Patents by Inventor Klaus Gottlieb

Klaus Gottlieb has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200108130
    Abstract: The present invention provides, in part, formulations comprising a beta-lactamase. Particularly, modified-release powder formulations comprising a beta-lactamase are provided which release a substantial amount of the beta-lactamase in the intestines. Therapeutic uses of the beta-lactamase formulations are also provided.
    Type: Application
    Filed: March 20, 2018
    Publication date: April 9, 2020
    Inventors: Andrew BRISTOL, Klaus GOTTLIEB, J. Blair WEST
  • Publication number: 20190277833
    Abstract: The present invention relates, in part, to treatment of various diseases and disorders such as GI disorders through modulation of F420-dependent enzymes including specific enzymes involved in methanogenesis.
    Type: Application
    Filed: May 12, 2017
    Publication date: September 12, 2019
    Inventors: Klaus GOTTLIEB, Michael KALEKO, Vincent J. WACHER, Steven M. MUSKAL
  • Patent number: 6313334
    Abstract: Ferrocene dicarboxylic acid diesters have the general formula (I), in which X stands for an oligoethylene glycol radical with 2 to 20 ethoxyl units and/or an &agr;,&ohgr;-alkyldiol radical with 2 to 18 C atoms. Also disclosed are processes for preparing the same, their use, solid composite propellants containing the disclosed ferrocene dicarboxylic acid diesters and processes for preparing the same.
    Type: Grant
    Filed: June 7, 2000
    Date of Patent: November 6, 2001
    Assignees: Dynamit Nobel GmbH Explosivstoff - und Systemtechnik, Chemische Betriebe Pluto GmbH
    Inventors: Hans-Peter Hebekeuser, Hans-Peter MacKowiak, Klaus Gottlieb, Hubert Jungbluth, Horst Neitsch
  • Patent number: 5780688
    Abstract: The invention concerns a supported catalyst in the form of packing and constructed on an open-pore support material on whose external and internal surfaces a macro-porous ion exchange resin is mechanically and/or chemically affixed.
    Type: Grant
    Filed: April 5, 1996
    Date of Patent: July 14, 1998
    Assignee: Veba Oel AG
    Inventors: Ulrich Hoffmann, Ulrich Kunz, Hartmut Bruderreck, Klaus Gottlieb, Kuno Schadlich, Stefan Becker
  • Patent number: 5717122
    Abstract: Ferrocene compounds are produced from related intermediates, wherein the ferrocene compounds are represented by the general formula (I): ##STR1## wherein Z is one of the groups --CH.sub.2 --Y, --CO--(CH.sub.2).sub.n --CO--X or --CO--X, in which n is 1 to 6; X is an (oligo-)alkylene glycol residue with 1 to 10 alkoxy units or an alkanediol residue with 2 to 18 carbon atoms, and Y is X or OH, andR is an alkyl group with 2 to 18 carbon atoms, an aralkyl group with 7 to 20 carbon atoms, or H, when Y.noteq.OH.The related intermediates differ from the ferrocene compound in that Z is replaced by Z' which is --COOH or --CO--(CH.sub.2).sub.n --COOH. The ferrocene compounds of formula (I) are especially suitable as combustion moderators for solid fuels.
    Type: Grant
    Filed: May 6, 1996
    Date of Patent: February 10, 1998
    Assignee: Chemische Betriebe Pluto GmbH
    Inventors: Klaus Gottlieb, Hubert Jungbluth, Horst Neitsch
  • Patent number: 5244929
    Abstract: Molded bodies in the form of packing bodies comprising a macroporous strongly acid or basic ion exchange resin having a voids fraction of 5-95 vol % of the macro shape without pores, a BET surface area of 0.1-1,000 sq m/g, and an ion exchange capacity of 0.05-10 meq/g.
    Type: Grant
    Filed: May 11, 1992
    Date of Patent: September 14, 1993
    Assignee: Veba Oel Aktiengesellschaft
    Inventors: Klaus Gottlieb, Wilfried Graf, Kuno Schadlich, Ulrich Hoffmann, Alwin Rehfinger, Jorg Flato
  • Patent number: 5053580
    Abstract: Metal oxide powders comprised of Cr(III) oxide, Ti(IV) oxide, V(V) oxide, or mixtures of these, or metal mixed oxides comprised of Cr(III) oxide and Ti(IV) oxide and V(V) oxide, or their mixtures. They have BET surfaces of 5-50m.sup.2 /g and mean particle diameters of 25-350 nm and are useful to increase conversion and selectivity in the manufacture of mono-olefins by catalytic dehydrogenation of saturated hydrocarbons. The metal oxide powders are produced from mixtures of the vaporized metal compounds chromyl chloride, titanium tetrachloride, and vanadyl chloride, in the presence of certain gases by laser pyrolysis.
