Patents by Inventor Klaus Buchner

Klaus Buchner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Clock Monitoring for Sequential Logic Circuits
    Publication number: 20160094212
    Abstract: A monitor circuit for monitoring a clock signal is described. In accordance with one example of the disclosure, the monitor circuit includes a pulse generator and a comparator circuit. The pulse generator is configured to generate a sequence of pulses synchronous to the clock signal, wherein each pulse has an edge with a monotonously rising or falling signal level. The comparator circuit receives the sequence of pulses and is configured to detect, for each clock cycle of the clock signal, whether or not the signal level of the sequence of pulses is outside a desired range at a specific time instant within the clock cycle of the clock signal.
    Type: Application
    Filed: September 26, 2014
    Publication date: March 31, 2016
    Inventors: Klemens Kordik, Bernhard Gstoettenbauer, Klaus Buchner, Thomas Sailer
  • SDF-1 Binding Nucleic Acids
    Publication number: 20150232853
    Abstract: The present invention is related to an L nucleic acid that binds to an SDF-1.
    Type: Application
    Filed: May 6, 2015
    Publication date: August 20, 2015
    Inventors: Werner Purschke, Florian Jarosch, Dirk Eulberg, Sven Klussmann, Klaus Buchner, Christian Maasch, Nicole Dinse
  • Glucagon Binding Nucleic Acids
    Publication number: 20150232852
    Abstract: The present invention is related to a nucleic acid molecule capable of binding to a target molecule, wherein the nucleic acid molecule has a binding affinity to the target molecule, wherein the binding affinity of the nucleic acid molecule to the target molecule is increased or the same compared to the binding affinity of a reference nucleic acid molecule to the target molecule, wherein a) the nucleic acid molecule comprises a sequence of nucleotides and the reference nucleic acid molecule comprises a sequence of nucleotides, or b) the nucleic acid molecule comprises a sequence of nucleotides and at least one modification group and the reference nucleic acid molecule comprises a sequence of nucleotides and the at least one modification group, wherein the sequence of nucleotides of the nucleic acid molecule and the sequence of nucleotides of the reference nucleic acid molecule are at least partially identical with respect to the nucleobase moiety of the nucleotides but differ with respect to the sugar moie
    Type: Application
    Filed: October 22, 2012
    Publication date: August 20, 2015
    Inventors: Werner Purschke, Simone Sell, Axel Vater, Klaus Buchner, Christian Maasch, Sven Klussmann
  • Use of spiegelmers
    Patent number: 9074214
    Abstract: The present invention relates to the use of a L-nucleic acid as intracellularly active agent.
    Type: Grant
    Filed: July 30, 2013
    Date of Patent: July 7, 2015
    Assignee: NOXXON Pharma AG
    Inventors: Axel Vater, Christian Maasch, Sven Klussmann, Werner Purschke, Dirk Eulberg, Florian Jarosch, Klaus Buchner
  • MCP-1 Binding Nucleic Acids and Use Thereof
    Publication number: 20150141496
    Abstract: The present invention is related to a nucleic acid molecule capable of binding to MCP-I, whereby the nucleic acid molecule is for use as a medicament for the treatment and/or prevention of a chronic disease or chronic disorder, preferably selected from the group consisting of chronic respiratory disease, chronic kidney disease and systemic lupus erythematosus.
    Type: Application
    Filed: May 15, 2014
    Publication date: May 21, 2015
    Applicant: NOXXON PHARMA AG
    Inventors: Werner Purschke, Florian Jarosch, Dirk Eulberg, Sven Klussmann, Klaus Buchner, Christian Maasch
  • SDF-1 binding nucleic acids
    Patent number: 9035038
    Abstract: The present invention is related to an L nucleic acid that binds to an SDF-1.
    Type: Grant
    Filed: October 13, 2012
    Date of Patent: May 19, 2015
    Assignee: NOXXON Pharma AG
    Inventors: Werner Purschke, Florian Jarosch, Dirk Eulberg, Sven Klussmann, Klaus Buchner, Christian Maasch, Nicole Dinse
  • SDF-1 Binding Nucleic Acids and the Use Thereof
    Publication number: 20140370034
    Abstract: The present invention is related to a nucleic acid molecule binding to SDF-1, whereby the nucleic acid molecule influences migration of cells.
