Patents by Inventor Klaus Schaefer

Klaus Schaefer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11452786
    Abstract: The present invention relates to a compound or a pharmaceutically acceptable salt thereof having a chemical structure comprising: A compound or a pharmaceutically acceptable salt thereof of formula (I): (A)-x1-(B)-x2-(C), wherein (A) is at least one motif specifically binding to cell membranes of neoplastic cells; (B) at least one chelator moiety of radiometals; (C) a dye moiety; x1 is a spacer covalently connecting (A) and (B); x2 is a spacer or a chemical single bond connecting (B) and (C); wherein (C) has the formula wherein R1 to R4, R9, a, b, Y and X1 to X4 have the meaning as indicated in the claims and description. The invention further relates to compositions comprising said compounds as well as a method for detecting neoplastic cells in a sample in vitro with the aid of the compounds or composition.
    Type: Grant
    Filed: November 12, 2018
    Date of Patent: September 27, 2022
    Assignees: Deutsches Krebsforschungszentrum, Ruprecht-Karls-Universitaet Heidelberg
    Inventors: Ann-Christin Eder, Matthias Eder, Klaus Kopka, Martin Schaefer, Ulrike Bauder-Wuest, Uwe Haberkorn
  • Patent number: 11284566
    Abstract: A combine harvester for carrying out an agricultural harvesting process has a plurality of working units and a driver assistance system for controlling at least some of the working units. The combine harvester accommodates as working units a chaff cutter for comminuting harvested produce and a produce distributing arrangement in the rear area of the combine harvester downstream of the chaff cutter for distributing harvested produce on the field soil in adjustable throw directions. The respective throw direction comprises vector components of a horizontal throw direction and a vertical throw direction. The driver assistance system is adapted to optimize the control of the produce distributing arrangement by at least one of the substrategies including “throw direction correction” and/or “inclination-dependent produce distribution” and/or “produce distribution in longitudinal direction” and/or “produce distribution in transverse direction” with respect to at least one optimization criterion.
    Type: Grant
    Filed: July 23, 2019
    Date of Patent: March 29, 2022
    Assignee: CLAAS Selbstfahrende Erntemaschinen GmbH
    Inventors: Joachim Baumgarten, Bastian Bormann, Andreas Wilken, Christopher Vieregge, Stefan Teroerde, Christoph Heitmann, Klaus Schaefer
  • Publication number: 20210402651
    Abstract: Techniques recycle plastics in multiple successive process steps. A polymer, preferably a recyclable material, is melted using a discharge extruder, filtered using a first filter device under a positive pressure atmosphere, filtered and degassed using a degassing device, and discharged using a discharge extruder. The degassing device has at least one filter element and a vacuum chamber with a negative pressure atmosphere for filtering and degassing purposes, wherein the plastic melt can be conducted into the negative pressure atmosphere of the vacuum chamber through the filter element.
    Type: Application
    Filed: November 19, 2019
    Publication date: December 30, 2021
    Inventor: Klaus Schäfer
  • Patent number: 11081923
    Abstract: The present disclosure relates to electrical machines. The teachings thereof may be embodied in a corona shielding system for an electrical machine. For example, a corona shielding system may include: an outer corona shield and an overhang corona shielding. The outer corona shielding and the overhang corona shielding may comprise a first corona shielding material having a nonlinear field strength-dependent electrical resistance.
    Type: Grant
    Filed: August 3, 2015
    Date of Patent: August 3, 2021
    Assignee: SIEMENS AKTIENGESELLSCHAFT
    Inventors: Bernhard Klaussner, Jiri Lang, Steffen Lang, Alexander Litinsky, Guido Schmidt, Christian Schulz-Drost, Klaus Schaefer, Christian Staubach
  • Patent number: 10862362
    Abstract: The present disclosure relates to electrical machines. The teachings thereof may be embodied in a corona shielding system, especially for an electrical machine, e.g., a high-voltage machine, such as a generator for generation of electrical energy, an electric motor, or another piece of electrical equipment having a relatively high rated voltage, e.g., a transformer or a bushing or a cable. A corona shielding system may include: a polymeric matrix; and filler particles comprising mica surrounded by a layer of at least one ceramic metal oxide. The filler particles may be distributed throughout the polymeric matrix.
