Patents by Inventor Klaus Lehmann
Klaus Lehmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20010022972Abstract: A non-toxic, edible, enteric film coating, dry powder composition for use in making an aqueous enteric suspension which may be used in coating pharmaceutical tablets comprises a) an acrylic resin, said resin comprising i) from 20 to 85 percent by weight of at least one alkyl acrylate or alkyl methacrylate moiety, ii) from 80 to 15 percent by weight of at least one vinyl or vinylidene moiety having a carboxylic acid group capable of salt formation, and iii) from 0 to 30 percent by weight of at least one other vinyl or vinylidene moiety copolymerizable with i) and ii), b) an alkalizing agent capable of reacting with the acrylic resin such that, after reaction, 0.1 to 10 mole percent of the acidic groups in 1a-ii) are present in the salt form, and c) a detacktifier.Type: ApplicationFiled: January 19, 2001Publication date: September 20, 2001Inventors: Ramireddy Chittamuru, George Reyes, Thomas P. Farrell, Charles F. Vesey, Dev K. Mehra, Hans-Ulrich Petereit, Klaus Lehmann
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Patent number: 6069975Abstract: A signal is processed for recognize an irregularity in the signal. First, an orthogonal imaginary signal corresponding to the signal to be processed is formed. This is followed by a transformation step, which is then followed by a differentiation step. The signal thus processed shows the irregularity particularly clearly, so that the irregularity can be isolated, selected and detected. Preferred fields of application for the present method and corresponding devices are in the medical field, information technology, and signal treatment in network engineering, in particular low, medium, and high voltage engineering.Type: GrantFiled: November 16, 1998Date of Patent: May 30, 2000Assignee: Siemsn AktiengesellschaftInventors: Klaus Lehmann, Peter Kartmann, Christian Heilmann
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Patent number: 5730999Abstract: A dermal therapeutic system which exhibits a prolonged release of a drug comprising at least one pharmaceutical agent combined with poly(meth)acrylates in the form of at least one layer of the therapeutic system, the poly(meth)acrylates being a mixture, which is produced from a melt, comprising (1) at least one (meth)acrylic polymer containing functional groups and (2) at least one (meth)acrylic polymer which regulates the flow behavior of the poly(meth)acrylate mixture and which contains no functional groups or only insignificant amounts of functional groups.Type: GrantFiled: May 17, 1996Date of Patent: March 24, 1998Assignee: Roehm GmbH Chemische FabrikInventors: Klaus Lehmann, Hans-Ulrich Petereit, Manfred Assmus
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Aqueous dispersions containing carboxylic acids and/or resinic acids for deinking printed wastepaper
Patent number: 5725730Abstract: The invention relates to aqueous dispersions containing A. C.sub.6-22 carboxylic acids and/or resinic acids and B. C.sub.6-22 oxoalcohols alkoxylated with 2 to less than 6 mol C.sub.2-4 alkylene oxides for deinking printed wastepaper.Type: GrantFiled: October 24, 1994Date of Patent: March 10, 1998Assignee: Gruenau IllertissenInventors: Heinz-Gerd Smolka, Klaus Lehmann, Hans Hawel, Dieter Schraml, Klaus Hornfeck -
Patent number: 5705189Abstract: Thermoplastic materials which comprise a copolymer of(A) 16 to 40 wt % of acrylic and/or methacrylic acid;(B) 30 to 80 wt % of methyl acrylate; and(C) 0 to 40 wt % of another alkyl ester of acrylic and/or methacrylic acid and perhaps conventional auxiliaries for drug coatings are suitable for the production of drug coatings which are soluble in intestinal juices, such as tablet coatings, dies, films, capsules, or multipart dosage units.Type: GrantFiled: August 31, 1995Date of Patent: January 6, 1998Assignee: Roehm GmbH Chemische FabrikInventors: Klaus Lehmann, Werner Hoess
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Patent number: 5644011Abstract: Coatings and binders for pharmaceutical forms containing a copolymerizate, wherein the copolymerizate is made up of:A) 10 to 25 wt % methacrylic acid;B) 40 to 70 wt % methyl acrylate; andC) 20 to 40 wt % methyl methacrylate; based on the total weight of the copolymerizate.Type: GrantFiled: August 25, 1995Date of Patent: July 1, 1997Assignee: Roehm GmbH Chemical FactoryInventors: Klaus Lehmann, Thomas Sufke
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Patent number: 5422121Abstract: Coating agents comprising a liquid phase, a polysaccharide decomposable in the colon, such as locust bean gum or guar gum, and a film forming polymer preferably having hydrophilic groups, which agent, when used for the coating of oral dosage unit forms, give coatings of high mechanical strength which are first decomposed under the influence of glycosidic enzymes in the colon; oral dosage unit forms incorporating such agents.Type: GrantFiled: August 16, 1993Date of Patent: June 6, 1995Assignee: Rohm GmbHInventors: Klaus Lehmann, Ottilie E. E. Kehr-Dreher, Giuseppe Di Pascale