    Type: Application
    Filed: July 6, 2014
    Publication date: December 18, 2014
    Inventors: Werner Purschke, Florian Jarosch, Dirk Eulberg, Sven Klussmann, Klaus Buchner, Christian Maasch, Nicole Dinse
  • New C5a Binding Nucleic Acids
    Publication number: 20140364487
    Abstract: The present invention is related to a nucleic acid molecule capable of binding to human C5a, wherein the nucleic acid molecule comprises a central stretch of nucleotides, wherein the central stretch of nucleotides comprises a nucleotide sequence of 5? AUGn1GGUGKUn2n3RGGGHUGUKGGGn4Gn5CGACGCA 3? [SEQ ID NO: 61], wherein n1 is U or dU, n2 is G or dG, n3 is A or dA, n4 is U or dU, n5 is U or dU and G, A, U, C, H, K, and R are ribonucleotides, and dU, dG and dA are 2?-deoxyribonucleotides.
    Type: Application
    Filed: January 10, 2013
    Publication date: December 11, 2014
    Inventors: Kai Hohlig, Axel Vater, Klaus Buchner, Christian Maasch, Sven Klussmann
  • Interface circuit and method for enabling an output driver of the interface circuit
    Patent number: 8908748
    Abstract: An interface circuit includes an interface terminal, a voltage detection device, an output driver and an enable logic. The interface terminal is configured to connect to an interface line. The voltage detection device is configured to detect a voltage present at the interface terminal. The output driver is configured to apply an output signal to the interface terminal. The enable logic is configured to generate an enable signal for the output driver based on an evaluation signal output by the voltage detection device, wherein the enable signal affects an enabling of the output driver if the evaluation signal shows that the voltage present at the interface terminal meets a given condition.
    Type: Grant
    Filed: October 15, 2012
    Date of Patent: December 9, 2014
    Inventors: Klaus Buchner, Klemens Kordik, Christian Unhold
  • Lipid binding nucleic acids
    Patent number: 8871920
    Abstract: The present invention is related to a nucleic acid molecule capable of binding to a lipid.
    Type: Grant
    Filed: April 21, 2011
    Date of Patent: October 28, 2014
    Assignee: NOXXON Pharma AG
    Inventors: Werner Purschke, Sven Klussmann, Klaus Buchner, Frank Schwobel, Kai Hoehlig
  • Hepcidin binding nucleic acids
    Patent number: 8841431
    Abstract: The present invention is related to a nucleic acid capable of binding to hepcidin.
    Type: Grant
    Filed: April 30, 2010
    Date of Patent: September 23, 2014
    Assignee: NOXXON Pharma AG
    Inventors: Simone Sell, Frank Morich, Christian Maasch, Sven Klussmann, Nicole Dinse, Klaus Buchner, Frank Schwobel
  • SDF-1 binding nucleic acids and the use thereof
    Patent number: 8772257
    Abstract: The present invention is related to a nucleic acid molecule binding to SDF-1, whereby the nucleic acid molecule influences migration of cells.
    Type: Grant
    Filed: August 6, 2008
    Date of Patent: July 8, 2014
    Assignee: NOXXON Pharma AG
    Inventors: Werner Purschke, Florian Jarosch, Dirk Eulberg, Sven Klussmann, Klaus Buchner, Christian Maasch, Nicole Dinse
  • MCP-1 binding nucleic acids
    Patent number: 8691784
    Abstract: The present invention is related to a nucleic acid, preferably binding to MCP-1, selected from the group consisting of Type 1A nucleic acids, type 1B nucleic acids, Type 2 nucleic acids, Type 3 nucleic acids, Type 4 nucleic acids and nucleic acids comprising SEQ ID NOs:87-115.
    Type: Grant
    Filed: June 4, 2012
    Date of Patent: April 8, 2014
    Assignee: NOXXON Pharma AG
    Inventors: Werner Purschke, Florian Jarosch, Dirk Eulberg, Sven Klussmann, Klaus Buchner, Christian Maasch
  • Novel Use of Spiegelmers
    Publication number: 20130337049
    Abstract: The present invention relates to the use of a L-nucleic acid as intracellularly active agent.
