Patents by Inventor Klaus Habenstein

Klaus Habenstein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6114170
    Abstract: The invention relates to a method for determining the ionic strength and/or the specific weight of aqueous liquids and a reagent for this purpose, the composition of the reagent being such that the color change indicating the ionic strength is essentially directly dependent on the specific weight of the liquid to be determined and not on a pH shift.
    Type: Grant
    Filed: October 15, 1997
    Date of Patent: September 5, 2000
    Assignee: Dade Behring Marburg GmbH
    Inventor: Klaus Habenstein
  • Patent number: 5869231
    Abstract: The invention relates to a sampling kit for obtaining, in a rapid and gentle manner, a defined volume of lacrimal fluid for the purpose of reproducibly determining components of the lacrimal fluid.
    Type: Grant
    Filed: October 14, 1997
    Date of Patent: February 9, 1999
    Assignee: Behring Diagnostics GmbH
    Inventors: Jurgen Romisch, Eckhard Schuler, Klaus Habenstein, Jurgen Lindner
  • Patent number: 5858788
    Abstract: Reagent for determining the ionic strength and/or the specific weight of aqueous liquids and a reagent for this purpose, the composition of the reagent being such that the color change indicating the ionic strength is essentially directly dependent on the specific weight of the liquid to be determined and not on a pH shift.
    Type: Grant
    Filed: December 27, 1994
    Date of Patent: January 12, 1999
    Assignee: Behring Diagnostics GmbH
    Inventor: Klaus Habenstein
  • Patent number: 5756359
    Abstract: The present invention relates to reagents and processes for the preparation of diagnostics which use a chromogenic redox detection system and whose chromogenic redox detection system essentially remains unaffected by interference from reducing. compounds in the sample material.
    Type: Grant
    Filed: May 20, 1997
    Date of Patent: May 26, 1998
    Assignee: Behring Diagnostics GmbH
    Inventors: Klaus Habenstein, Dieter Zopf, Winfried Bursch
  • Patent number: 5696001
    Abstract: The invention relates to fluorogenic compounds for the detection of hydrolyzing enzymes and the use of the fluorogenic compounds.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: December 9, 1997
    Assignee: Behringwerke Aktiengesellschaft
    Inventor: Klaus Habenstein
  • Patent number: 5683656
    Abstract: The present invention relates to reagents and processes for the preparation of diagnostics which use a chromogenic redox detection system and whose chromogenic redox detection system essentially remains unaffected by interference from reducing compounds in the sample material.
    Type: Grant
    Filed: February 22, 1996
    Date of Patent: November 4, 1997
    Assignee: Behringwerke Aktiengesellschaft
    Inventors: Klaus Habenstein, Dieter Zopf, Winfried Bursch
  • Patent number: 5648229
    Abstract: The invention relates to fluorogenic compounds for the detection of hydrolyzing enzymes and the use of the fluorogenic compounds.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: July 15, 1997
    Assignee: Behringwerke Aktiengesellschaft
    Inventor: Klaus Habenstein
  • Patent number: 5585247
    Abstract: The invention relates to fluorogenic compounds for the detection of hydrolyzing enzymes and the use of the fluorogenic compounds.
    Type: Grant
    Filed: May 21, 1990
    Date of Patent: December 17, 1996
    Assignee: Behringwerke Aktiengesellschaft
    Inventor: Klaus Habenstein
  • Patent number: 5077200
    Abstract: Chromogenic substrates for the detection of hydrolyzing enzymes, processes for the preparation of these chromogenic substrates and the use of the chromogenic substrates.The quantification of hydrolyzing enzymes for diagnostic purposes has to date been carried out by determination of the amounts of a fluorescent or highly absorbent chromogenic dyestuff liberated in the hydrolytic reaction, detection of which has in part been possible exlusively by instruments or in the neutral to alkaline pH range. After enzymatic hydrolysis, the chromogenic substrates according to the invention lead to highly sensitive and specifically measurable signals regardless of the pH range.Azo dyestuff compounds with the general formulaA--N.dbd.N--B (OR)in which A) and B) have the meanings given in claim 1 andR) is a radical which can be liberated by enzymatic hydrolysis, excluding a carbonyl radical,are provided.After enzymatic hydrolysis, highly sensitively and specifically measurable signals are obtained regardless of the pH range.
    Type: Grant
    Filed: September 28, 1988
    Date of Patent: December 31, 1991
    Assignee: Behringwerke Aktiengesellschaft
    Inventor: Klaus Habenstein
  • Patent number: 4861711
    Abstract: A solid diagnostic device for the quantitative determination of substances of biological affinity in biological fluids is described. A process is also described in which the biological fluid is brought into contact with a specific functional sector of the device, the fluid migrates through several functional sectors situated beside one another and containing suitable reagent components, and one or more substances of biological affinity are detected in such functional sectors which contain, for each substance to be detected, at least one combination partner of biological affinity, attached to a solid phase.
