Patents by Inventor Klaus Irmscher

Klaus Irmscher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4788215
    Abstract: Halogenohydroxyflavones ##STR1## in which R is alkyl having 1-3 C atoms,X is F, Cl, Br or I, andm, n and p are each 1, 2 or 3,and their esters with sulfuric acid and phosphoric acid, and the salts of these compounds, are suitable for the treatment of hyperthyroidism.
    Type: Grant
    Filed: September 18, 1987
    Date of Patent: November 29, 1988
    Assignee: Merck Patent Gesellschaft mit Beschrankter Haftung
    Inventors: Josef Kramer, Klaus Irmscher, Helmut Prucher, Rolf-Dieter Hesch
  • Patent number: 4713465
    Abstract: Halogenohydroxyflavones ##STR1## in which R is alkyl having 1-3 C atoms,X is F, Cl, Br or I, andm, n and p are each 1, 2 or 3,and their esters with sulfuric acid and phosphoric acid, and the salts of these compounds, are suitable for the treatment of hyperthyroidism.
    Type: Grant
    Filed: November 26, 1985
    Date of Patent: December 15, 1987
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Josef Kramer, Klaus Irmscher, Helmut Prucher, Rolf-Dieter Hesch
  • Patent number: 4680288
    Abstract: Sulfur-containing 6-ketoprostaglandins of the formula I ##STR1## in which D is a bond, alkylene having 1-3 C atoms, cis-alkenylene having 2-5 C atoms or alkinylene having 2-5 C atoms,R.sup.1 is H, alkyl having 1-4 C atoms, aryl having 6-12 C atoms or --C.sub.6 H.sub.4 NHCOC.sub.6 H.sub.5,R.sup.2 is alkyl having 1-7 C atoms, alkyl having 1-7 C atoms which is substituted by halogen, cycloalkyl having 5-6 C atoms, cycloalkyl having 5-6 C atoms which is substituted by alkyl having 1-4 C atoms, phenyl, phenyl which is substituted by F, Cl, Br, alkyl having 1-4 C atoms, OH, OCH.sub.3 or CF.sub.3, pyridyl, naphthyl, thienyl or, if D is alkylene having 1-3 C atoms, also is alkoxy having 1-4 C atoms, alkylthio having 1-4 C atoms, phenoxy or phenoxy which is substituted by F, Cl, Br, alkyl having 1-4 C atoms, OH, OCH.sub.3 or CF.sub.3,R.sup.3 and R.sup.
    Type: Grant
    Filed: January 18, 1985
    Date of Patent: July 14, 1987
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Klaus Irmscher, Hans-Eckart Radunz, Ernst Schulze, Bernhard Riefling
  • Patent number: 4654350
    Abstract: Imidazo(4,5-c)pyridines of the formula ##STR1## wherein X is O, S or NH;Y is --NR.sup.2 --CH.dbd.N-- or --N.dbd.CH--NR.sup.2 --;R.sup.1 is 1-benzothienylmethyl, naphthylmethyl, or benzyl which is mono- or di-substituted by F, Cl, NO.sub.2, CF.sub.3 or a combination thereof, and;R.sup.2 is alkyl of 1-4 C atoms or cyclopropylmethyl,or a physiologically acceptable acid addition salt thereof,have valuable pharmacological activity, e.g., as GABA agonists.
    Type: Grant
    Filed: June 12, 1986
    Date of Patent: March 31, 1987
    Assignee: Merck Patent Gesellschaft Mit Beschrankter Haftung
    Inventors: Klaus Irmscher, Otto Saiko, Klaus-Otto Minck, Hans-Peter Wolf
  • Patent number: 4590180
    Abstract: Adenosine derivatives of formula I ##STR1## wherein X is F, Cl or Br and n is 1 or 2, and their physiologically acceptable acid addition salts, are valuable psychopharmacological agents.
    Type: Grant
    Filed: April 22, 1983
    Date of Patent: May 20, 1986
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Klaus Irmscher, Rochus Jonas, Jurgen Uhl, Ernst Schorscher
  • Patent number: 4514405
    Abstract: Adenosine derivatives of formula I ##STR1## wherein R is H, F, Cl, Br or CF.sub.3, and their physiologically acceptable acid addition salts, are valuable anticonvulsants.
    Type: Grant
    Filed: January 23, 1984
    Date of Patent: April 30, 1985
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Klaus Irmscher, Jurgen Uhl
  • Patent number: 4016281
    Abstract: Tetralone and indanone compounds of the formula ##STR1## wherein R.sup.1 is H, OH, alkoxy of 1-4 carbon atoms, cycloalkoxy of 3-6 carbon atoms, F, Cl, Br, NO.sub.2, monoalkylamino or dialkylamino, wherein each alkyl is of 1-4 carbon atoms, alkanoyloxy of 1-6 carbon atoms or alkanoylamino of 1-4 carbon atoms; R.sup.2 is OH or alkoxy of 1-4 carbon atoms or R.sup.1 and R.sup.2 collectively are methylenedioxy; R.sup.3 is H or CH.sub.3 ; Ar is phenyl or phenyl substituted by up to 5 of alkyl of 1-4 carbon atoms, alkoxy of 1-4 carbon atoms, F, Cl, Br or CF.sub.3 ; n is 1 or 2, and physiologically acceptable acid addition salts thereof, are central nervous system depressants.
    Type: Grant
    Filed: February 18, 1976
    Date of Patent: April 5, 1977
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Rochus Jonas, Jurgen Uhl, Helmut Muller-Calgan, Klaus Irmscher