Patents by Inventor Klaus Joachin Van Leyen

Klaus Joachin Van Leyen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitors of human 12/15-lipoxygenase
    Patent number: 10287279
    Abstract: A systematic screening has revealed a family of compounds that exhibit inhibitory effects on 12/15-lipoxygenase. Accordingly, the present invention relates to the use of these compounds for the inhibition of 12/15-lipoxygenase and for the treatment of a condition involving 12/15-lipoxygenase. Exemplary conditions include, but are not limited to, stroke, periventricular leukomalacia, cardiac arrest with resuscitation, atherosclerosis, Parkinson's disease, Alzheimer's disease, and breast cancer.
    Type: Grant
    Filed: February 19, 2016
    Date of Patent: May 14, 2019
    Assignees: THE CHILDREN'S HOSPITAL CORPORATION, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services
    Inventors: Klaus Joachin Van Leyen, Theodore R. Holman, David J. Maloney, Ajit Jadhav, Anton Simeonov, Ganesha Rai