    Type: Grant
    Filed: August 3, 2015
    Date of Patent: December 8, 2020
    Assignee: SIEMENS AKTIENGESELLSCHAFT
    Inventors: Bernhard Klaussner, Jiri Lang, Steffen Lang, Alexander Litinsky, Guido Schmidt, Christian Schulz-Drost, Klaus Schaefer, Christian Staubach
  • Publication number: 20200354495
    Abstract: A mixture includes at least two radically curable compounds as a backbone resin, and is useful in reactive resins. In particular, the mixture reduces the viscosity of such reactive resin-containing mixtures and thus the dispensing forces required for ejecting the reactive resin components produced therefrom. The mixture also increases the performance of the reactive resins containing such mixtures and of the reactive resin components produced therefrom. Further, said reactive resins and the reactive resin components thereof are useful for construction purposes, in particular for chemical fastening.
    Type: Application
    Filed: July 24, 2020
    Publication date: November 12, 2020
    Applicant: Hilti Aktiengesellschaft
    Inventors: Georg NICKERL, Jens Bunzen, Beate Gnass, Gerald Gaefke, Thomas Bürgel, Klaus Schaefers
  • Patent number: 10829578
    Abstract: A mixture includes at least two radically curable compounds as a backbone resin, and is useful in reactive resins. In particular, the mixture reduces the viscosity of such reactive resin-containing mixtures and thus the dispensing forces required for ejecting the reactive resin components produced therefrom. The mixture also increases the performance of the reactive resins containing such mixtures and of the reactive resin components produced therefrom. Further, said reactive resins and the reactive resin components thereof are useful for construction purposes, in particular for chemical fastening.
    Type: Grant
    Filed: June 20, 2018
    Date of Patent: November 10, 2020
    Assignee: Hilti Aktiengesellschaft
    Inventors: Georg Nickerl, Jens Bunzen, Beate Gnass, Gerald Gaefke, Thomas Bürgel, Klaus Schaefers
  • Patent number: 10736249
    Abstract: A corona shielding paper for use in a corona shielding system for an electric machine, e.g. a high-voltage machine, may be produced by compacting partial discharge-resistant, planar, conductive particles but can include both reinforcement fibers and a woven fabric.
    Type: Grant
    Filed: February 26, 2015
    Date of Patent: August 4, 2020
    Assignee: SIEMENS AKTIENGESELLSCHAFT
    Inventors: Florian Eder, Bernhard Klaussner, Jiri Lang, Steffen Lang, Alexander Litinsky, Guido Schmidt, Christian Schulz-Drost, Klaus Schaefer, Christian Staubach
  • Publication number: 20200198210
    Abstract: Techniques involve cleaning a polymer melt, which allow volatile foreign substances and solid foreign substances to be removed from the polymer melt. Such techniques involve a filter element and a vacuum of a vacuum chamber. The polymer melt is fed through the filter element into the vacuum of the vacuum chamber, The filter element binds the solid foreign substances and the vacuum chamber takes up the volatile foreign substances.
    Type: Application
    Filed: September 3, 2018
    Publication date: June 25, 2020
    Inventors: Klaus Schäfer, Jörg Alexander, Friedel Dickmeiss, Matthias Schmitz
  • Patent number: 10673294
    Abstract: The present disclosure relates to electrical machines. The teachings thereof may be embodied in a corona shielding system, especially an outer corona shielding system, for an electrical machine. For example, a corona shielding system may include: a polymeric matrix; particles disposed in the matrix, including a mica-coated core and a layer of metal oxide disposed on the core; and a surface functionalization material disposed on a surface of the particles for binding to the matrix.
    Type: Grant
    Filed: August 3, 2015
    Date of Patent: June 2, 2020
    Assignee: SIEMENS AKTIENGESELLSCHAFT
    Inventors: Bernhard Klaussner, Jiri Lang, Steffen Lang, Alexander Litinsky, Guido Schmidt, Christian Schulz-Drost, Klaus Schaefer, Christian Staubach
  • Publication number: 20200140593
    Abstract: A mixture includes at least two radically curable compounds as a backbone resin, and is useful in reactive resins. In particular, the mixture reduces the viscosity of such reactive resin-containing mixtures and thus the dispensing forces required for ejecting the reactive resin components produced therefrom. The mixture also increases the performance of the reactive resins containing such mixtures and of the reactive resin components produced therefrom. Further, said reactive resins and the reactive resin components thereof are useful for construction purposes, in particular for chemical fastening.
