Patents by Inventor Klaus Prezewowsky

Klaus Prezewowsky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 6.beta.,7.beta.;15,16-Dimethylene-1,4-androstadien-3-ones, their preparation and use as medicinal agents
    Patent number: 4291029
    Abstract: Compounds of the formula ##STR1## wherein the 15,16-methylene group is in the .alpha.- or .beta.-position, andE is ##STR2## are useful as diuretics.
    Type: Grant
    Filed: May 29, 1980
    Date of Patent: September 22, 1981
    Assignee: Schering, Aktiengesellschaft
    Inventors: Rudolf Wiechert, Dieter Bittler, Ulrich Kerb, Klaus Prezewowsky, Jorge Casals-Stenzel, Wolfgang Losert
  • 1,3-Dibenzoic acid esters of 17.alpha.-ethynyl-7.alpha.-methyl-1,3,5(10)-estratriene-1,3,17.beta.-tri ol
    Patent number: 4259325
    Abstract: 1,3-Dibenzoic acid esters of 17.alpha.-ethynyl-7.alpha.-methyl-1,3,5(10)-estratriene-1,3,17.beta.-triol possess strong estrogenic and ovulation-inhibiting activities. As compared to the corresponding diacetic acid ester, these dibenzoic acid esters remain stable over 2-7 months even in the desired, low dosage at a thermal load of up to 60.degree. C.
    Type: Grant
    Filed: April 10, 1979
    Date of Patent: March 31, 1981
    Assignee: Schering Aktiengesellschaft (A.G.)
    Inventors: Klaus Prezewowsky, Hermann Steinbeck, Rudolf Wiechert
  • 4-Androsten-3-ones and process for the preparation thereof
    Patent number: 4118488
    Abstract: 4-Androsten-3-ones of the formula ##STR1## wherein R.sub.1 is hydrogen or the acyl radical of an organic or inorganic acid, R.sub.2 is hydrogen, alkyl, or the acyl radical of an organic or inorganic acid, R.sub.3 is methyl or ethyl, R.sub.4 is hydrogen or methyl, ##STR2## and R.sub.5 is lower alkyl, have diuretic activity.
    Type: Grant
    Filed: March 3, 1977
    Date of Patent: October 3, 1978
    Assignee: Schering Aktiengesellschaft
    Inventors: Rainer Philippson, Bernhard Krieger, Jorge Casals-Stenzel, Ulrich Kerb, Wolfgang Losert, Klaus Prezewowsky, Rudolf Wiechert, Dieter Bittler
  • 7-Hydroxyestradiols
    Patent number: 4011314
    Abstract: 7-Hydroxyestradiols of the formula ##STR1## wherein R.sub.1 is hydrogen, acyl, alkyl, cycloalkyl, an oxygenated saturated heterocyclic group or hydrocarbylsulfonyl; R.sub.2 and R.sub.3 each are hydrogen, acyl, oxygenated saturated heterocyclic group or R.sub.2 is hydrocarbylsulfonyl and R.sub.4 is alkyl, alkenyl, chlorinated alkenyl, alkynyl or chlorinated alkynyl, are useful for treating estrogen deficiency symptoms.
    Type: Grant
    Filed: October 9, 1975
    Date of Patent: March 8, 1977
    Assignee: Schering Aktiengesellschaft
    Inventors: Karl Petzoldt, Hans-Jorg Vidic, Klaus Prezewowsky, Yukishige Nishino, Rudolf Wiechert, Henry Laurent
  • 3,17,18-Trihydroxy-1,3,5(10)-estratrienes
    Patent number: 3960841
    Abstract: 3,17,18-Trihydroxy-1,3,5(10)-estratrienes of the formula ##SPC1##Wherein R is H or substituted or unsubstituted saturated or unsaturated hydrocarbon, and esters and ethers thereof, possess strong vaginotropic and only weak utertropic activity and are useful in the treatment of estrogenic deficiency conditions where uteral effects are not desired.
    Type: Grant
    Filed: July 12, 1974
    Date of Patent: June 1, 1976
    Assignee: Schering Aktiengesellschaft
    Inventors: Klaus Engel, Klaus Prezewowsky, Henry Laurent, Yukishige Nishino
  • 1,3-Oxygenated-8.alpha.-estratrienes
    Patent number: 3951958
    Abstract: 1,3-Dihydroxy-8.alpha.-estratrienes of the formula ##SPC1##Wherein R is lower-alkyl and --A--B is ##SPC2##Wherein R' is a saturated or unsaturated hydrocarbon group and R" is lower-alkyl, aralkyl or phenyl, and the esters and ethers thereof, possess strong vaginotropic but only weak utertropic activity and are useful in the treatment of estrogenic deficiency conditions where uteral effects are not desired.
    Type: Grant
    Filed: July 12, 1974
    Date of Patent: April 20, 1976
    Assignee: Schering Aktiengesellschaft
    Inventors: Klaus Prezewowsky, Henry Laurent, Helmut Hofmeister, Rudolf Wiechert, Friedmund Neumann, Yukishige Nishino
  • 1,3-Oxygenated 8.alpha.-estratrienes
    Patent number: 3951959
    Abstract: 8.alpha.-Estratrienes of the formula ##SPC1##Wherein R is lower alkyl and X is an oxygen atom, a .beta.-hydroxy or .beta.-hydroxy-.alpha.-substituted or unsubstituted saturated or unsaturated hydrocarbon group, and the esters and ethers thereof, possess strong vaginotropic but only weak utertropic activity and are useful in the treatment of estrogenic deficiency conditions where uteral effects are not desired.
    Type: Grant
    Filed: July 12, 1974
    Date of Patent: April 20, 1976
    Assignee: Schering Aktiengesellschaft
    Inventors: Klaus Prezewowsky, Henry Laurent, Helmut Hofmeister, Rudolf Wiechert, Friedmund Neumann, Yukishige Nishino