Patents by Inventor Klaus Opitz

Klaus Opitz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8207159
    Abstract: The invention relates to the use of galanthamine, as free base or as acid addition salt, for the treatment of cerebral, central nervous or psychiatric symptoms, defunctionalization manifestations or disorders occurring through intake of psychotropic substances as a consequence of occasional or chronic abuse of addictive substances, intoxicants or medicines, or as side effects of the use, especially repeated or prolonged, as intended of medicaments, or as an effect of use, in particular repeated or prolonged, not as intended of medicaments, or as a result of acute poisoning by psychotropic toxic substances, or as a result of chronic exposure to toxic substances with a psychotropic effect in humans or other vertebrates.
    Type: Grant
    Filed: April 18, 2002
    Date of Patent: June 26, 2012
    Assignee: HF Arzneimittelforschung GmbH
    Inventors: Klaus Opitz, Joachim Moormann, Thomas Hille, Frank Becher
  • Publication number: 20070155774
    Abstract: Orally administrable film-shaped medicaments which contain the active substance deoxypeganine or/and a deoxypeganine derivative. The medicaments can be used for transmucosal administration of active substances.
    Type: Application
    Filed: November 8, 2004
    Publication date: July 5, 2007
    Inventors: Joachim Moormann, Klaus Opitz, Hans-Rainer Hoffmann
  • Publication number: 20070072947
    Abstract: Deoxypeganine in the form of a free base or in the form of an acid addition salt, or a derivative of deoxypeganine as long as the derivative is simultaneously an inhibitor of acetylcholinesterase and of monoamine oxidase. The deoxypeganine can be used for producing a medicament for treating a schizophrenic psychosis.
    Type: Application
    Filed: November 8, 2004
    Publication date: March 29, 2007
    Applicant: HF ARNEIMITTELFORSCHUNG GMBH
    Inventors: Joachim Moormann, Klaus Opitz
  • Publication number: 20060199866
    Abstract: An active substance combination comprising deoxypeganine or of one of its pharmaceutically acceptable derivatives and mecamylamine or one of its pharmaceutically acceptable derivatives. The active substance combination serves to produce a medicament for the treatment of alcohol abuse and/or alcohol dependence.
    Type: Application
    Filed: April 16, 2004
    Publication date: September 7, 2006
    Inventors: Joachim Moormann, Klaus Opitz, Hilke Winterhoff
  • Publication number: 20060079500
    Abstract: The present invention relates to a medicament for treating addiction craving which is characterized in that the medicament consists of a combination of two administration forms, one of the administration forms continuously releasing at least one modulator of nicotinic receptors and the other administration form enabling a rapid entry of galanthamine into the central nervous system, as well as a two-stage method for the therapy of substance craving through modulation of neuronal nicotinic receptors, wherein a permanent treatment with a pharmaceutical administration form which continuously delivers a modulator of nicotinic receptors is supplemented upon the appearance of a strong craving for a substance by administering galanthamine or a pharmacologically acceptable salt thereof by means of an administration form which enables rapid entry of this modulator into the central nervous system.
    Type: Application
    Filed: July 25, 2003
    Publication date: April 13, 2006
    Applicant: HF PHARMACEUTICAL INC.
    Inventors: Joachim Moormann, Klaus Opitz, Hermann Mucke
  • Publication number: 20040192683
    Abstract: The present invention relates to an active ingredient combination composed of at least one modulator of the cholinergic system with at least one substance having antiexcitatory activity for pharmacological addictive substance or intoxicant therapy, in particular of alcoholism.
    Type: Application
    Filed: December 11, 2003
    Publication date: September 30, 2004
    Inventors: Joachim Moormann, Hermann Mucke, Klaus Opitz
  • Publication number: 20040167145
    Abstract: The present invention relates to an active ingredient combination composed of at least one modulator of the cholinergic system with at least one substance blocking central opioid receptors for the pharmacological treatment of nicotine dependence.
    Type: Application
    Filed: March 15, 2004
    Publication date: August 26, 2004
    Inventors: Klaus Opitz, Joachim Moormann, Hermann Mucke
  • Publication number: 20040132751
    Abstract: The invention relates to the use of deoxypeganine, as free base or as acid addition salt, for the treatment of cerebral, central nervous or psychiatric symptoms, defunctionalization manifestations or disorders occurring through intake of psychotropic substances as a consequence of occasional or chronic abuse of addictive substances, intoxicants or medicines, or as side effects of the use, especially repeated or prolonged, as intended of medicaments, or as an effect of use, in particular repeated or prolonged, not as intended of medicaments, or as a result of acute poisoning by psychotropic toxic substances, or as a result of chronic exposure to toxic substances with a psychotropic effect in humans or other vertebrates.
    Type: Application
    Filed: December 24, 2003
    Publication date: July 8, 2004
    Inventors: Klaus Opitz, Joachim Moormann, Thomas Hille, Frank Becher
  • Publication number: 20040116406
    Abstract: The invention relates to the use of galanthamine, as free base or as acid addition salt, for the treatment of cerebral, central nervous or psychiatric symptoms, defunctionalization manifestations or disorders occurring through intake of psychotropic substances as a consequence of occasional or chronic abuse of addictive substances, intoxicants or medicines, or as side effects of the use, especially repeated or prolonged, as intended of medicaments, or as an effect of use, in particular repeated or prolonged, not as intended of medicaments, or as a result of acute poisoning by psychotropic toxic substances, or as a result of chronic exposure to toxic substances with a psychotropic effect in humans or other vertebrates.
