Abstract: A composition for coloring keratin fibers, containing an indoline, an indole, or a derivative thereof in combination with at least one amino acid or oligopeptide. The composition is useful for coloring human hair and restoring grey hair to its natural color. The formulation can be applied with atmospheric oxygen as the sole oxidizing agent.

Abstract: The invention relates to a process for producing hot-seal packs, in particular for transdermal therapeutic systems, by welding to one another, at predetermined linear regions and at polymer layers facing towards one another, two laps of continuous pack material composed of two or more layers. To this end, one (or two) sealing tool(s) are used to bring the pack material into contact with pressure and heat. To improve the quality of the welded seams without altering the cycle rate, according to the invention the sealing time is doubled and the temperature of the sealing tool(s) (1, 2) is reduced so that there is a considerable reduction in the temperature reached within the pack material (3, 4), this temperature then being only slightly above the melting point of the polymer used. An example of a sealing tool (1, 2) is given (FIG. 1).

Abstract: The invention relates to a composite laminate, especially a transdermal therapeutic system (TTS) that contains in at least one layer a component that is sensitive to moisture. Said system further comprises one layer that is spatially separate from said at least one moisture-sensitive layer and that is capable of absorbing moisture. The spatial separation can be achieved by means of a horizontal or vertical separation layer.

Abstract: A process for introducing a plurality of segregated sheet-like administration forms into a dispenser under formation of a multilayered stack for individually dosable removal, with sheet-like tapes wound-up on rolls being present as starting material, utilizes the following steps. In a first step, a number of sheet-like layers of said tapes, which number corresponds to the stack, is simultaneously drawn from a plurality of rolls. In a further step, the individual tapes are united, using guide means, to form a multilayered strand, which in yet another step, is drawn forward to a cutting station where one length of stack is severed at a time, and wherein a length segment of the multilayered strand corresponding to the stack is substantially in the dispenser prior to being severed from a remainder of the multilayered strand by the cutting device.

Abstract: A process for introducing a plurality of segregated sheet-like administration forms into a dispenser under formation of a multilayered stack for individually dosable removal, with sheet-like tapes wound-up on rolls being present as starting material, utilizes the following steps. In a first step, a number of sheet-like layers of said tapes, which number corresponds to the stack, is simultaneously drawn from a plurality of rolls. In a further step, the individual tapes are united, using guide means, to form a multilayered strand, which in yet another step, is drawn forward to a cutting station where one length of stack is severed at a time, and wherein a length segment of the multilayered strand corresponding to the stack is substantially in the dispenser prior to being severed from a remainder of the multilayered strand by the cutting device.

Abstract: A primary packaging unit for film-like or wafer-like administration forms for oral application with an off-cut of an upper web of packaging material and of an lower web of packaging material is characterized in that a plurality of dosage units of a film-like or wafer-like administration form, individually sealed in flat compartments formed without cold or hot forming of the packaging material and spaced at a distance to one another, are present in a primary packaging unit, and there are perforations between the compartments which enable the separation of individual compartments, if necessary.

Abstract: A composition for coloring keratin fibers, containing an indoline, an indole, or a derivative thereof in combination with at least one amino acid or oligopeptide. The composition is useful for coloring human hair and restoring grey hair to its natural color. The formulation can be applied with atmospheric oxygen as the sole oxidizing agent.

Abstract: The invention relates to a method for dispensing flat forms, such as labels, stickers, transdermal therapeutic systems, flat medicaments for oral application, etc, in a controlled manner. According to said method, the outer contour of the flat form (103) is punched out from a strip-shaped starting material and connecting bridges (105) hold the flat form (103) and the edge of the punched layer together. These connecting bridges (105) break when the flat forms are dispensed via a deflector edge (106). The inventive method can be advantageously used for packing individual flat forms in primary packaging. The invention also relates to a specialised punching device used in the method.

Abstract: A composition for coloring keratin fibers, containing an indoline, an indole, or a derivative thereof in combination with at least one amino acid or oligopeptide. The composition is useful for coloring human hair and restoring grey hair to its natural color. The formulation can be applied with atmospheric oxygen as the sole oxidizing agent.

Abstract: A gatherer-stitcher used for gathering various folded sheets is additionally equipped with one or a plurality of devices for applying adhesive, so that the gathered sheets can be bonded to one another directly on the gatherer-stitcher.

