Patents by Inventor Klaus Poelstra

Klaus Poelstra has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7348313
    Abstract: A compound includes a carrier molecule wherein the carrier molecule is linked to a further molecule, wherein the further molecule is at least one cyclic peptide in which the cyclic peptide portion thereof contains at least one sequence encoding a cell receptor recognizing peptide (RRP) and with the proviso that the compound is not a naturally occurring receptor agonist or antagonist. Preferably, the RRP is a receptor specific for Hepatic Stellate Cells (HSC) or a receptor that is up-regulated on HSC during disease. The RFP may be chosen from among a PDGF receptor, a collagen type VI receptor, cytokine receptor(s) such as TGB?, INF? and interleukin?. The cyclic portion of the peptide can contain at least one amino acid sequence RGD or KPT.
    Type: Grant
    Filed: December 15, 2004
    Date of Patent: March 25, 2008
    Assignees: Stichting Voor de Technische Wetenschappen, Rijksuniversiteit Groningen
    Inventors: Klaus Poelstra, Eleonora Beljaars, Drik Klaus Fokke Meijer, Detlef Bruno Igor Schuppan