    Type: Grant
    Filed: May 7, 1990
    Date of Patent: October 1, 1991
    Assignee: Veba Oel Aktiengesellschaft
    Inventors: Bernhard Schramm, Jurgen Kern, Harald Schwahn, August-Wilhelm Preuss, Klaus Gottlieb, Hartmut Bruderreck
  • Patent number: 5013706
    Abstract: Metal oxide powders comprised of Cr(III) oxide, Ti(IV) oxide, V(V) oxide, or mixtures of these, or metal mixed oxides comprised of Cr(III) oxide and Ti(IV) oxide and V(V) oxide, or their mixtures. They have BET surfaces of 5-50 m.sup.2 /g and mean particle diameters of 25-350 nm and are useful to increase conversion and selectivity in the manufacture of mono-olefins by catalytic dehydrogenation of saturated hydrocarbons. The metal oxide powders are produced from mixtures of the vaporized metal compounds chromyl chloride, titanium tetrachloride, and vanadyl chloride, in the presence of certain gases by laser pyrolysis.
    Type: Grant
    Filed: June 6, 1989
    Date of Patent: May 7, 1991
    Assignee: Veba Oel Aktiengesellschaft
    Inventors: Bernhard Schramm, Jurgen Kern, Harald Schwahn, August-Wilhelm Preuss, Klaus Gottlieb, Hartmut Bruderreck
  • Patent number: 4704497
    Abstract: A process for dehydrogenating saturated or unsaturated hydrocarbons wherein the flow direction of the oxygen-containing gas, employed for removing coke deposits on the catalyst surface, is opposite to that for the hydrocarbon feed undergoing dehydrogenation.
    Type: Grant
    Filed: July 14, 1986
    Date of Patent: November 3, 1987
    Assignee: Veba Oel AG
    Inventors: Klaus Gottlieb, Wilfried Graf, Heinz-Kuno Schadlich
  • Patent number: 4664904
    Abstract: Atomic hydrogen for chemical reaction is produced in relatively high concentrations by the combustion of molecular hydrogen with a substoichiometric quantity of oxygen. The chemical reactant is supplied at the point of the development of the atomic hydrogen. Combustion is effected at pressures between 10 mbar and 1.5 bar, with a mole ratio of molecular hydrogen to molecular oxygen of 2.3 to 5.0.
    Type: Grant
    Filed: September 25, 1985
    Date of Patent: May 12, 1987
    Assignee: Veba Oel Ag
    Inventors: Jurgen Wolfrum, Jurgen Warnatz, Hartmut Bruderreck, Klaus Gottlieb, August-Wilhelm Preuss
  • Patent number: 4468233
    Abstract: A motor fuel comprising 35-98% hydrocarbon-containing base and 2-65% by volume of an additive which comprises a mixture containing(a) 5-35% by volume of methyl tert-butyl ether;(b) 5-40% by volume of isopropyl tert-butyl ether; and(c) 5-40% by volume of sec-butyl tert-butyl ether,has a high octane number and reduces exhaust pollutants.
    Type: Grant
    Filed: April 28, 1982
    Date of Patent: August 28, 1984
    Assignee: Veba Oel AG
    Inventors: Hartmut Bruderreck, Gunter Deininger, Klaus Gottlieb, Friedel-Heinrich Wehmeier, Manfred Haselhorst
  • Patent number: 4408085
    Abstract: A process for producing sec-butanol and sec-butyl tert-butyl ether from butane comprises: (a) partially isomerizing n-butane to produce a mixture of n-butane and isobutane; (b) catalytically dehydrogenating said butanes to produce a mixture containing at least butene-1, isobutene and butadiene; (c) selectively hydrogenating butadiene and converting butene-1 to butene-2; (d) etherifying isobutene contained in the dehydrogenation reaction mixture with sec-butanol to form a mixture of sec-butyl tert-butyl ether and unreacted hydrocarbons; (e) converting butene-2 from the unreacted hydrocarbon mixture by hydration to produce sec-butanol; (f) recycling said sec-butanol to the etherification step; recovering said sec-butyl tert-butyl ether.
    Type: Grant
    Filed: April 28, 1982
    Date of Patent: October 4, 1983
    Assignee: VEBA OEL AG
    Inventors: Klaus Gottlieb, Wilfried Graf
  • Patent number: 4393250
    Abstract: A process for producing isopropyl alcohol and isopropyl tert-butyl ether from a mixture of light hydrocarbons containing propane and butane, comprises:(a) separating from the mixture of light hydrocarbons a propane fraction and a butane fraction containing at least n-butane;(b) isomerizing at least a portion of the n-butane in the butane fraction from step (a) whereby a hydrocarbon mixture containing at least n-butane and isobutane is formed;(c) catalytically dehydrogenating the isobutane in the hydrocarbon mixture from step (b) whereby a hydrocarbon mixture containing at least isobutene is produced;(d) catalytically dehydrogenating the propane in the propane fraction from step (a) whereby a hydrocarbon mixture containing at least propene is produced;(e) reacting the propene in the hydrocarbon mixture from step (d) with water, whereby a mixture containing hydrocarbons and isopropyl alcohol is formed;(f) reacting the isopropyl alcohol from step (e) with at least part of the isobutene in the hydrocarbon mixture
    Type: Grant
    Filed: April 28, 1982
    Date of Patent: July 12, 1983
    Assignee: Veba Oel AG
    Inventors: Klaus Gottlieb, Hartmut Bruderreck, Friedel-Heinrich Wehmeier