Abstract: The present invention is directed to the use of a quaternized derivative of polyisobutylene as stabiliser in inverse emulsions like inverse emulsions used for a reverse-phase emulsion polymerisation process, e.g. for the polymerisation of acrylamide and ethylenically unsaturated cationic monomers. Such emulsions are e.g. used as flocculant for waste water treatment. The present invention is further directed to inverse emulsions comprising a quaternized derivative of polyisobutylene. The inverse emulsions have sufficiently low viscosity and sufficiently high shear stability. The present invention is further directed to an inverse emulsion polymerisation process, wherein the inverse emulsion comprises a quaternized derivative of polyisobutylene.

Abstract: A system for measuring a conveyor belt includes a first detector fixed at a location along a path of a conveyor belt. A first signal generator is affixed at a first location of the conveyor belt such that the first signal generator is detectable by the first detector when the first signal generator is in range of the first detector. The first detector is configured to provide a first signal as the first signal generator approaches the first detector. The first detector is configured to provide a second signal as the first signal generator moves away from the first detector. A processor is in electronic communication with the first detector and configured to calculate a belt speed based on an elapsed time between the first signal and the second signal.

Abstract: A method for manufacturing a wet food product for animals can include mixing solid animal feed components with a sauce or sauce components in a temperature-controllable process reactor and sterilising the mixture by heat treatment in the process reactor. The mixing and sterilising can occur at the same time. Embodiments can utilize an apparatus that can include a reactor to receive solid animal feed components and a sauce or sauce components, a temperature control device to control the temperature of the reactor (e.g. at least one wall of the reactor), a mixing device to mix the components located in the reactor (e.g. an agitator within the reactor, etc.), and a control device to control the mixing device to mix the components in the process reactor and to control the temperature control device to sterilise the components or mixture in the reactor.

Abstract: A sound- and heat-insulating enclosure of a pedal mount of a motor vehicle has at least one pedal mounted pivotably thereon. The enclosure has retaining contours, by which fixing on the pedal mount is possible. A pedal-independent high-quality sealing concept can be implemented by shifting a sealing plane between an interior of a cockpit and a footwell from the pedals toward the pedal mount.

Abstract: A sound- and heat-insulating enclosure of a pedal mount of a motor vehicle has at least one pedal mounted pivotably thereon. The enclosure has retaining contours, by which fixing on the pedal mount is possible. A pedal-independent high-quality sealing concept can be implemented by shifting a sealing plane between an interior of a cockpit and a footwell from the pedals toward the pedal mount.

Abstract: Disclosed herein is a method, system, and non-volatile storage medium for simplifying the automation of a process of flow. The method may include determining a machine-independent process model based on data representing a handling of a work tool for performing a process flow. The process flow may include a plurality of sub-processes and the process model may link a process activity with spatial information for each sub-process. The method may also include mapping the machine-independent process model to a machine-specific control model of a machine using a model of the machine. The machine-specific control model may define an operating point of the machine for each sub-process, and the operating point may correspond to the process activity and to the spatial information.

Abstract: A sealing ring of a translationally adjustable component may include a ring body including at least one sealing lip, and a fibre-reinforced reinforcement ring configured to stiffen the ring body in a radial direction and limit a deformation of the at least one sealing lip in the radial direction. The reinforcement ring may be one of i) coupled to the at least one sealing lip, and ii) embedded into the ring body. The reinforcement ring may include laminated carbon fibres and have a modulus of elasticity E2. The ring body may be composed of a plastic having a modulus of elasticity E1. The sealing ring may also have a ratio of the modulus of elasticity E2 to the modulus of elasticity E1 (E2/E1) that is approximately 150 to 300.

Abstract: In an optical-based sample analysis, for example fluorescence-based or absorbance-based measurement, a selection is made between a first excitation light path and a second excitation light path. The first excitation light path directs excitation light from a light source, through an excitation monochromator, through an excitation filter, and to a sample. The second excitation light path directs excitation light from the light source, through the excitation filter, and to the sample while bypassing the excitation monochromator. Excitation light generated by the light source is transmitted along either the first excitation light path or the second excitation light path in accordance with the selection made, thereby irradiating the sample. In response the sample produces emission light (transmitted light in the case of absorbance measurements), which is transmitted to and measured by a light detector.

Abstract: A sealing ring of a translationally adjustable component may include a ring body including at least one sealing lip, and a fibre-reinforced reinforcement ring configured to stiffen the ring body in a radial direction and limit a deformation of the at least one sealing lip in the radial direction. The reinforcement ring may be one of i) coupled to the at least one sealing lip, and ii) embedded into the ring body. The reinforcement ring may include laminated carbon fibres and have a modulus of elasticity E2. The ring body may be composed of a plastic having a modulus of elasticity E1. The sealing ring may also have a ratio of the modulus of elasticity E2 to the modulus of elasticity E1 (E2/E1) that is approximately 150 to 300.

Abstract: In an optical-based sample analysis, for example fluorescence-based or absorbance-based measurement, a selection is made between a first excitation light path and a second excitation light path. The first excitation light path directs excitation light from a light source, through an excitation monochromator, through an excitation filter, and to a sample. The second excitation light path directs excitation light from the light source, through the excitation filter, and to the sample while bypassing the excitation monochromator. Excitation light generated by the light source is transmitted along either the first excitation light path or the second excitation light path in accordance with the selection made, thereby irradiating the sample. In response the sample produces emission light (transmitted light in the case of absorbance measurements), which is transmitted to and measured by a light detector.