    Type: Application
    Filed: June 20, 2018
    Publication date: May 7, 2020
    Applicant: Hilti Aktiengesellschaft
    Inventors: Georg Nickerl, Jens Bunzen, Beate Gnass, Gerald Gaefke, Thomas Bürgel, Klaus Schaefers
  • Publication number: 20200095367
    Abstract: Low-viscosity urethane methacrylate compounds are used as a backbone resin in reactive resins. In particular, the compounds are for lowering the viscosity of reactive resins containing such mixtures and thus the extrusion forces of reactive resin components produced therefrom and also for increasing the performance of reactive resins and reactive resin components produced therefrom containing such compounds. Furthermore, said compounds and their reactive resin components are used for construction purposes, in particular for chemical fastening.
    Type: Application
    Filed: June 19, 2018
    Publication date: March 26, 2020
    Applicant: Hilti Aktiengesellschaft
    Inventors: Georg Nickerl, Beate Gnass, Natja Park, Jens Bunzen, Klaus Schaefers, Ralf Neuerburg, Rainer Strobel-Schmidt, Gerald Gaefke
  • Publication number: 20200060092
    Abstract: A combine harvester for carrying out an agricultural harvesting process has a plurality of working units and a driver assistance system for controlling at least some of the working units. The combine harvester accommodates as working units a chaff cutter for comminuting harvested produce and a produce distributing arrangement in the rear area of the combine harvester downstream of the chaff cutter for distributing harvested produce on the field soil in adjustable throw directions. The respective throw direction comprises vector components of a horizontal throw direction and a vertical throw direction. The driver assistance system is adapted to optimize the control of the produce distributing arrangement by at least one of the substrategies including “throw direction correction” and/or “inclination-dependent produce distribution” and/or “produce distribution in longitudinal direction” and/or “produce distribution in transverse direction” with respect to at least one optimization criterion.
    Type: Application
    Filed: July 23, 2019
    Publication date: February 27, 2020
    Applicant: CLAAS Selbstfahrende Erntemaschinen GmbH
    Inventors: Joachim Baumgarten, Bastian Bormann, Andreas Wilken, Christopher Vieregge, Stefan Teroerde, Christoph Heitmann, Klaus Schaefer
  • Patent number: 10506748
    Abstract: A corona shielding system for an electric machine, for example a high-voltage machine, such as a generator, for generating electrical energy, an electric motor or else other electric operating means having a relatively high rated voltage, such as transformers, bushings, cables, etc, is disclosed. The corona shielding system may include a filler mixture including both planar and spherical particles. Therefore, the electrical conductivity, which is good in the presence of only planar particles in two spatial directions but is very poor in the third, can be adjusted anisotropically in a targeted manner.
    Type: Grant
    Filed: February 25, 2015
    Date of Patent: December 10, 2019
    Assignee: SIEMENS AKTIENGESELLSCHAFT
    Inventors: Bernhard Klaussner, Jiri Lang, Steffen Lang, Alexander Litinsky, Guido Schmidt, Christian Schulz-Drost, Klaus Schaefer, Christian Staubach
  • Patent number: 10126929
    Abstract: An agricultural work machine for processing an agricultural work process, having numerous working units (1-5) and having a driver assistance system (10) for controlling the working units (1-5) according to at least one user-side specifiable work process strategy (A), which is aimed at fulfilling at least one quality criterion (Q), wherein the driver assistance system (10) comprises a memory (11) for storing data, and a computing device (12) for processing the data stored in the memory (11), wherein the driver assistance system (10) has a graphical user interface (14), via which at least a portion of the work process strategy (A) can be specified by a user. It is proposed that competing quality criteria (Q) that are weighted in relation to one another in accordance with a weighting variable (G) are entered into the work process strategy (A), and that the weighting variable (G) is visualized and can be specified by a user via a virtual operating element (16-19) of the graphical user interface (14).