Abstract: Process for the production, transport and storage of a therapeutic system which is in the form of a plaster and has an active layer supersaturated with active ingredient and containing the active ingredient in homogeneous dispersion or in solution, characterized in that it is carried out avoiding process parameters which favour or induce crystallization of active ingredient, and any type of pressure operating on the plaster and, in particular, on the active layer is avoided while it is carried out.

Abstract: The present invention relates to a process and a device for the production of a flat administration form comprising a preparation that contains pharmaceutical active substances. The flowable preparation is conveyed to an applicator unit (12) by means of a metering pump, and flows through a distribution chamber (2) having a distribution plate (3) provided with passages (4). This application device (12) transfers the preparation onto a layer of the flat administration form (6,11) which is therefor contacted with the distribution plate (3) for a short time.

Abstract: A process for the continuous production of transdermal therapeutic patches, wherein a laminate of an auxiliary layer (3) siliconized at least on one side, an active substance-containing, pressure-sensitive adhesive layer (4), and a supporting layer (9) is prepared as a strip-shaped web (1) first, and the active substance-containing sections (4') obtained by punching said layers (3) and (4) across the web direction are intermittently transferred onto a second web (2), the punching procedure taking place in the rest phase between the cycles and the transfer procedure onto the second web (2) being carried out preferably at equal distances by means of a transfer device (11, 12), is characterized by the fact that the supporting layer (9) is stripped from the active substance-containing sections (4') during the transfer first, and that then the sections (3') of the auxiliary layer are removed with the aid of a process layer (5) which has been rendered pressure-sensitive adhesive.

Abstract: A tampon printing process which uses a printing plate having at least one printing form at its surface, wherein the printing form is filled with printing medium at time intervals and the printing medium is subsequently transferred from the printing form onto a support by means of a tampon.

Abstract: A toothpaste containing typical components and a combination of silicas and dicalcium phosphate dihydrate (brushite) as its polishing component provides for particularly good restoration of the surface of teeth. This is achieved by controlled remineralization, particularly in scratch marks and dentinal canals. The effect can be enhanced by addition of magnesium ions and/or fluorophosphate ions.

Abstract: Liquid preparations for cleaning hard surfaces based on anionic surfactants either individually or in combination with nonionic surfactants or amphoteric surfactants, or nonionic surfactants either individually or in combination with cationic surfactants, solubilizers and, optionally, builders, dyes, perfumes and preservatives, containing an addition of polymers, namely cellulose ethers.

Abstract: A liquid manual dishwashing detergent composition consisting essentially of alkyl glucoside and dialkyl sulfosuccinate. The composition provides improved detergency and foam stability against proteinaceous soils.

Abstract: This invention is directed to an aqueous, thixotropic dishwater detergent composition which is at room temperature a paste having a viscosity of at least about 30 Pa.s as measured at 20.degree. C. with a rotational viscometer at 5 spindle revolutions per minute, the dishwasher detergent composition comprising:(a) at least one compound with cleaning action or binding capacity for ions causing hardness selected from the group consisting of polyphosphates, aluminosilicates, silicates, hydroxides, and carbonates of sodium or potassium in an amount sufficient to effect cleaning or binding;(b) an active chlorine compound in an amount sufficient to provide active chlorine to the detergent composition; and(c) a thickener compatible with components (a) and (b) in an amount sufficient to give the desired viscosity.

Abstract: Substantially builder-free, liquid, suspension-stable multipurpose cleaning preparations containing abrasives, a surfactant base of mixtures of anionic surfactants or anionic surfactants and amphoteric surfactants, and water, and having a pH-value of from 5.5 to 9.5. These preparations can be used for cleaning hard surfaces of all kinds and in particular can be used as dishwashing detergents, multipurpose cleaners, scouring preparations and/or polishes.

Abstract: A liquid cleaning preparation for hard surfaces comprising an amphoteric polymer compound containing both anionic and cationic centers in the molecular thereof. The polymer is obtained by copolymerization of a cationic vinyl monomer with an anionic vinyl polymer, and in a 0.01% solution of water having a German hardness of 16.degree.d produces irreversible hydrophilization of polyvinyl chloride with increments in the wetting tension of at least 3 mN/m.The preparation may contain an anionic, nonionic, cationic or amphoteric surfactant or mixtures thereof. The polymer compound is present in an amount of from about 0.01% to about 10% by weight, based on the weight of the preparation, and the surfactant is present in a weight ratio of polymer to surfactant of from about 20:1 to about 1:1.