Patents by Inventor Klaus Steiner

Klaus Steiner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Certain derivatives of 1,4-dihydro-5-isopropoxy-1,6-naphthyridine-3-carboxylic acid, pharmaceutical compositions containing them, and methods of using them
    Patent number: 5039679
    Abstract: The present invention concerns the fumaric acid salts of 1,4-dihydro-5-isopropoxy-2-methyl-4-(2-trifluoromethylphenyl) 1,6-naphthyridine-3-carboxylic acid [2-(N-methyl-N-phenylmethylamino)ethyl]ester, processes for preparing them, and pharmaceutical compositions containing them. Methods of using the compounds for treating high blood pressure and diseases of heart and blood vessels.
    Type: Grant
    Filed: February 15, 1990
    Date of Patent: August 13, 1991
    Assignee: Goedecke Aktiengesellschaft
    Inventors: Wolfgang Herrmann, Jurgen Kleinschroth, Klaus Steiner
  • Production of optical isomers of certain 1,6-naphthyridine-3-carboxylate derivatives
    Patent number: 5037987
    Abstract: The present invention provides a process for the separation of the naphthyridine derivatives (.+-.)-1,4-dihydro-5-isopropoxy-2-methyl-4-(2-trifluoromethylphenyl)-1,6-n aphthyridine-3-carboxylic acid ethyl ester and (.+-.)-1,4-dihydro-5-isopropoxy-2-methyl-4-(2-trifluoromethylphenyl)-1,6-n aphthyridine-3-carboxylic acid [2-(N-methyl-N-phenylmethylamino)ethyl] ester into the optical antipodes by use of the (.+-.)-1,4-dihydro-5-isopropoxy-2-methyl-4-(2-trifluoromethylphenyl)-1,6-n aphthyridine-3-carboxylic acid benzyl ester and optically-active O,O'-dibenzoyltartaric acid. Said optical antipodes are calcium antagonists useful in the treatment of blood vessel diseases.
    Type: Grant
    Filed: February 27, 1990
    Date of Patent: August 6, 1991
    Assignee: Goedecke Aktiengesellschaft
    Inventors: Wolfgang Herrmann, Jurgen Kleinschroth, Klaus Steiner
  • Process for producing ebselen in highly pure form
    Patent number: 5008394
    Abstract: The invention is related to a process for preparing highly pure Ebselen (2-phenyl-1.
    Type: Grant
    Filed: August 9, 1989
    Date of Patent: April 16, 1991
    Assignee: A. Nattermann & Cie, GmbH
    Inventors: Bernd-Rainer Gunther, Rainer Losch, Klaus Steiner
  • Process for producing imidazolylthiophenaldehydes
    Patent number: 4720550
    Abstract: The invention is related to a new process for producing imidazolylthiophenaldehydes of the general formula I ##STR1##
    Type: Grant
    Filed: February 6, 1987
    Date of Patent: January 19, 1988
    Assignee: A. Nattermann & CIE GmbH
    Inventors: Bernd-Rainer Gunther, Rainer Losch, Klaus Steiner
  • Process for the production of .beta.-elemonic acid and pharmaceutical preparations containing said acid
    Patent number: 4618605
    Abstract: Disclosed is a process for the production of .beta.-elemonic acid from an alcoholic solution of gum elemi by recovering a crude mixture of elemi acids containing .beta.-elemonic acid, .DELTA..sup.7 .alpha.-elemonic acid and .DELTA..sup.8 .alpha.-elemolic acid by the use of a basic ion exchanger, isomerizing the .DELTA..sup.7 .alpha.-elemolic acid to .DELTA..sup.8 .alpha.-elemolic acid in a chlorinated hydrocarbon by use of a mineral acid, oxidizing the .DELTA..sup.8 .alpha.-elemolic acid to yield additional .beta.-elemonic acid and separating and purifying the total resulting .beta.-elemonic acid from the acid mixture. Also disclosed are pharmaceutical preparations for the treatment of inflammatory conditions containing .beta.-elemonic acid as the active ingredient.
    Type: Grant
    Filed: October 15, 1984
    Date of Patent: October 21, 1986
    Inventors: Gunter Stapel, Karl-Heinz Gober, Sigurd Leyck, Helmut Wetzig, Christian Birkner, Kurt Kesselring, Bruno Christ, Klaus Steiner, Friedhelm Schroder