Abstract: The present invention relates to novel pyridine-N oxide substituted 2-formamido (N-phenyl and N-pyridyl) acetamide compounds that are Interleukin-17 (IL-17) inhibitors, processes for their preparation, pharmaceutical compositions, and medicaments containing them, and their use in diseases and disorders mediated by IL-17.

Abstract: An operating apparatus for a vehicle component comprises an operating panel (12) as well as an electric motor (34) mechanically coupled thereto with an unbalance mass. A detector (20) can capture the contact of the operating panel (12) by a user. A sensor (46) is provided in order to set exactly the number of revolutions of the electric motor in response to the contact of the operating panel by a user. The number of revolutions of the rotor is determined via this sensor.

Abstract: An operating apparatus for a vehicle component comprises an operating panel (12) as well as an electric motor (34) mechanically coupled thereto with an unbalance mass. A detector (20) can capture the contact of the operating panel (12) by a user. A sensor (46) is provided in order to set exactly the number of revolutions of the electric motor in response to the contact of the operating panel by a user. The number of revolutions of the rotor is determined via this sensor.

Abstract: An operating system for a motor vehicle has an operating surface with at least one operating area that is indicated by a symbol system on the operating surface, a touch sensor system by means of which a touch of the operating area is detectable, a drive for generating a haptic feedback by a movement of the operating surface, a drive frame which connects the drive to the operating surface in a force-transmitting manner, and an operating system carrier relative to which the operating surface is movable for generating the haptic feedback. An elastically pretensioned mounting is provided between the drive frame and the operating system carrier.

Abstract: The present invention relates to pyrazolo pyrimidine derivatives, to methods of preparing these, to combinations and pharmaceutical composition comprising these, and to their use in the treatment of diseases and disorders which may for example involve autoimmune diseases, angiogenesis, pain, and/or inflammatory diseases.

Abstract: The invention relates to a method for the production of a drop-forged balancing shaft for a mass balancing gear of an internal combustion engine. The balancing shaft has an unbalanced plane formed by the rotational axis thereof and an eccentric mass center of gravity, and at least one bearing journal, the outer lateral surface of which serves as a track for a rolling bearing supporting the balancing shaft in the internal combustion engine. To this end, the balancing shaft is to be forged in a forging die having a parting plane extending in the direction of the rotational axis and rotated in relation to the unbalanced plane.

Abstract: The present invention relates to pyrazolo pyrimidine derivatives, to methods of preparing these, to combinations and pharmaceutical composition comprising these, and to their use in the treatment of diseases and disorders which may for example involve autoimmune diseases, angiogenesis, pain, and/or inflammatory diseases.

Abstract: An amine, which is substituted by phenyl-substituted pyrimidin; and phenyl; and a third substituent and its use as an immunoglobulin E (IgE) inhibitor.

Abstract: The invention relates to a method for the production of a drop-forged balancing shaft for a mass balancing gear of an internal combustion engine. The balancing shaft has an unbalanced plane formed by the rotational axis thereof and an eccentric mass center of gravity, and at least one bearing journal, the outer lateral surface of which serves as a track for a rolling bearing supporting the balancing shaft in the internal combustion engine. To this end, the balancing shaft is to be forged in a forging die having a parting plane extending in the direction of the rotational axis and rotated in relation to the unbalanced plane.

Abstract: A compound of formula (I), wherein substituents are as given above, useful in the treatment of a disease mediated by the action of CCR3.

Abstract: The invention relates to novel imidazopyridine derivatives and to their use in the treatment of diseases and disorders which may e.g. involve angiogenesis and/or pain, including autoimmune and inflammatory diseases.

Abstract: A vehicle steering wheel (20) includes a movable airbag module (24) which can be depressed by a limited axial stroke for generating a horn signal. The vehicle steering wheel (20) further includes a sensor system (22a, 22b) operating in a contactless manner for determining the stroke.

Abstract: A compound of formula (I), wherein substituents are as given above, useful in the treatment of a disease mediated by the action of CCR3, in particular inflammatory or obstructive airway diseases.

Abstract: The use of a metathesis catalyst in the preparation of a functionalized sphingolipid.

Abstract: The use of compound of formula I in the preparation of a medicament, e.g. for the treatment of condition mediated by CCR3.

Abstract: Analogues of the amino acid sequence KAPREKY and their use in screening for compounds which interacts with Fc?RI?.

Abstract: An amine, which is substituted by phenyl-substituted pyrimidin; and phenyl; and a third substituent and its use as an immunoglobulin E (IgE) inhibitor.

Abstract: A device for determining an absolute angle of rotation of a rotational axis has a first measuring device for measuring an angle of rotation in a limited first measuring range and a second measuring device for determining an absolute angle range. The second measuring device transforms a rotation of the rotational axis into a linear shift.

Abstract: Analogues of the amino acid sequence KAPREKY and their use in screening for compounds which interacts with Fc?RI?.

Abstract: A device for determining an absolute angle of rotation of a rotation axis (12) includes a first measurement arrangement for measuring an angle of rotation in a limited first measurement range and a second measurement arrangement for determining an absolute angle range. The second measurement arrangement comprises a deflection element (20) and a rotation element. The deflection element undergoes a deflection dependent on the rotation of the rotation axis (12). The deflection, in turn, is converted into a rotation of the rotation element (22).