Patents by Inventor Knut Bertil Hogberg

Knut Bertil Hogberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4029778
    Abstract: New 21-esters of corticoid steroid hormones, the esters having an antitumor activity, are prepared by reacting a reactive derivative of the general formula ##STR1## wherein R.sup.1 can be hydrogen, lower alkyl, halogen, or lower alkoxy, X can be oxygen, sulphur, or a monovalent carbon-to-carbon bond, A can be alkylene, aminoalkylene, or lower-alkanoyl aminoalkylene, and A together with X also can be a monovalent carbon-to-carbon bond, with a corticoid steroid.
    Type: Grant
    Filed: March 13, 1973
    Date of Patent: June 14, 1977
    Assignee: Aktiebolaget Leo
    Inventors: Hans Jacob Fex, Knut Bertil Hogberg, Imre Konyves
  • Patent number: 3991187
    Abstract: Novel symmetrical secondary phosphoric acid esters having the general formula ##SPC1##Wherein the substituent R is positioned in meta or para position relative to the phosphoric acid ester group; processes for the preparation of said esters; and compositions containing said esters. The esters are i.a. useful as selective inhibitors of prostaglandins and compounds with prostaglandin activities. They also selectively antagonize the slow reacting substance (SRS).
    Type: Grant
    Filed: May 6, 1974
    Date of Patent: November 9, 1976
    Assignee: Aktiebolaget Leo
    Inventors: Knut Bertil Hogberg, Hans Jacob Fex, B. Goran Fredholm, Torsten Rune Perklev, Sten Gunnar Veige
  • Patent number: 3963707
    Abstract: This invention relates to novel N-halogenoalkyl-N-nitroso carbamates and N.sup.4 halogenalkyl-N.sup.4 -nitroso allophanates of steroid compounds, having an anti-tumor activity, and to the preparation thereof. The invention is also concerned with pharmaceutical compositions containing the said compounds, and methods of treatment therewith.
    Type: Grant
    Filed: February 25, 1974
    Date of Patent: June 15, 1976
    Assignee: Aktiebolaget Leo
    Inventors: Knut Bertil Hogberg, Hans Jacob Fex, Imre Konyves, Anders Robert Stamvik
  • Patent number: RE29199
    Abstract: .Iadd.Antitumor active mono and poly N-Bis-(B-haloethyl)-carbamic acid esters of certain estrogenic steroid hormones, especially estradiol; such compounds wherein all hydroxyl groups of the steroid molecule are not thus esterified; and organic and inorganic acid esters of such latter compounds. .Iaddend.
    Type: Grant
    Filed: July 30, 1976
    Date of Patent: May 3, 1977
    Assignee: Aktiebolaget Leo
    Inventors: Hans Jakob Fex, Knut Bertil Hogberg, Imre Konyves, Paul Hans Otto Joseph Kneip
  • Patent number: RE29202
    Abstract: Novel symmetrical secondary phosphoric acid esters having the general formula ##STR1## wherein the substituent R is positioned in meta or para position relative to the phosphoric acid ester group; processes for the preparation of said esters; and compositions containing said esters. The esters are i.a. useful as selective inhibitors of prostaglandins and compounds with prostaglandin activities. They also selectively antagonize the slow reacting substance (SRS).
    Type: Grant
    Filed: August 4, 1976
    Date of Patent: May 3, 1977
    Assignee: Aktiebolaget Leo
    Inventors: Knut Bertil Hogberg, Hans Jacob Fex, Bo Goran Fredholm, Torsten Rune Perklev, Sten Gunnar Veige