    Type: Grant
    Filed: December 13, 1985
    Date of Patent: August 29, 1989
    Assignee: Behringwerke Aktiengesellschaft
    Inventors: Heinz-Jurgen Friesen, Gerd Grenner, Hans-Erwin Pauly, Helmut Kohl, Klaus Habenstein, Joseph Stark
  • Patent number: 4563421
    Abstract: What are disclosed are polysaccharide derivatives of the formula ##STR1## in which n denotes a number from 100 to 12,500 and R denotes hydrogen, a carboxyalkyl or hydroxyalkyl group with 1 to 5 carbon atoms in the alkyl radical or a detectable molecular group, any combination of the (3n+2) R radicals being possible, but at least one R being a carboxyalkyl or hydroxyalkyl group and at least one R being a detectable molecular group, and a process for their preparation and their use for the determination of endohydrolases, in indicator paper and for the detection of metabolites in biological liquids, are described.
    Type: Grant
    Filed: November 25, 1983
    Date of Patent: January 7, 1986
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Klaus Habenstein, Helmut Kohl
  • Patent number: 4481295
    Abstract: What are disclosed are a method for detecting substances having a peroxidative effect using a substituted or condensed pyridine, and a diagnostic agent containing a pyridine of this kind.
    Type: Grant
    Filed: June 27, 1980
    Date of Patent: November 6, 1984
    Assignee: Behringwerke Aktiengesellschaft
    Inventor: Klaus Habenstein
  • Patent number: 4372746
    Abstract: Rapid diagnostic agent comprising an absorbent carrier matrix, a chromogen, a hydroperoxide, a detergent, an activator and a compound of the formula I ##STR1## or a copolymer containing such a compound, and, if appropriate, another protective colloid. A diagnostic agent of this type can be used in a method for detecting, in body fluids and excreta, peroxidatively active substances.
    Type: Grant
    Filed: July 2, 1981
    Date of Patent: February 8, 1983
    Assignee: Behringwerke Aktiengesellschaft
    Inventor: Klaus Habenstein
  • Patent number: 4184850
    Abstract: A diagnostic agent for the detection of ketones in fluids consisting of an absorbent carrier impregnated with sodium nitroferricyanide, a water-soluble lower amino acid, an alkaline buffer substance, and at least one organic acid, said organic acid serving to form a stabilizing environment around the sodium nitroferricyanide. The improved diagnostic agent may be produced by impregnating the carrier in a first step with an aqueous solution of the buffer substance and the amino acid, in a second step with a solution of an organic acid in an organic solvent and in a third step with a solution of sodium nitroferricyanide and a water-soluble organic acid in an organic solvent.
    Type: Grant
    Filed: July 20, 1978
    Date of Patent: January 22, 1980
    Assignee: Behringwerke Aktiengesellschaft
    Inventor: Klaus Habenstein
  • Patent number: RE38688
    Abstract: A solid diagnostic device for the quantitative determination of substances of biological affinity in biological fluids is described. A process is also described in which the biological fluid is brought into contact with a specific functional sector of the device, the fluid migrates through several functional sectors situated beside one another and containing suitable reagent components, and one or more substances of biological affinity are detected in such functional sectors which contain, for each substance to be detected, at least one combination partner of biological affinity, attached to a solid phase.
    Type: Grant
    Filed: March 30, 2001
    Date of Patent: January 18, 2005
    Assignee: Dade Behring Marburg GmbH
    Inventors: Heinz-Jürgen Friesen, Gerd Grenner, Hans-Erwin Pauly, Helmut Kohl, Klaus Habenstein, Joseph Stärk
  • Patent number: RE37437
    Abstract: A solid diagnostic device for the quantitative determination of substances of biological affinity in biological fluids is described. A process is also described in which the biological fluid is brought into contact with a specific functional sector of the device, the fluid migrates through several functional sectors situated beside one another and containing suitable reagent components, and one or more substances of biological affinity are detected in such functional sectors which contain, for each substance to be detected, at least one combination partner of biological affinity, attached to a solid phase.
    Type: Grant
    Filed: October 18, 1995
    Date of Patent: November 6, 2001
    Assignee: Dade Behring Marburg, GmbH
    Inventors: Heinz-Jürgen Friesen, Gerd Grenner, Hans-Erwin Pauly, Helmut Kohl, Klaus Habenstein, Joseph Stärk