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Patent number: 5362363Abstract: The invention relates to aqueous dispersions of alkaline earth metal soaps and/or alkaline earth metal resin soaps for deinking printed wastepaper in which the dispersions containA. alkaline earth metal salts of C.sub.6-22 carboxylic acids and/or resinic acids andB. C.sub.6.22 oxoalcohols alkoxylated with 2 to less than 6 mol C.sub.2-4 alkylene oxides and alkali metal and/or alkaline earth metal alumimo silicates corresponding to general formula I0.7-1.5 cat.sub.2/n O.Al.sub.2 O.sub.3.0.8-6 SiO.sub.2in which cat represents alkali metal and/or alkaline earth metal cations and n is the valency of the alkali metal and/or alkaline earth metal cations.Type: GrantFiled: April 20, 1992Date of Patent: November 8, 1994Assignee: Chemische Fabrik Gruenau GmbHInventors: Heinz-Gerd Smolka, Klaus Lehmann, Hans Hawel, Dieter Schraml, Klaus Hornfeck
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Patent number: 5342646Abstract: What is disclosed is a method for preparing carrier systems, adaptable to the covalent bonding thereto of biologically active materials, consisting of a known solid support material having a surface coated with a polymer containing functional groups suitable for covalent bonding, by coating the support material with a film-forming polymer dispersion and a non-film-forming polymer dispersion, suitably in admixture, at least one of the two polymer dispersions containing a polymer having functional groups suitable for covalent bonding with a biologically active material.Type: GrantFiled: November 19, 1992Date of Patent: August 30, 1994Assignee: Rohm GmbHInventors: Wolfgang Kleese, Dieter Kraemer, Hans-Ulrich Petereit, Klaus Lehmann, Werner Siol
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Patent number: 5292522Abstract: A water insoluble lipophilic emulsifier having a hydrophile-lipophile balance (HLB) of 3.5 to 7, added to an aqueous dispersion containing a polymer comprising acrylic acid, methacrylic acid, their alkyl esters, and/or their alkylaminoalkyl esters, acts as a lubricant and parting agent when the resulting mixture is used for coating pharmaceutical dosage forms and prevents the pharmaceutical dosage forms being coated from sticking to one another and to the walls of the coating apparatus used.Type: GrantFiled: December 28, 1992Date of Patent: March 8, 1994Assignee: Rohm GmbHInventors: Hans-Ulrich Petereit, Manfred Assmus, Klaus Lehmann
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Patent number: 5177451Abstract: A unity gain amplifier of the diamond follower type provides the combination of negligible input offset voltage, high slew rate, and high bandwidth by providing first and second opposite polarity current mirror circuits which respond to currents flowing through first and second input transistors to boost current available to charge parasitic capacitances during fast rise times and fast fall times of an input pulse. The rapid charging and discharging of the parasitic capacitances eliminates degradation in the rise and fall times of an output pulse produced by the unity gain amplifier. The gains of the first and second current mirror circuits have values that result in critically damped high frequency response of the unity gain amplifier in response to high speed transistions of the input signal. Darlington output stages are used to avoid frequency response peaking due to current gain rolloff of the output transistors at high currents and high frequencies.Type: GrantFiled: July 26, 1991Date of Patent: January 5, 1993Assignee: Burr-Brown CorporationInventor: Klaus Lehmann
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Patent number: 5175285Abstract: A conversion product of polysuccinimide useful as coating material for medicinal preparations and foodstuffs having the structure: ##STR1## wherein A is hydrogen or a straight or branched alkyl or alkylene group of 1 to 8 carbon atoms, optionally substituted by cycloaliphatic or aromatic groups, wherein the cyclic substituent can also contain heteroatoms, or by R--O--, ##STR2## or R.sub.3 R.sub.4 N groups, wherein R, R.sub.1, R.sub.2, R.sub.3, and R.sub.4 are hydrogen or branched alkyl or cycloalkyl groups each of which may contain oxygen and nitrogen atoms in the chain or in the ring of 1 to 10 carbon atoms;B is hydrogen or straight or branched chain alkyl or alkenyl, and is the same or different from A;D is hydrogen, NH.sub.4, ##STR3## wherein A and B have the aforementioned meanings, or an alkali metal ion; anda is 0.2 to 1 and b is 0.8 to 0.Type: GrantFiled: July 5, 1990Date of Patent: December 29, 1992Assignee: Rohm GmbH Chemische FabrikInventors: Klaus Lehmann, Rdiger Jelitte, Joachim Knebel
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Patent number: 5142062Abstract: A method of manufacturing polysuccinimides with molecular weights in the range 100,000 to about 200,000 by polycondensation of aspartic acid, with phosphoric acids as condensation agents, in at least two process stages, at temperatures of 100.degree.-250.degree. C. and under reduced pressure, where in the second stage the mixture containing aspartic acid and phosphoric acid undergoes subsequent condensation following comminution.Type: GrantFiled: July 5, 1991Date of Patent: August 25, 1992Assignee: Rohm GmbH Chemische FabrikInventors: Joachim Knebel, Klaus Lehmann
