Patents by Inventor Klaus-Heinrich Seifart

Klaus-Heinrich Seifart has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleic acid constructs containing hybrid promoters for use in gene therapy
    Publication number: 20030187245
    Abstract: Nucleic acid constructs containing hybrid promoters for use in gene therapy and genetic manipulation. The invention relates to a nucleic acid construct for the precise, regulated expression of genes in host cells, which construct exhibits at least one mutation which inhibits the proper expression of the expressed gene and exhibits at least one additional second mutation which relieves the inhibition due to the first mutation, to an isolated cell which harbors the nucleic acid construct, and to the use of the nucleic acid construct for preparing pharmaceuticals and for treating diseases with excessive cell proliferation.
    Type: Application
    Filed: April 7, 2003
    Publication date: October 2, 2003
    Inventors: Klaus-Heinrich Seifart, Rolf Mueller, Hans-Harald Sedlacek
  • Nucleic acid constructs containing hybrid promoters
    Patent number: 6576758
    Abstract: Nucleic acid constructs containing hybrid promoters for use in gene therapy and genetic manipulation. The invention relates to a nucleic acid construct for the precise, regulated expression of genes in host cells, which construct exhibits at least one mutation which inhibits the proper expression of the expressed gene and exhibits at least one additional second mutation which relieves the inhibition due to the first mutation, to an isolated cell which harbors the nucleic acid construct, and to the use of the nucleic acid construct for preparing pharmaceuticals and for treating diseases with excessive cell proliferation.
    Type: Grant
    Filed: September 24, 1997
    Date of Patent: June 10, 2003
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Klaus-Heinrich Seifart, Rolf Mueller, Hans-Harald Sedlacek