    Type: Grant
    Filed: November 17, 2016
    Date of Patent: November 13, 2018
    Assignee: CLAAS Selbstfahrende Erntemaschinen GmbH
    Inventors: Joachim Baumgarten, Andreas Wilken, Christoph Heitmann, Bastian Bormann, Sebastian Neu, Christoph Bussmann, Klaus Schäfer, Henner Vöcking, Arthur Berger, Stefan Terörde
  • Patent number: 9808203
    Abstract: A method includes introducing the examination object into an examination region of a combination device; recording emission computed tomography data over a measurement period and storing detection events and detection instants associated therewith; measuring magnetic resonance data of at least two subregions of the examination region at at least two instants during the recording period of the emission computed tomography data and storing the magnetic resonance data and the recording instants; determining motion information describing a motion of a region of the examination object at a first instant relative to the position at a second instant from the magnetic resonance data recorded at the first instant and the second instant, for each subregion; determining a motion model describing motion of the examination object, for the entire object, from information for the subregions; and calculating motion-corrected emission tomography data from detection events, detection instants and the motion model.
    Type: Grant
    Filed: May 20, 2014
    Date of Patent: November 7, 2017
    Assignees: Siemens Aktiengesellschaft, Westfaelische Wilhems-Universitaet Muenster
    Inventors: Carmel Hayes, Ralf Ladebeck, Klaus Schäfers
  • Publication number: 20170294817
    Abstract: The present disclosure relates to electrical machines. The teachings thereof may be embodied in a corona shielding system for an electrical machine. For example, a corona shielding system may include: an outer corona shield and an overhang corona shielding. The outer corona shielding and the overhang corona shielding may comprise a first corona shielding material having a nonlinear field strength-dependent electrical resistance.
    Type: Application
    Filed: August 3, 2015
    Publication date: October 12, 2017
    Applicant: Siemens Aktiengesellschaft
    Inventors: Bernhard Klaussner, Jiri Lang, Steffen Lang, Alexander Litinsky, Guido Schmidt, Christian Schulz-Drost, Klaus Schaefer, Christian Staubach
  • Publication number: 20170288488
    Abstract: The present disclosure relates to electrical machines. The teachings thereof may be embodied in a corona shielding system, especially an outer corona shielding system, for an electrical machine. For example, a corona shielding system may include: a polymeric matrix; particles disposed in the matrix, including a mica-coated core and a layer of metal oxide disposed on the core; and a surface functionalization material disposed on a surface of the particles for binding to the matrix.
    Type: Application
    Filed: August 3, 2015
    Publication date: October 5, 2017
    Applicant: Siemens Aktiengesellschaft
    Inventors: Bernhard Klaussner, Jiri Lang, Steffen Lang, Alexander Litinsky, Guido Schmidt, Christian Schulz-Drost, Klaus Schaefer, Christian Staubach
  • Publication number: 20170288487
    Abstract: The present disclosure relates to electrical machines. The teachings thereof may be embodied in a corona shielding system, especially for an electrical machine, e.g., a high-voltage machine, such as a generator for generation of electrical energy, an electric motor, or another piece of electrical equipment having a relatively high rated voltage, e.g., a transformer or a bushing or a cable. A corona shielding system may include: a polymeric matrix; and filler particles comprising mica surrounded by a layer of at least one ceramic metal oxide. The filler particles may be distributed throughout the polymeric matrix.
    Type: Application
    Filed: August 3, 2015
    Publication date: October 5, 2017
    Applicant: Siemens Aktiengesellschaft
    Inventors: Bernhard Klaussner, Jiri Lang, Steffen Lang, Alexander Litinsky, Guido Schmidt, Christian Schulz-Drost, Klaus Schaefer, Christian Staubach
  • Patent number: 9725277
    Abstract: A take-up winding machine continuously coils a plurality of threads. The take-up winding machine has a plurality of rotatably mounted winding turrets which, in each case, support two protruding winding spindles and which are held beside one another in a machine frame so as to be spaced apart by a pitch. The take-up winding machine further has a plurality of traversing units and a plurality of contact rollers which together with the winding turrets form a plurality of coiling positions. The winding turrets are assigned one common turret drive. The winding turrets are configured so as to be drivable in the same direction. The contact rollers and the traversing units are held on the machine frame along one machine longitudinal side so as to be symmetrical to the pitch of the winding turrets.
    Type: Grant
    Filed: January 8, 2014
    Date of Patent: August 8, 2017
    Assignee: Oerlikon Textile GmbH & Co. KG
    Inventors: Michael Schröter, Friedrich Lennemann, Klaus Schäfer