Patents by Inventor Klaus Schultes

Klaus Schultes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20060052515
    Abstract: The present invention relates to a process for preparing an aqueous dispersion, by a) forming an initial charge from water and emulsifier, b) adding from 25.0 to 45.0 parts by weight of a first composition comprising A) from 50.0 to 99.9 parts by weight of alkyl methacrylates, B) from 0.0 to 40.0 parts by weight of alkyl acrylates, C) from 0.1 to 10.0 parts by weight of crosslinking monomers and D) from 0.0 to 8.0 parts by weight of styrenic monomers and polymerizing, c) adding from 35.0 to 55.0 parts by weight of a second composition comprising E) from 80.0 to 100.0 parts by weight of (meth) acrylates F) from 0.05 to 10.0 parts by weight of crosslinking monomers and G) from 0.0 to 20.0 parts by weight of styrenic monomers, and polymerizing, d) adding from 10.0 to 30.0 parts by weight of a third composition comprising H) from 50.0 to 100.0 parts by weight of alkyl methacrylates, I) from 0.0 to 40.0 parts by weight of alkyl acrylates and J) from 0.0 to 10.
    Type: Application
    Filed: October 18, 2003
    Publication date: March 9, 2006
    Applicant: Roehm Gmbh & Co. KG
    Inventors: Klaus Schultes, Thomas Suefke, Reiner Mueller, Hartmut Schikowsky, Werner Hoess
  • Patent number: 6998140
    Abstract: The invention relates to a dispersion suitable for use as coating agent and binder for pharmaceutical forms, having a solids content of 10–70% by weight consisting of a) from 90 to 99% by weight of a methacrylate copolymer consisting of at least 90% by weight of (meth)acrylate monomers containing neutral radicals and having a glass transition temperature Tg of from ?20° C. to +20° C. as determined by the DSC method, and b) 1–10% by weight of a nonionic emulsifier having an HLB of from 15.2 to 17.3.
    Type: Grant
    Filed: February 2, 2001
    Date of Patent: February 14, 2006
    Assignee: Roehm GmbH & Co. KG
    Inventors: Christian Meier, Johanna Eisele, Michael Schnabel, Klaus Schultes, Stefan Grimm, Hans-Ulrich Petereit, Thomas Suefke
  • Publication number: 20050154165
    Abstract: The invention relates to a pH-sensitive polymer which is a (meth)acrylate copolymer composed of 20 to 65% by weight acrylic and/or methacrylic acid units and 80 to 35% by weight units of C1- to C18-alkyl esters of (meth)acrylic acid, characterized in that it has a molecular weight in the range from 1 000 to 50 000 g/mol, and brings about at least 60% haemolysis at pH 5.5, and less than 5% haemolysis at pH 7.4, in a concentration of 150 ?g/ml in a cytotoxicity test with human red blood cells. The invention further relates to the use of the pH-sensitive polymer as carrier for pharmaceutically effective biomolecules or active pharmaceutical ingredients and as ingredient of corresponding dosage forms.
    Type: Application
    Filed: October 22, 2002
    Publication date: July 14, 2005
    Inventors: Hans-Ulrich Petereit, Christian Meier, Klaus Schultes, Marie Yessine, Jean-Christophe Leroux
  • Publication number: 20050152977
    Abstract: The invention relates to a process for producing a coated drug form or a drug form in the form of an active ingredient matrix, by processing a copolymer, an active pharmaceutical ingredient, a core if present and/or pharmaceutically customary excipients in a conventional manner by melting, injection molding, extrusion, wet granulation, casting, dipping, spreading, spraying or compression to form a coated drug form and/or to form an active ingredient matrix, characterized in that a copolymer is used which is composed of 20 to 33% by weight methacrylic acid, 5 to 30% by weight methyl acrylate, 20 to 40% by weight ethyl acrylate and more than 10 to 30% by weight butyl methacrylate and, if desired, 0 to 10% by weight further vinylically copolymerizable monomers, with the proviso that the glass transition temperature of the copolymer in accordance with ISO 11357-2, section 3.3.3, is 55 to 70° C.
    Type: Application
    Filed: March 2, 2004
    Publication date: July 14, 2005
    Inventors: Hans-Ulrich Petereit, Christian Meier, Klaus Schultes
  • Patent number: 6906142
    Abstract: The invention relates to an impact-modified moulding composition which has particularly high impact resistance at low temperatures (?20° C., ?40° C.). This low-temperature impact resistance is achieved by using a silicone elastomer.
