Patents by Inventor Klaus Hirzel

Klaus Hirzel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200140569
    Abstract: The present disclosure relates to specific binding agents binding to different PIVKA-II forms as compared to antibodies known so far in the art. The present disclosure also relates to methods of using the specific binding agents to detect the presence of PIVKA-II.
    Type: Application
    Filed: January 13, 2020
    Publication date: May 7, 2020
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Bernhard Eckert, Michael Gerg, Johann Karl, Martin Kaufmann, Julia Riedlinger, Magdelena Swiatek-de Lange, Lars Hillringhaus, Klaus Hirzel, Marcus-Rene Lisy
  • Publication number: 20190324024
    Abstract: The present invention relates to a monoclonal antibody capable of binding to biotin. In one embodiment the monoclonal antibody according to the invention also does not bind to a biotin moiety on a biotinylated molecule, wherein the biotin moiety is attached to the molecule via the carbon atom of the carboxyl function of the valeric acid moiety of biotin. Also disclosed is a method for generation of an antibody as disclosed herein. The monoclonal antibody according to the invention is of specific use in a method for measuring an analyte in a sample, wherein a (strept)avidin/biotin pair is used to bind a biotinylated analyte specific binding agent to a (strept)avidin coated solid phase.
    Type: Application
    Filed: June 24, 2019
    Publication date: October 24, 2019
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Michael Gerg, Klaus Hirzel, Caroline Dorothea Hojer, Erasmus Huber, Hans-Peter Josel, Thomas Meier, Michael Schraeml, Leopold Von Proff
  • Publication number: 20190324025
    Abstract: The present invention relates to a monoclonal antibody capable of binding to biotin. In one embodiment the monoclonal antibody according to the invention also does not bind to a biotin moiety on a biotinylated molecule, wherein the biotin moiety is attached to the molecule via the carbon atom of the carboxyl function of the valeric acid moiety of biotin. Also disclosed is a method for generation of an antibody as disclosed herein. The monoclonal antibody according to the invention is of specific use in a method for measuring an analyte in a sample, wherein a (strept)avidin/biotin pair is used to bind a biotinylated analyte specific binding agent to a (strept)avidin coated solid phase.
    Type: Application
    Filed: June 24, 2019
    Publication date: October 24, 2019
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Michael Gerg, Dieter Heindl, Lars Hillringhaus, Klaus Hirzel, Caroline Dorothea Hojer, Florian Huber, Hans-Peter Josel, Thomas Meier, Michael Schraeml, Edgar Voss
  • Publication number: 20190309091
    Abstract: The present invention relates to a monoclonal antibody capable of binding to biotin. In one embodiment the monoclonal antibody according to the invention also does not bind to a biotin moiety on a biotinylated molecule, wherein the biotin moiety is attached to the molecule via the carbon atom of the carboxyl function of the valeric acid moiety of biotin. Also disclosed is a method for generation of an antibody as disclosed herein. The monoclonal antibody according to the invention is of specific use in a method for measuring an analyte in a sample, wherein a (strept)avidin/biotin pair is used to bind a biotinylated analyte specific binding agent to a (strept)avidin coated solid phase.
    Type: Application
    Filed: June 24, 2019
    Publication date: October 10, 2019
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Michael Gerg, Lars Hillringhaus, Klaus Hirzel, Caroline Dorothea Hojer, Hans-Peter Josel, Christoph Seidel, Michael Schraeml, Leopold Von Proff
  • Publication number: 20170131723
    Abstract: The invention relates to a device for controlling the operation of a spreading apparatus of a spreading vehicle (1) for winter road maintenance, comprising a data transmission apparatus (100), which is provided in the spreading vehicle and which is designed to establish a wireless data connection, and which is designed to receive forecast data regarding weather conditions and/or transportation route conditions from a server, in particular via the Internet, an apparatus (101) for detennining transportation route conditions, which is mounted in or on the spreading vehicle and is designed to detennine surface parameters of a transportation route, and a control unit (102), which is designed to receive the forecast data from the data transmission apparatus (100) and to process said forecast data and to control the operation of the spreading apparatus on the basis of the processed forecast data and the determined surface parameters.
    Type: Application
    Filed: June 16, 2014
    Publication date: May 11, 2017
    Inventor: Klaus Hirzel