Patents by Inventor Klaus Dress

Klaus Dress has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 4-METHYLPYRIDOPYRIMIDINONE COMPOUNDS
    Publication number: 20080090801
    Abstract: The present invention is directed to novel 4-methylpyridopyrimidinone compounds of Formula (I), and to salts thereof, their synthesis, and their use as inhibitors of phosphoinositide 3-kinase alpha (PI3-K?).
    Type: Application
    Filed: September 13, 2007
    Publication date: April 17, 2008
    Inventors: Hengmiao Cheng, Dilip Bhumralkar, Klaus Dress, Jacqui Hoffman, Mary Johnson, Robert Kania, Phuong Le, Mitchell Nambu, Mason Pairish, Michael Plewe, Khanh Tran
  • Inhibitors of the Hiv Integrase Enzyme
    Publication number: 20070232644
    Abstract: The present invention relates to compounds of formula (I), or a pharmaceutically acceptable salt or solvate thereof, pharmaceutical compositions comprising compounds of formula (I), and their methods of use in treating HIV-infected mammals.
    Type: Application
    Filed: August 26, 2005
    Publication date: October 4, 2007
    Inventors: Klaus Dress, Jon Kuehler, Michael Plewe, Anle Yang, Junhu Zhang
  • INHIBITORS OF THE HIV INTEGRASE ENZYME
    Publication number: 20070099915
    Abstract: The present invention is directed to compounds of formula (I), and pharmaceutically acceptable salts and solvates thereof, their synthesis, and their use as modulators or inhibitors of the human immunodeficiency virus (“HIV”) integrase enzyme.
    Type: Application
    Filed: October 6, 2006
    Publication date: May 3, 2007
    Inventors: Klaus Dress, Ted Johnson, Michael Plewe, Steven Tanis, Huichun Zhu
  • Novel compounds of amino sulfonyl derivatives
    Publication number: 20070027118
    Abstract: The present invention relates to compounds with formula (I) or a pharmaceutically acceptable salt thereof: wherein; T is a (4 to 10)-membered heterocyclyl and wherein R1, R2 and R3 are as defined in the specification. The invention also relates to pharmaceutical compositions comprising the compounds of formula (I) and methods of treating a condition that is mediated by the modulation of the 11-?-hsd-1 enzyme.
    Type: Application
    Filed: April 6, 2006
    Publication date: February 1, 2007
    Inventors: Hengmiao Cheng, Stephan Cripps, Klaus Dress, Buwen Huang, Sajiv Nair, Yong Wang
  • Inhibitors of the HIV integrase enzyme
    Publication number: 20050277661
    Abstract: The present invention is directed to compounds of formula (i), and pharmaceutically acceptable salts and solvates thereof, their synthesis, and their use as modulators or inhibitors of the human immunodeficiency virus (“HIV”) integrase enzyme.
    Type: Application
    Filed: April 25, 2005
    Publication date: December 15, 2005
    Inventors: Klaus Dress, Qiyue Hu, Ted Johnson, Michael Plewe, Steven Tanis, Huichun Zhu, Junhu Zhang
  • Inhibitors of the HIV integrase enzyme
    Publication number: 20050277662
    Abstract: The present invention is directed to compounds of formula (I), and pharmaceutically acceptable salts and solvates thereof, their synthesis, and their use as modulators or inhibitors of the human immunodeficiency virus (“HIV”) integrase enzyme.
    Type: Application
    Filed: April 25, 2005
    Publication date: December 15, 2005
    Inventors: Klaus Dress, Qiyue Hu, Ted Johnson, Michael Plewe, Steven Tanis, Hai Wang, Anle Yang, Chunfeng Yin, Junhu Zhang
  • Novel compounds of proline and morpholine derivatives
    Publication number: 20050261290
    Abstract: The present invention relates to compounds with the formulas (I), (II), and (III), or a pharmaceutically acceptable salt thereof: wherein T is a (4 to 10)-membered heterocyclyl selected from the group consisting of and wherein R1, R2 and R3 are as defined in the specification. The invention also relates to pharmaceutical compositions comprising the compounds of formulas (I), (II), and (III) and methods of treating a condition that is mediated by the modulation of the 11-?-hsd-1 enzyme, the method comprising administering to a mammal an effective amount of a compound of formulas (I), (II), and (III).
    Type: Application
    Filed: May 4, 2005
    Publication date: November 24, 2005
    Inventors: Hengmiao Cheng, Stephan Cripps, Klaus Dress, Jacqui Hoffman, Buwen Huang, Stanley Kupchinsky, Phuong Le, Sajiv Nair, Timothy Parrott, Christopher Smith, Yong Wang, Yi Yang
  • HIV protease inhibitors, compositions containing the same, their pharmaceutical uses and materials for their synthesis
    Publication number: 20050124683
    Abstract: The present invention relates to a series of chemical compounds useful as Human Immunodeficiency Virus (HIV) protease inhibitors and to the use of such compounds as antiviral agents.
    Type: Application
    Filed: September 16, 2004
    Publication date: June 9, 2005
    Inventors: Larry Alegria, Stacie Canan-Koch, Klaus Dress, Buwen Huang, Robert Kumpf, Kathleen Lewis, Jean Matthews, Sylvie Sakata, Scott Virgil