    Type: Grant
    Filed: October 22, 2001
    Date of Patent: June 14, 2005
    Assignee: Roehm GmbH & Co. KG
    Inventors: Klaus Schultes, Michael Wicker, Werner Hoess, Klaus Albrecht, Hans-Juergen Kress
  • Publication number: 20050124761
    Abstract: The invention relates to core-shell structured silicone rubber graft polymers that comprise a core a) from a silicium-organic polymer that corresponds to the general formula (R2SiO2/2)x.(RSiO3/2)y.(SiO4/2)z, wherein x=0 to 99.5 mole %, y=0.5 to 100 mole %, z=0 to 50 mole %, wherein R is the same or different and represents alkyl or alkenyl groups having 1 to 6 C atoms, aryl groups or substituted hydrocarbon groups and at last one shell c) from an organic polymer. The silicone rubber graft copolymers are obtained by producing the organic shell c) by radical polymerization at a temperature of not more than 65° C. and adding the initiator in at least two portions to the reaction vessel, with a further addition at least 2 minutes after start of the polymerization.
    Type: Application
    Filed: January 14, 2003
    Publication date: June 9, 2005
    Inventors: Klaus Schultes, Reiner Mueller, Werner Hoess, Klaus Albrecht
  • Patent number: 6890993
    Abstract: The invention relates to an impact-modified molding composition which has particularly high impact resistance at low temperatures (?20° C., ?40° C.). This low-temperature impact resistance is achieved by using a silicone elastomer.
    Type: Grant
    Filed: October 22, 2001
    Date of Patent: May 10, 2005
    Assignee: Roehm GmbH & Co. KG
    Inventors: Klaus Schultes, Michael Wicker, Werner Hoess, Klaus Albrecht, Hans-Juergen Kress
  • Publication number: 20050080188
    Abstract: The invention relates to impact-resistant moulding materials comprising poly(meth)acrylate and at least one silicon rubber graft polymer comprising between 0.05 and 95 wt. %, in relation to the total weight of the copolymer, of a core a) consisting of an organosilicon polymer of general formula (R2SiO2/2)x (RSiO3/2)Y (SiO4/2)x wherein x=between 0 and 99.5 mole %, y=between 0.5 and 100 mole %, z=between 0 and 50 mole %, and R represents alkyl or alkenyl radicals comprising between 1 and 6 C atoms and being the same or different, aryl radicals or substituted hydrocarbon radicals; between 0 and 94.5 wt. %, in relation to the total weight of the copolymer, of a polydialkylsiloxane layer b); between 5 and 95 wt. %, in relation to the total weight of the copolymer, of an envelope c) consisting of organic polymers. The invention is characterised in that the core a) comprises vinyl groups, and the envelope c) can be obtained by radical polymerisation of a mixture containing acrylic acid esters and methacrylates.
    Type: Application
    Filed: January 14, 2003
    Publication date: April 14, 2005
    Applicant: ROEHM GBMH & CO KG
    Inventors: Klaus Schultes, Reiner Mueller, Werner Hoess, Klaus Albrecht
  • Publication number: 20050065224
    Abstract: The invention relates to a macroporous plastics bead material with an average particle diameter from 10 to 1000 ?m, containing a copolymer of a) 5-60 wt. % vinylically polymerizable monomers with a water solubility of at least 1% at 20° C., b) 1-40 wt. % vinylically polymerizable monomers with an additional functional group, which can enter into covalent bonds with the nucleophilic groups of the ligands in a polymer-like reaction, c) 10-40 wt. % hydrophilic, crosslinking radical-polymerizable monomers with two or more ethylenically unsaturated polymerizable groups and d) 10-60 wt. % vinylically polymerizable monomers with a water solubility of at most 1% at 20° C. are contained, as a rule with the monomers a) to d) adding up to 100%.
    Type: Application
    Filed: August 25, 2003
    Publication date: March 24, 2005
    Inventors: Stefan Menzler, Hans-Ulrich Petereit, Christian Meier, Thomas Boller, Thomas Suefke, Klaus Schultes, Roger Recktenwald
  • Patent number: 6809163
    Abstract: The present invention provides a process for preparing bead polymers having an average particle size of 1 to 40 &mgr;m, which includes: contacting: at least one polymerizable mix which includes at least 50% by weight of at least one (meth)acrylate monomer, at least one aluminum compound, and an aqueous phase, to prepare a mixture; dispersing the mixture at a shear rate≧103 s−1 to form a dispersion, wherein the dispersion is stabilized by the aluminum compound; and polymerizing to produce bead polymers having an average particle size of 1 to 40 &mgr;m.
    Type: Grant
    Filed: December 28, 2001
    Date of Patent: October 26, 2004
    Assignee: Roehm GmbH & Co KG
    Inventors: Klaus Schultes, Thomas Suefke, Markus Parusel, Guenter Schmitt, Winfried Belzner
  • Patent number: 6803416
    Abstract: The present invention provides a moulding composition, which includes: a plurality of bead polymers dispersed in at least one matrix polymer; wherein the bead polymers: have an average particle size of 5 to 40 &mgr;m, and have a refractive index nD at 20° C. which is different from a refractive index nD at 20° C. of said matrix polymer; and wherein the bead polymers are prepared by a process, which includes: contacting: at least one polymerizable mix which includes at least 50% by weight of at least one (meth)acrylate monomer, at least one aluminum compound, and an aqueous phase, to prepare a mixture; dispersing the mixture at a shear rate ≧103 s−1 to form a dispersion, wherein the dispersion is stabilized by the aluminum compound; and polymerizing to produce the bead polymers having an average particle size of 5 to 40 &mgr;m.
