Abstract: The present invention relates to a thermodynamically stable modification of the active compound ramatroban of formula (I). The thermodynamically stable form is prepared either by melting of the metastable form and subsequent recrystallization or by seeding a solution of the metastable active compound with a seed crystal of the thermodynamically stable form. The thermodynamically stable active compound can be employed as an asthma agent.

Abstract: Antiviral new peptides of the formula ##STR1## in which R.sup.3 denotes straight-chain or branched alkyl having up to 8 carbon atoms ordenotes aryl having 6 to 10 carbon atoms or tolyl, andR.sup.4 denotes straight-chain or branched alkyl having up to 8 carbon atoms,and physiologically acceptable salts thereof.

Abstract: Antiviral peptides of the formula ##STR1## in which W is an amino protecting group,A,B,D,E and L each independently is a direct bond, or a radical of the formula ##STR2## R.sup.1 and R.sup.2 each independently is cycloakyl or optionally substituted alkyl or alkenyl,Y is --NHR.sup.10, andR.sup.10 is cycloalkyl or optionally substituted alkyl, and their physiologically acceptable salts.The formula includes a 2-amino-2-methylpropionic acid (AiB) residue, which may optionally be protected, as the N-terminal .alpha.-amino acid. The peptides are expected to be useful as medicaments, in particular as antiviral agents in human and veterinary medicine. The peptides are shown to inhibit aspartyl proteases including human immunodeficiency virus (HIV) protease, to have anti-HIV activity and to inhibit the proliferation of HIV in HIV-I infected human lymphocytes. The peptides are expected to be useful in treating patients having HIV related disorders such as ARC and AIDS.