Abstract: Disclosed herein is a method for the production of isopentenyl diphosphate, dimethylallyl diphosphate and/or isoprenoids derived therefrom.

Abstract: Increasing space-time-yield, carbon-conversion-efficiency and carbon substrate flexibility in the production of fine chemicals The inventors of the current invention have found a surprising positive effect of increased cAMP levels and/or manipulating the PTS system on the space-time-yield, carbon-conversion-efficiency and carbon substrate flexibility of fine chemical production of a host organism. This was achieved by de-regulating adenylate cyclase cyaa by deleting the C-terminal regulatory region leading to increased cAMP levels or deleting the Crr protein activity (carbohydrate repression resistance) which regulates the carbohydrate utilization system. Both lead to increased 2-fucosyllactoe and 6-sialyllactose production (human milk oligosaccharides) and increase carbohydrate usage.

Abstract: Process and Device for heat removal from the effective area of a cooling container with the application of dry-ice as cooling agent, where a refrigerant (e.g. FREON) is circulated in a closed pipe system.According to the construction and degree of charge the gravity cooling system (thermosyphon) or evaporation principle with natural circulation is used to take up the heat from interior space and to supply it to dry-ice as heat of sublimation.The systems of heat transfer are arranged in such a way that even for the inclined cooling container, e.g. at the time of aircraft take-off, at least half of the diagonally arranged heat transfer systems in the interior part are fully active to provide sufficient cooling.