    Type: Grant
    Filed: December 28, 2001
    Date of Patent: October 12, 2004
    Assignee: Roehm GmbH & Co. KG
    Inventors: Klaus Schultes, Thomas Suefke, Markus Parusel, Werner Hoess
  • Publication number: 20040116567
    Abstract: The invention relates to a hot sealing system comprised of an olefin polymer or of an olefin polymer A, of a methacrylate polymer B, of a graft polymer A-X consisting of the above-mentioned constituents and of a solvent or solvent mixture. The hot sealing system is characterized by having a high thermal stability and short sealing times.
    Type: Application
    Filed: January 6, 2004
    Publication date: June 17, 2004
    Inventors: Gunter Schmitt, Michael Wicke, Juergen Hartmann, Klaus Schultes, Helmut Schwind, Thomas Arnold
  • Publication number: 20040030046
    Abstract: The invention relates to a novel impact-resistance modifier, constructed from a core-shell 1 and a shell 2, whereby the core is plastically deformable. The invention is characterised by excellent mechanical properties obtained by a low content of impact-resistance modifier.
    Type: Application
    Filed: August 18, 2003
    Publication date: February 12, 2004
    Inventors: Klaus Schultes, Thomas Suefke, Reiner Mueller, Thomas Arndt, Goerg Michler, Joachim Laatsch
  • Publication number: 20040024121
    Abstract: The invention relates to an impact-modified moulding composition which has particularly high impact resistance at low temperatures (−20° C., −40° C.). This low-temperature impact resistance is achieved by using a silicone elastomer.
    Type: Application
    Filed: April 30, 2003
    Publication date: February 5, 2004
    Inventors: Klaus Schultes, Michael Wicker, Werner Hoess, Klaus Albrecht, Hans-Juergen Kress
  • Publication number: 20030060381
    Abstract: The invention relates to a dispersion suitable for use as coating agent and binder for pharmaceutical forms, having a solids content of 10-70% by weight consisting of
    Type: Application
    Filed: November 9, 2001
    Publication date: March 27, 2003
    Inventors: Christian Meier, Johanna Eisele, Michael Schnabel, Klaus Schultes, Stefan Grimm, Hans-Ulrich Petereit, Thomas Suefke
  • Publication number: 20020123565
    Abstract: The present invention provides a moulding composition, which includes:
    Type: Application
    Filed: December 28, 2001
    Publication date: September 5, 2002
    Applicant: ROEHM GMBH & CO. KG
    Inventors: Klaus Schultes, Thomas Suefke, Markus Parusel, Werner Hoess
  • Publication number: 20020123563
    Abstract: The present invention provides a process for preparing bead polymers having an average particle size of 1 to 40 &mgr;m, which includes:
    Type: Application
    Filed: December 28, 2001
    Publication date: September 5, 2002
    Applicant: ROEHM GMBH & CO. KG
    Inventors: Klaus Schultes, Thomas Suefke, Markus Parusel, Guenter Schmitt, Winfried Belzner
  • Patent number: 6355712
    Abstract: The present invention is directed to a copolymer containing a hydrophilic copolymerizable monomer and a plastisol obtained by the use of the copolymer, which exhibits reduced viscosity and longer pot-life.
    Type: Grant
    Filed: March 28, 2000
    Date of Patent: March 12, 2002
    Assignee: Roehm GmbH & Co KG
    Inventors: Klaus Schultes, Guenther Schmitt, Andreas Olschewski, Theodor Mager
  • Patent number: 6353053
    Abstract: The present invention is directed to a process and corresponding device for incorporating expanded graphite in a gentle manner into a polyurethane reactive mixture and, on the other hand, processes and corresponding means for reducing or preventing sedimentation of the expanded graphite in the liquid.
    Type: Grant
    Filed: August 13, 1999
    Date of Patent: March 5, 2002
    Assignee: Bayer Aktiengesellschaft
    Inventors: Wolfgang Friedrichs, Uwe Künzel, Kurt Krippl, Klaus Schulte
  • Patent number: 6297342
    Abstract: The present invention is directed to an agitator-free mixing head and a method for agitator-free production of a reaction mixture from an isocyanate and a higher-viscous polyol formulation, wherein both constituents are fed to a mixing zone and mixed with each other therein, whereby a polyol formulation with a viscosity of at least 3000 mPa.s is fed at low pressure into the mixing zone and at least two flows of low-viscosity constituents (isocyanate and optionally low-viscous polyol) are injected into the flow of high-viscous polyol formulation at high pressure.
    Type: Grant
    Filed: August 13, 1999
    Date of Patent: October 2, 2001
    Assignee: Bayer Aktiengesellschaft
    Inventors: Klaus Schulte, Kurt Krippl, Wolfgang Friederichs, Uwe Künzel, Hans-Ulrich Weber