an exposed position.

Abstract: The present invention provides a drug delivery device (2, 3; 102) for sequential administration of substances, comprising a first variable volume reservoir (40a; 140a) holding a first substance and comprising a first outlet (41 a, 141 a) and a first displaceable wall (43a; 143a), a second variable volume reservoir (40b; 140b) holding a second substance and comprising a second outlet (41 b; 141 b) and a second displaceable wall (43b; 143b), a first wall actuation structure (65a, 70a, 75a, 77a; 177a) activatable to move the first displaceable wall (43a; 143a) and thereby expel a dose of the first substance through the first outlet (41 a; 141 a), a second wall actuation structure (65b, 70b, 75b, 77b; 177b) activatable to move the second displaceable wall (43b; 143b) and thereby expel a dose of the second substance through the second outlet (41 b; 141 b), and a drive structure (90; 190) for activating the first wall actuation structure (65a, 70a, 75a, 77a; 177a) and the second wall actuation structure (65b, 70b,

Abstract: The present invention relates to a reservoir unit (40, 140, 240) for a drug delivery arrangement (1, 100, 200), the reservoir unit (40, 140, 240) comprising: a housing (41, 141, 241) adapted to accommodate a fluid substance and comprising a displaceable wall (43, 143, 243), a fluid transport member (50, 150, 250) comprising a fluid outlet (52, 152, 252), first fluid communication means (53, 153, 253) for providing fluid communication with an interior of another reservoir, and second fluid communication means (54, 154, 254) for providing fluid communication with an interior (44, 144, 244) of the housing (41, 141, 241), and coupling means (45, 145, 245) adapted for connection with mating coupling means associated with the other reservoir. The invention further relates to a drug delivery arrangement (1, 100, 200) employing the reservoir unit (40, 140, 240).

Abstract: A needle unit (20) comprising: a needle hub (21) comprising a needle (23) and a needle shield (22), wherein the needle hub (21) and the needle shield (22) are arranged to form a needle unit (20) where the needle hub is arranged displaceably inside the needle shield such that the needle hub is displaceable along an axis which is parallel with the longitudinal axis of the needle (23) between a shielded position and an exposed position.

Abstract: A method of manufacturing one of a range of autoinjectors having cartridges (600, 600?, 600?) with different preset fill volumes, the method comprising the steps of: a) providing a front body assembly (100b, 100c, 100c?, 100c?), b) providing a cartridge (600, 600?, 600?) of given fill volume, c) providing a rear body assembly (100a) comprising a spring-driven drive ram assembly (310, 320) configured to drive the piston of a held cartridge (600, 600?, 600?), d) providing a ram spacer member (400, 400?, 400?), the ram spacer member defining a spacing geometry of length dimension (X1?, X1?, X1??, XS?, XS?, XS??, XR?, XR?, XR??) selected according to the fill volume of the cartridge (600, 600?, 600?), and e) assembling a front body assembly (100b, 100c, 100c?, 100c?), the cartridge (600, 600?, 600?), the ram spacer member (400, 400?, 400?) and the rear body assembly (100a) so that the ram spacer member (400, 400?, 400?) is arranged axially between the drive ram assembly (310, 320) of the rear body assembly (100a)

Abstract: The present invention relates to a medical device (1, 100) comprising a first container (10, 110) holding a first medium and defining a general axis, a second container (20, 120) holding a second medium, and fluid connection means (50, 150) for establishing fluid connection between the first container (10, 110) and the second container (20, 120), the fluid connection means (50, 150) being arranged at least partially between the first container (10, 110) and the second container (20, 120). The device further comprises a cover receiving portion (42, 42) and a cover (4, 104) removably mounted thereon to shield at least an operable portion of the first container (10, 110).

Abstract: The present invention relates to a medical device comprising a base member (2), a container (20) comprising a container interior (28) adapted to accommodate a substance, and a container closure (23) for fluidly sealing the container interior, and fluid connection means (50) for establishing fluid connection to the container interior. A cover (4) removably mountable on a cover receiving portion (36) is operatively coupled with the fluid connection means (50) to cause a relative motion between the fluid connection means (50) and the container closure (23) in response to a relative motion between the cover (4) and the base member (2).

Abstract: The present invention relates to a medical device (1, 100) comprising a first container (10, 110) holding a first medium and defining a general axis, a second container (20, 120) holding a second medium, and fluid connection means (50, 150) for establishing fluid connection between the first container (10, 110) and the second container (20, 120), the fluid connection means (50, 150) being arranged at least partially between the first container (10, 110) and the second container (20, 120). The device further comprises a cover receiving portion (42, 42) and a cover (4, 104) removably mounted thereon to shield at least an operable portion of the first container (10, 110).

Abstract: The present invention relates to a reservoir unit (40, 140, 240) for a drug delivery arrangement (1, 100, 200), the reservoir unit (40, 140, 240) comprising: a housing (41, 141, 241) adapted to accommodate a fluid substance and comprising a displaceable wall (43, 143, 243), a fluid transport member (50, 150, 250) comprising a fluid outlet (52, 152, 252), first fluid communication means (53, 153, 253) for providing fluid communication with an interior of another reservoir, and second fluid communication means (54, 154, 254) for providing fluid communication with an interior (44, 144, 244) of the housing (41, 141, 241), and coupling means (45, 145, 245) adapted for connection with mating coupling means associated with the other reservoir. The invention further relates to a drug delivery arrangement (1, 100, 200) employing the reservoir unit (40, 140, 240).

Abstract: A device (1) for mixing substances to obtain an injectable medical product, the device (1) comprising a cartridge (50), a front piston (5), a front chamber (17) containing a liquid or a powder, a rear piston (6), a rear chamber (18) containing a liquid, a piston rod (7), and a bypass channel (19). The piston rod (7) is adapted to advance the rear piston (6) to collapse the rear chamber (18), whereby the liquid in the rear chamber (18) is forced to move to the front chamber (17) via the bypass channel (19). The piston rod (7) has a projection (10) which is adapted to mate with a recess (12) in the front piston (5) to provide an interlocking between the two components.