Abstract: A process for the preparation of an anthranilamide of the formula ##STR1## in which R.sub.1 and R.sub.2 each independently is hydrogen orC.sub.1 to C.sub.4 alkyl, or R.sub.1 and R.sub.2, together with the nitrogen atom to which they are bonded, form a heterocyclic ring,comprising reacting isatoic anhydride of the formula ##STR2## with an approximately equimolar amount of an amine of the formula ##STR3## in water at a pH of about 7 to 10.5 and a temperature of about 20.degree. to 100.degree. C. Advantageously the reaction is effected in the presence of a buffer system comprising an amine of the formula ##STR4## plus at least one of a hydrohalide and carbonic acid salt of such amine, e.g. ammonia or a lower alkyl amine plus the corresponding hydrochloride and/or carbonate.