Patents by Inventor Klaus Ehrlich

Klaus Ehrlich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Coniosulfides and their derivatives, processes for preparing them, and their use as pharmaceuticals
    Publication number: 20050209308
    Abstract: Coniosulfides and their derivatives, processes for preparing them, and their use as pharmaceuticals. The present invention relates to the use of a compound of the formula (VI) for producing a pharmaceutical for the treatment and prophylaxis of degenerative neuropathics or of Alzheimer's disease.
    Type: Application
    Filed: May 18, 2005
    Publication date: September 22, 2005
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Laszlo Vertesy, Klaus Ehrlich, Marian Segeth, Luigi Toti
  • Coniosulfides and their derivatives, processes for preparing them, and their use as pharmaceuticals
    Patent number: 6927236
    Abstract: The present invention relates to compounds of the formula which are formed during fermentation by the microorganism Coniochaeta ellipsoidea Udagawa, DSM 13856, or by one of its mutations and/or variants, and chemically derivatized if appropriate. The invention furthermore relates to a process for preparing compounds of the formula (I), and to their use as pharmaceuticals. In addition, the invention relates to the use of a compound of the formula (VI) for producing a pharmaceutical for the treatment and prophylaxis of degenerative neuropathics or of Alzheimer's disease.
    Type: Grant
    Filed: September 19, 2002
    Date of Patent: August 9, 2005
    Assignee: Aventis Pharma Deutschland GmbH.
    Inventors: Laszlo Vertesy, Klaus Ehrlich, Michael Kurz, Marian Paul Segeth, Luigi Toti
  • Cyclipostins, process for their preparation and use thereof
    Patent number: 6756402
    Abstract: The invention relates to compounds of formula I in which R1, R2, E, X1, X2, and X3 have the meaning as described in the specification and claims, obtained by culturing Streptomyces species HAG 004107 (DSM 13381), and their physiologically tolerable salts and chemical equivalents. The invention furthermore relates to a process for the preparation of the cyclipostins, the microorganism HAG 004107 (DSM 13381), the use of the cyclipostins and their physiologically tolerable salts and chemical equivalents as pharmaceuticals, in particular as inhibitors of lipases, and pharmaceutical preparations which contain cyclipostin or a physiologically tolerable salt or equivalent thereof.
    Type: Grant
    Filed: June 22, 2001
    Date of Patent: June 29, 2004
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Laszlo Vertesy, Klaus Ehrlich, Michael Kurz, Joachim Wink
  • Coniosulfides and their derivatives, processes for preparing them, and their use as pharmaceuticals
    Publication number: 20030158117
    Abstract: The present invention relates to compounds of the formula 1
    Type: Application
    Filed: September 19, 2002
    Publication date: August 21, 2003
    Inventors: Laszlo Vertesy, Klaus Ehrlich, Michael Kurz, Marian Paul Segeth, Luigi Toti
  • Pluraflavins and derivatives thereof, process for their preparation and use thereof
    Patent number: 6500936
    Abstract: The invention relates to a compound of formula (I) wherein R1 is a sugar; R2 is —CH2—O—(R7)m, R7 representing a sugar, or is —COOH; R3 is an epoxide-comprising group, or is C1-C6-alkyl or C2-C6-alkenyl, unsubstituted or substituted by at least one OH; R5 is H, C1-C6-alkyl, C2-C6-alkenyl or C2-C6-alkynyl; R4R6, R8 and R10 independently of one another are H; C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, —X2H, or —X2R12, or R4 and R6 together and/or R8 and R10 together are =X2; X2 is O, NH, N—C1-C6-alkyl, N—C2-C6-alkenyl, N-C2-C6-alkynyl or S; R12 is C1-C6-alkyl, C2-C6—alkenyl, C2-C6-alkynyl, aryl or acyl; and m and n are 1 or 2; in any of its stereochemical forms and mixtures of these forms in any ratio, and a physiologically acceptable salt or derivative thereof. The compounds are obtainable from a culture of the microorganism Actinomycetales species HAG 003959, DSM 12931, by fermentation.
    Type: Grant
    Filed: February 16, 2001
    Date of Patent: December 31, 2002
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Laszlo Vertesy, Klaus Ehrlich, Martin Knauf, Joachim Wink, Francis P. Barbone, Elaine A. Powers, Elizabeth A. Cashman
  • Cyclipostins, process for their preparation and use thereof
    Publication number: 20020058645
    Abstract: The invention relates to compounds of formula I 1
    Type: Application
    Filed: June 22, 2001
    Publication date: May 16, 2002
    Inventors: Laszlo Vertesy, Klaus Ehrlich, Michael Kurz, Joachim Wink
  • Pluraflavins and derivatives thereof, process for their preparation and use thereof
    Publication number: 20020028921
    Abstract: The invention relates to a compound of formula (l) 1
    Type: Application
    Filed: February 16, 2001
    Publication date: March 7, 2002
    Inventors: Laszlo Vertesy, Klaus Ehrlich, Martin Knauf, Joachim Wink, Francis P. Barbone, Elaine A. Powers, Elizabeth A. Cashman