    Type: Application
    Filed: July 30, 2013
    Publication date: December 19, 2013
    Applicant: NOXXON Pharma AG
    Inventors: Axel Vater, Christian Maasch, Sven Klussmann, Werner Purschke, Dirk Eulberg, Florian Jarosch, Klaus Buchner
  • SDF-1 Binding Nucleic Acids and the use Thereof in Cancer Treatment
    Publication number: 20130310442
    Abstract: The present invention is related to a nucleic acid molecule capable of binding to SDF-1, preferably capable of inhibiting SDF-1, whereby the nucleic acid molecule is for use in a method for the treatment and/or prevention of a disease or disorder, for use in a method for the treatment of a subject suffering from a disease or disorder or being at risk of developing a disease or disorder as an adjunct therapy, or for use as a medicament for the treatment and/or prevention of a disease or disorder, whereby the disease or disorder is cancer.
    Type: Application
    Filed: September 9, 2011
    Publication date: November 21, 2013
    Applicant: NOXXON PHARMA AG
    Inventors: Werner Purschke, Florian Jarosch, Dirk Eulberg, Sven Klussmann, Klaus Buchner, Christian Maasch, Nicole Dinse, Dirk Zboralski
  • C5a binding nucleic acids
    Patent number: 8507456
    Abstract: The present invention is related to a nucleic acid, preferably binding to C5a, selected from the group comprising type A nucleic acids, type B nucleic acids, type C nucleic acids, type D nucleic acids and nucleic acids having a nucleic acid sequence according to any of SEQ.ID.No. 73 to 79.
    Type: Grant
    Filed: September 24, 2008
    Date of Patent: August 13, 2013
    Assignee: NOXXON Pharma AG
    Inventors: Werner Purschke, Florian Jarosch, Dirk Eulberg, Sven Klussmann, Klaus Buchner, Christian Maasch
  • Use of spiegelmers to inhibit an intracellular target molecule
    Patent number: 8497250
    Abstract: The present invention relates to the use of a L-nucleic acid as intracellularly active agent.
    Type: Grant
    Filed: May 4, 2006
    Date of Patent: July 30, 2013
    Assignee: NOXXON Pharma AG
    Inventors: Axel Vater, Christian Maasch, Sven Klussmann, Werner Purschke, Dirk Eulberg, Florian Jarosch, Klaus Buchner
  • Lipid Binding Nucleic Acids
    Publication number: 20130165501
    Abstract: The present invention is related to a nucleic acid molecule capable of binding to a lipid.
    Type: Application
    Filed: April 21, 2011
    Publication date: June 27, 2013
    Applicant: NOXXON PHARMA AG
    Inventors: Werner Purschke, Sven Klussmann, Klaus Buchner, Frank Schwoebel, Kai Hoehlig
  • MCP-1 binding nucleic acids
    Publication number: 20130035376
    Abstract: The present invention is related to a nucleic acid, preferably binding to MCP-1, selected from the group consisting of Type 1A nucleic acids, type 1B nucleic acids, Type 2 nucleic acids, Type 3 nucleic acids, Type 4 nucleic acids and nucleic acids comprising SEQ ID NOs:87-115
    Type: Application
    Filed: June 4, 2012
    Publication date: February 7, 2013
    Applicant: NOXXON PHARMA AG
    Inventors: Werner Purschke, Florian Jarosch, Dirk Eulberg, Sven Klussmann, Klaus Buchner, Christian Maasch
  • MCP-1 binding nucleic acids and use thereof
    Patent number: 8367629
    Abstract: The present invention is related to a nucleic acid molecule capable of binding to MCP-1, whereby the nucleic acid molecule is for use as a medicament for the treatment and/or prevention of a chronic disease or chronic disorder, preferably selected from the group consisting of chronic respiratory disease, chronic kidney disease and systemic lupus erythematosus.
    Type: Grant
    Filed: November 29, 2008
    Date of Patent: February 5, 2013
    Assignee: NOXXON Pharma AG
    Inventors: Werner Purschke, Florian Jarosch, Dirk Eulberg, Sven Klussmann, Klaus Buchner, Christian Maasch