Patents by Inventor Klaus Sandrock

Klaus Sandrock has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical compositions containing 1-oleylazacycloheptan-2-one as enhancing agent of transport across biological membranes
    Patent number: 6284754
    Abstract: The invention relates to pharmaceutical compositions for topical application containing at least one physiologically active agent and an effective amount of 1-oleylazacycloheptan-2-one as the human or animal epithelial membrane permeability enhancer, to the application of such pharmaceutical compositions by means of locally contacting the skin or other membrane of the human or animal with the above composition and to the 1-oleylazacycloheptan-2-one compound per se.
    Type: Grant
    Filed: January 14, 1993
    Date of Patent: September 4, 2001
    Assignee: Schwarz Pharma AG
    Inventors: Henri Ernest Boddé, Johanna Aaltje Bouwstra, Maria Helène Ponec, Ferdinand Spies, Klaus Sandrock, Johannes Brussee
  • Organic nitrates containing a disulfide group as cardiovascular agents
    Patent number: 5661129
    Abstract: The invention relates to novel nitrates containing a disulphide group, and to processes for their preparation. The compounds can be used for the therapy of disorders of the cardiovascular system.
    Type: Grant
    Filed: December 5, 1995
    Date of Patent: August 26, 1997
    Assignee: Schwarz Pharma AG
    Inventors: Martin Feelisch, Hilmar Bokens, Jochen Lehmann, Claus Meese, Klaus Sandrock
  • Organic nitrates and method for their preparation
    Patent number: 5428061
    Abstract: New organic nitrate compounds, formed by condensing a nitrato alkanoic acid with a sulfur-containing amino acid or peptide, which prevent nitrate tolerance or overcome existing tolerance and which are useful for the treatment of cardiac diseases including circulatory diseases, high blood pressure, cardiac insufficiency and for dilating the peripheral vessels.
    Type: Grant
    Filed: September 7, 1993
    Date of Patent: June 27, 1995
    Assignee: Schwarz Pharma AG
    Inventors: Klaus Sandrock, Joachim Hutter, Eike Noack
  • Nitrato alkanoic acid derivatives, methods for their production, pharmaceutical compositions containing the derivatives and medicinal uses thereof
    Patent number: 5284872
    Abstract: New organic nitrate compounds, formed by condensing a nitrato alkanoic acid with a sulfur-containing amino acid or peptide followed by the reaction of the resulting product with an amino acid, N-acylamino acid, peptide or an N-acyl peptide to produce a thio ester thereof, which prevent nitrate tolerance or overcome existing tolerance and which are useful for the treatment of cardiac diseases including circulatory diseases, coronary dilation, high blood pressure, cardiac insufficiency and for dilating the peripheral vessels.
    Type: Grant
    Filed: April 5, 1991
    Date of Patent: February 8, 1994
    Assignee: Schwarz Pharma AG
    Inventors: Klaus Sandrock, Eike Noack, Edgar Fritschi, Ralf Kanzler, Martin Feelisch
  • Process for selectively producing isosorbide-5-nitrate
    Patent number: 4297286
    Abstract: The present invention is related to a new process for selectively preparing isosorbide-5-nitrate (1.4-3.6-dianhydrosorbitol-5-nitrate) by subjecting isomannide (1.4-3.
    Type: Grant
    Filed: January 24, 1980
    Date of Patent: October 27, 1981
    Assignee: Sanol Schwarz-Monhein GmbH
    Inventors: Klaus Sandrock, Gunter Cordes