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Patent number: 5003269Abstract: A unity gain amplifier of the Diamond follower type provides the combination of negligible input offset voltage, high slew rate, and high bandwidth by providing first and second opposite polarity current mirror circuits which respond to currents flowing through first and second input transistors to boost current available to charge parasitic capacitances during fast rise times and fast fall times of an input pulse. The rapid charging and discharging of the parasitic capacitances eliminates degradation in the rise and fall times of an output pulse produced by the unity gain amplifier.Type: GrantFiled: May 12, 1989Date of Patent: March 26, 1991Assignee: Burr-Brown CorporationInventor: Klaus Lehmann
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Patent number: 4971656Abstract: A flotation process for the de-inking of printed waste-paper by treating the paper pulp in the pulper at alkaline pH-values by means of alkali silicate, oxidative bleaches and separating the loosened printing-ink particles from the fibrous material suspension by flotation, in which protein fatty acid condensates are added finely distributed, possibly together with dispersing agents, in a solution or dispersion which is fluid at normal temperature.Type: GrantFiled: March 31, 1989Date of Patent: November 20, 1990Assignee: Chemische Fabrik Gruenau GmbHInventors: Klaus Lehmann, Andreas Domsch, Hans Hawel, Gregor Schuster
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Patent number: 4959123Abstract: Process for deinking printed waste paper by treatment of the paper pulp in a pulper at alkaline pH values using alkali silicate, oxidative bleaches, higher fatty and/or resinic acids and dispersants and separation of the detached printing ink particles from the fiber suspension by flotation, the fatty and/or resinic acids being used in the form of their alkaline earth metal salts in fine distribution together with dispersants in an oil-in-water dispersion which is liquid at normal temperature.Type: GrantFiled: February 2, 1988Date of Patent: September 25, 1990Assignee: Chemische Fabrik Gruenau GmbHInventors: Klaus Lehmann, Andreas Domsch, Hans Hawel
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Patent number: 4816558Abstract: A method for obtaining redispersible powders of a copolymer having a dynamic glass transition temperature, T.sub.max, below 150.degree. C., by spray drying an aqueous dispersion thereof having a minimum film forming temperature, MFT, using an inlet temperature T.sub.i and an outlet temperature T.sub.o such that MFT<T.sub.i <T.sub.max and MFT<T.sub.o <65.degree. C.Type: GrantFiled: July 27, 1987Date of Patent: March 28, 1989Assignee: Rohm GmbHInventors: Hubert Rauch, Wolfgang Klesse, Klaus Lehmann, Theodor Mager
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Patent number: 4737357Abstract: Aqueous dispersions of a water-swellable but water-insoluble polymer formed between a quaternary ammonium monomer and a nonionic monomer; methods for making such dispersions by dispersing said copolymers, in the form of a powder, in water; methods for coating pharmaceutical cores, powders, or granules with such dispersions; and coated pharmaceutical products made by such methods.Type: GrantFiled: May 29, 1987Date of Patent: April 12, 1988Assignee: Rohm GmbHInventors: Klaus Lehmann, Dieter Dreher, Wolfgang Weisbrod
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Patent number: 4727061Abstract: Pharmaceutical preparations having diuretic activity and comprising a peptide of the formula ##STR1## wherein (a) R.sub.1 and R.sub.2 are hydrogen and R.sub.3 is --OH, or ##STR2## or Y, or wherein (b) R.sub.1 is hydrogen, R.sub.2 is CH.sub.2 OH or ##STR3## and R.sub.3 is --OH or Y, or wherein (c) R.sub.1 is --CH.sub.2 OH and R.sub.2 is hydrogen or ##STR4## and R.sub.3 is --OH or Y, or wherein (d) R.sub.1 is ##STR5## R.sub.2 is hydrogen or --CH.sub.2 OH and R.sub.3 is --OH, --NHCH.sub.2 COOH, or Y, andwhereinX is hydrogen, methyl, prolyl, or an N-protective group, andY is --NH.sub.2, --OR.sub.4, wherein R.sub.Type: GrantFiled: December 6, 1985Date of Patent: February 23, 1988Assignee: Rohm GmbHInventors: Herbert J. Kramer, Klaus Lehmann, Colin Liddiard
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Patent number: RE35200Abstract: Coated pharmaceutical dosage forms which are resistant to gastric juice and release their active ingredient rapidly at a predetermined pH value in the range from pH 5 to pH 8 are obtained in accordance with the invention by coating pharmaceutical dosage forms with an aqueous dispersion containing dispersed latex particles of a first polymer which contains carboxyl groups and is water soluble between pH 5 and pH 8 and of a second water insoluble film forming polymer, in a weight ratio between 60:40 and 5:95.Type: GrantFiled: September 16, 1993Date of Patent: April 2, 1996Assignee: Rohm GmbHInventors: Klaus Lehmann, Dieter Dreher, Harry Goetz