    Type: Application
    Filed: October 20, 2003
    Publication date: June 17, 2004
    Inventors: Klaus Opitz, Joachim Moormann, Thomas Hille, Frank Becher
  • Patent number: 6627631
    Abstract: Desoxypeganine and its pharmaceutically acceptable acid addition salts can be used in the treatment of alcoholism. Said substances are administered preferably in a continuos and controlled manner. The pharmaceutical administration form enables controlled release, e.g. for oral, transdermal or another route of parenteral administration.
    Type: Grant
    Filed: July 25, 2001
    Date of Patent: September 30, 2003
    Assignees: LTS Lohmann Therapie-Systeme AG, He Arzneimittelforschung GmbH
    Inventors: Bodo Asmussen, Thomas Hille, Hans-Rainer Hoffmann, Klaus Opitz
  • Patent number: 6599511
    Abstract: Desoxypeganine and its pharmaceutically acceptable acid addition salts can be used in the treatment of drug addiction or drug dependence. Said substances are administered preferably in a continuos and controlled manner. The pharmaceutical administration form enables controlled release, e.g. for oral transdermal or another route of parenteral administration.
    Type: Grant
    Filed: October 17, 2001
    Date of Patent: July 29, 2003
    Assignees: LTS Lohmann Therapie-Systeme AG, HF Aezneimittelforschung GmbH
    Inventors: Bodo Asmussen, Thomas Hille, Hans-Rainer Hoffmann, Klaus Opitz
  • Patent number: 6548510
    Abstract: Desoxypeganine and its pharmaceutically acceptable acid addition salts are useful in treating nicotine dependence.
    Type: Grant
    Filed: July 19, 2001
    Date of Patent: April 15, 2003
    Assignees: LTS Lohmann Therapie Systeme AG, HF Arzneimittelforschung GmbH
    Inventors: Bodo Asmussen, Thomas Hille, Hans-Rainer Hoffmann, Klaus Opitz
  • Patent number: 6436937
    Abstract: The invention relates to a device and method for the treatment of Alzheimer's dementia with desoxypeganine and/or a pharmaceutically acceptable acid addition salt of desoxypeganine.
    Type: Grant
    Filed: August 16, 2001
    Date of Patent: August 20, 2002
    Assignee: LTS Lohman-Therapie Systeme AG
    Inventors: Bodo Asmussen, Thomas Hille, Hans-Rainer Hoffmann, Klaus Opitz
  • Patent number: 5519017
    Abstract: Galanthamine and the pharmaceutically suitable acid addition salts thereof can be used for the treatment of alcoholism; these compounds are released from adequate pharmaceutic formulations which are administered, e.g., orally, transdermally, or otherwise parenterally, in a continuous and controlled manner.
    Type: Grant
    Filed: May 5, 1994
    Date of Patent: May 21, 1996
    Assignees: LTS Lohmann Therapie-Systeme GmbH + Co. KG, Hefa-Frenon Arzneimittel GmbH & Co. KG
    Inventor: Klaus Opitz
  • Patent number: 4918076
    Abstract: A method of treating a patient afflicted with alcohol addiction which comprises administering to such patient an amount effective therefor of a dihydropyridine of the formula ##STR1## in which R.sup.1 is one or two substituents independently selected from the group consisting of nitro, halogen, trifluoromethyl and OCHF.sub.2,R.sup.2 and R.sup.3 each independently is alkyl with 1 to 12 carbon atoms optionally substituted by alkoxy with 1 to 4 C atoms, hydroxyl, halogen or N-methyl-N-benzylamino, andR.sup.4 is cyano or alkyl with 1 to 4 carbon atoms optionally substituted by hydroxyl or halogen.
    Type: Grant
    Filed: February 22, 1989
    Date of Patent: April 17, 1990
    Assignee: Troponwerke GmbH & Co. KG.
    Inventors: Klaus Opitz, Jorg Traber
  • Patent number: 4895848
    Abstract: A method for the treatment of alcoholism and medicaments used for such treatment wherein patients receive an effective amount of a 2-pyrimidinyl-1-piperazine derivative of the formula ##STR1## in which n represents one of the numbers 2, 3, 4, 5 or 6, andR represents ##STR2## in which R.sup.1, R.sup.2 and R.sup.3 each independently denote hydrogen or lower alkyl, or salts thereof.
    Type: Grant
    Filed: August 3, 1988
    Date of Patent: January 23, 1990
    Assignee: Troponwerke GmbH & Co. KG.
    Inventors: Jorg Traber, Klaus Opitz
  • Patent number: 4871738
    Abstract: A method of treating warm-blooded animals to reduce their dependency upon nicotine comprising administering to such animals a medicament containing a 2-pyrimidinyl-1-piperazine derivative of the formula ##STR1## in which n stands for 2, 3, 4, 5 or 6 and R stands for ##STR2##
    Type: Grant
    Filed: October 25, 1988
    Date of Patent: October 3, 1989
    Assignee: Troponwerke GmbH & Co. KG
    Inventors: Klaus Opitz, Maria-Luise Weischer, Jorg Traber