Abstract: Anti-DR5 antibody agonists, combined with apoptosis-inducing agents, synergistically induce apoptosis in cancer cells.

Abstract: A method for calibrating a powered actuator for use in a vehicle is provided, with regard to an end position of an actuating element which is easy to achieve and conserves easily damaged mechanical components of the actuator made from plastic, rubber or similar. According to an example embodiement, in a calibrating step, the actuator is operated with recording and analysis of an actuation speed measured parameter such that the actuating element is moved in the direction of the end position and reaching the end position is recognized when the value of the actuation speed measured parameter reaches or drops below a given threshold. A temperature parameter characterizing the temperature of the actuator is evaluated before or during the calibration process. The calibration step is then only carried out if the value of the temperature parameter does not exceed an upper temperature limit. An actuator suitable for carrying out said method is also disclosed.

Abstract: The invention relates to graft polyols with a bimodal particle size distribution and a total solid content of between 5 and 65 wt. %. Said polyols contain small particles with a particle diameter of between 0.05 and 0.7 ?m and large particles with a particle diameter of between 0.4 and 5.0 ?m, whereby the peaks of the large and small particles measured during a representation according to the light-scattering analysis method do not overlap. The total solid content with the defined particle sizes consists of a volumetric fraction of between 5 and 45% small particles and a volumetric fraction of between 95 and 55% large particles, said volumetric fractions totalling 100%. The invention also relates to a method for producing graft polyols of this type and to the use thereof for producing polyurethanes.

Abstract: A method for calibrating a powered actuator for use in a vehicle is provided, with regard to an end position of an actuating element which is easy to achieve and conserves easily damaged mechanical components of the actuator made from plastic, rubber or similar. According to an example embodiement, in a calibrating step, the actuator is operated with recording and analysis of an actuation speed measured parameter such that the actuating element is moved in the direction of the end position and reaching the end position is recognized when the value of the actuation speed measured parameter reaches or drops below a given threshold. A temperature parameter characterizing the temperature of the actuator is evaluated before or during the calibration process. The calibration step is then only carried out if the value of the temperature parameter does not exceed an upper temperature limit. An actuator suitable for carrying out said method is also disclosed.

Abstract: Methods and assays examining expression of one or more biomarkers in a mammalian tissue or cell sample are provided. According to the disclosed methods and assays, detection of the expression of one or more such biomarkers is predictive or indicative that the tissue or cell sample will be sensitive to apoptosis-inducing agents such as Apo2L/TRAIL and anti-DR5 agonist antibodies. Certain biomarkers which may be examined include fucosyltransferases, in particular fucosyltransferase 3 (FUT3) and/or fucosyltransferase 6 (FUT6), as well as sialyl Lewis A and/or X antigens. Kits and articles of manufacture are also provided.

Abstract: Methods and assays examining expression of one or more biomarkers in a mammalian tissue or cell sample are provided. According to the disclosed methods and assays, detection of the expression of one or more such biomarkers is predictive or indicative that the tissue or cell sample will be sensitive to apoptosis-inducing agents such as Apo2L/TRAIL and anti-DR5 agonist antibodies. Certain biomarkers which may be examined include fucosyltransferases, in particular fucosyltransferase 3 (FUT3) and/or fucosyltransferase 6 (FUT6), as well as sialyl Lewis A and/or X antigens. Kits and articles of manufacture are also provided.

Abstract: Anti-DR4 or Anti-DR5 antibody agonists, combined with apoptosis-inducing agents, synergistically induce apoptosis in cancer cells.

Abstract: Anti-DR5 antibody agonists, combined with apoptosis-inducing agents, synergistically induce apoptosis in cancer cells.

Abstract: The invention relates to a bicyclic oligopeptide or ester thereof having the capability to inhibit the glucagon receptor, comprised of: (a) a first cyclic group, which comprises at least one cysteine group and is formed by an amide bonding of the N-terminal amino acid with the second carboxylate group of a diacid amino acid, and (b) a second cyclic group which is formed by an amide bonding of an amino acid with the ?-carboxylate group of said diacid amino acid, and by a disulfide bonding of the C-terminal cysteine and a cysteine group within the first cyclic group (a); and to the use of such bicyclic oligopeptides for the preparation of a medicament for the treatment or prevention of diseases, in which glucagon receptors are involved.

Abstract: The invention relates to graft polyols with a bimodal particle size distribution and a total solid content of between 5 and 65 wt. %. Said polyols contain small particles with a particle diameter of between 0.05 and 0.7 ?m and large particles with a particle diameter of between 0.4 and 5.0 ?m, whereby the peaks of the large and small particles measured during a representation according to the light-scattering analysis method do not overlap. The total solid content with the defined particle sizes consists of a volumetric fraction of between 5 and 45% small particles and a volumetric fraction of between 95 and 55% large particles, said volumetric fractions totalling 100%. The invention also relates to a method for producing graft polyols of this type and to the use thereof for producing polyurethanes.