Patents by Inventor Klaus Gellner

Klaus Gellner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Identification of a new member of the cytochrome P450 3A (CYP3A) gene family: CYP3AX
    Patent number: 6645745
    Abstract: The present invention relates to polynucleotides encoding the CYP3AX protein and variants thereof. Further, the present invention also provides vectors comprising said polynucleotides, in particular vectors, wherein polynucleotides of the present invention are operatively linked to regulatory elements allowing expression in prokaryotic and/or eukaryotic host cells. In addition, the present invention relates to proteins encoded by said polynucleotides and antibodies specifically recognizing such proteins. The present invention also concerns transgenic non-human animals comprising the above-described polynucleotide or vectors. Moreover, the present invention relates to methods for identifying and obtaining drug candidates and inhibitors for therapy of disorders related to the malfunction of the CYP3AX genes as well as to methods of diagnosing the status of such disorders. The present invention also relates to methods for the identification of molecular variants of the CYP3AX polynucleotide or protein.
    Type: Grant
    Filed: May 30, 2000
    Date of Patent: November 11, 2003
    Assignee: Epidauros Biotechnologie AG
    Inventors: Leszek Wojnowski, Klaus Gellner, Regina Eiselt
  • Identification of a new member of the cytochrome P450 3A (CYP3A): gene family: CYP3AX
    Publication number: 20020160479
    Abstract: The present invention relates to polynucleotides encoding the CYP3AX protein and variants thereof. Further, the present invention also provides vectors comprising said polynucleotides, in particular vectors, wherein polynucleotides of the present invention are operatively linked to regulatory elements allowing expression in prokaryotic and/or eukaryotic host cells. In addition, the present invention relates to proteins encoded by said polynucleotides and antibodies specifically recognizing such proteins. The present invention also concerns transgenic non-human animals comprising the above-described polynucleotide or vectors. Moreover, the present invention relates to methods for identifying and obtaining drug candidates and inhibitors for therapy of disorders related to the malfunction of the CYP3AX genes as well as to methods of diagnosing the status of such disorders. The present invention also relates to methods for the identification of molecular variants of the CYP3AX polynucleotide or protein.
    Type: Application
    Filed: November 9, 2001
    Publication date: October 31, 2002
    Applicant: Epidauros Biotechnologie AG
    Inventors: Leszek Wojnowski, Klaus Gellner, Regina Eiselt