Patents by Inventor Klaus Unsicker

Klaus Unsicker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of MP52 or MP121 for the treatment and prevention of diseases of the nervous system
    Patent number: 7632808
    Abstract: The present invention concerns the use of biologically active MP52 or/and MP121 for the treatment and prevention of diseases of the nervous system or/and for the treatment of neuropathological situations which are caused by ageing of the nervous system. A pharmaceutical agent according to the invention for the treatment and prevention of diseases of the nervous system or/and for treating neuropathological situations which are caused by ageing of the nervous system therefore contains biologically active MP52 or/and MP121 as the active substance.
    Type: Grant
    Filed: February 3, 2003
    Date of Patent: December 15, 2009
    Assignee: Biopharm Gesellschaft zur Biotechnologischen Entwicklung von Pharmaka
    Inventors: Gertrud Hötten, Jens Pohl, Rolf Bechtold, Michael Paulista, Klaus Unsicker
  • Neuroprotective properties of GDF-15, a novel member of the TGF-Beta superfamily
    Publication number: 20060148709
    Abstract: The present invention relates to a transforming growth factor-beta (TGF-?)-like protein which is derived from neurons and glial cells, and which has a neurotrophic effect on dopaminergic (DAergic) neurons, to nucleic acids coding for the protein, to a vector containing the nucleic acids, to host organisms containing the nucleic acids or the vector, to antibodies directed against the protein, to methods for the production of the nucleic acids, the vector or the protein, to a pharmaceutical composition for the treatment of neurodegenerative disorders in mammals and to a diagnostic kit for the detection of said disorders.
    Type: Application
    Filed: March 9, 2006
    Publication date: July 6, 2006
    Inventors: Klaus Unsicker, Kerstin Krieglstein
  • Cytokines having neurotrophic activity
    Patent number: 6790824
    Abstract: The present invention relates to a pharmaceutical composition having neurotrophic activity, comprising a biologically active amount of at least two cytokines, wherein at least one of said cytokines is BMP, GDF, TGF-&bgr; or GDNF.
    Type: Grant
    Filed: March 17, 2000
    Date of Patent: September 14, 2004
    Assignee: Biopharm Gesellschaft zur biotechnologischen Entwicklung von Pharmaka mbH
    Inventors: Klaus Unsicker, Jens Pohl, Michael Paulista, Rolf Bechtold
  • Use of MP52 or MP121 for the treatment and prevention of diseases of the nervous system
    Publication number: 20030220248
    Abstract: The present invention concerns the use of biologically active MP52 or/and MP121 for the treatment and prevention of diseases of the nervous system or/and for the treatment of neuropathological situations which are caused by ageing of the nervous system. A pharmaceutical agent according to the invention for the treatment and prevention of diseases of the nervous system or/and for treating neuropathological situations which are caused by ageing of the nervous system therefore contains biologically active MP52 or/and MP121 as the active substance.
    Type: Application
    Filed: February 3, 2003
    Publication date: November 27, 2003
    Inventors: Gertrud Hotten, Jens Pohl, Rolf Bechtold, Michael Paulista, Klaus Unsicker
  • Use of MP52 or MP121 for treating and preventing diseases of the nervous system
    Patent number: 6531450
    Abstract: The present invention concerns the use of biologically active MP52 or/and MP121 for the treatment and prevention of diseases of the nervous system or/and for the treatment of neuropathological situations which are caused by ageing of the nervous system. A pharmaceutical agent according to the invention for the treatment and prevention of diseases of the nervous system or/and for treating neuropathological situations which are caused by ageing of the nervous system therefore contains biologically active MP52 or/and MP121 as the active substance.
    Type: Grant
    Filed: May 18, 1998
    Date of Patent: March 11, 2003
    Assignee: Biopharm Gesellschaft zur Biotechnologischen Entwicklung von Pharmaka
    Inventors: Gertrud Hötten, Jens Pohl, Rolf Bechtold, Michael Paulista, Klaus Unsicker
  • USE OF MP52 0R MP121 FOR TREATING AND PREVENTING DISEASES OF THE NERVOUS SYSTEM
    Publication number: 20020045568
    Abstract: The present invention concerns the use of biologically active MP52 or/and MP121 for the treatment and prevention of diseases of the nervous system or/and for the treatment of neuropathological situations which are caused by ageing of the nervous system. A pharmaceutical agent according to the invention for the treatment and prevention of diseases of the nervous system or/and for treating neuropathological situations which are caused by ageing of the nervous system therefore contains biologically active MP52 or/and MP121 as the active substance.
    Type: Application
    Filed: May 18, 1998
    Publication date: April 18, 2002
    Inventors: GERTRUD HOTTEN, JENS POHL, ROLF BECHTOLD, MICHAEL PAULISTA, KLAUS UNSICKER