Patents by Inventor Knut Burgdorf

Knut Burgdorf has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Enzyme for the preparation of 1-amino-4-(hydroxymethyl)-2-cyclopentene derivatives
    Patent number: 7405065
    Abstract: The invention relates to a novel process for the preparation of (1R,4S)- or (1S,4R)-1-amino-4-(hydroxy-methyl)-2-cyclopentene of the formulae and/or of (1S,4R)- or (1R,4S)-amino alcohol derivatives of the general formulae and to novel microorganisms which are able to utilize a cyclopentene derivative of the general formula as sole nitrogen source, as sole carbon source or as sole carbon and nitrogen source.
    Type: Grant
    Filed: July 21, 2004
    Date of Patent: July 29, 2008
    Assignee: Lonza AG
    Inventors: Christine Bernegger-Egli, Olwen M. Birch, Pierre Bossard, Walter Brieden, Frank Brux, Knut Burgdorf, Laurent Duc, Kay-Sarah Etter, Yves Guggisberg, Martin Sauter, Eva Maria Urban
  • Process for the preparation of amino alcohols and derivatives thereof
    Publication number: 20040265985
    Abstract: The invention relates to a novel process for the preparation of (1R,4S)- or (1S,4R)-1-amino-4-(hydroxymethyl)-2-cyclopentene of the formulae 1
    Type: Application
    Filed: July 21, 2004
    Publication date: December 30, 2004
    Inventors: Christine Bernegger-Egli, Olwen M. Birch, Pierre Bossard, Walter Brieden, Frank Brux, Knut Burgdorf, Laurent Duc, Kay-Sarah Etter, Yves Guggisberg, Martin Sauter, Eva Maria Urban
  • Process for the preparation of amino alcohols and derivatives thereof and microorganisms useful in process
    Patent number: 6787347
    Abstract: The invention relates to a novel process for the preparation of (1R,4S)- or (1S,4R)-1-amino-4-(hydroxymethyl)-2-cyclopentene of the formulae and/or of (1S,4R)- or (1R,4S)-amino alcohol derivatives of the general formulae and to novel microorganisms which are able to utilize a cyclopentene derivative of the general formula as sole nitrogen source, as sole carbon source or as sole carbon and nitrogen source.
    Type: Grant
    Filed: November 14, 2001
    Date of Patent: September 7, 2004
    Assignee: LONZA AG
    Inventors: Christine Bernegger-Egli, Olwen M. Birch, Pierre Bossard, Walter Brieden, Frank Brux, Knut Burgdorf, Laurent Duc, Kay-Sarah Etter, Yves Guggisberg, Martin Sauter, Eva Maria Urban
  • Process for the preparation of amino alcohols and derivatives thereof
    Publication number: 20030008360
    Abstract: The invention relates to a novel process for the preparation of (1R,4S)- or (1S,4R)-1-amino-4-(hydroxymethyl)-2-cyclopentene of the formulae 1
    Type: Application
    Filed: November 14, 2001
    Publication date: January 9, 2003
    Inventors: Christine Bernegger-Egli, Olwen M. Birch, Pierre Bossard, Walter Brieden, Frank Brux, Knut Burgdorf, Laurent Duc, Kay-Sarah Etter, Yves Guggisberg, Martin Sauter, Eva Maria Urban
  • Process for the preparation of amino alcohols and derivatives thereof
    Patent number: 6368850
    Abstract: The invention relates to a novel process for the preparation of (1R,4S)- or (1S,4R)-1-amino-4-(hydroxymethyl)-2-cyclopentene of the formulae and/or of (1S,4R)- or (1R,4S)-amino alcohol derivatives of the general formulae and to novel microorganisms which are able to utilize a cyclopentene derivative of the general formula as sole nitrogen source, as sole carbon source or as sole carbon and nitrogen source. The invention further relates to enzyme extracts and enzymes having N-acetylamino-alcohol hydrolase activity obtainable from these microorganisms.
    Type: Grant
    Filed: May 21, 1999
    Date of Patent: April 9, 2002
    Assignee: Lonza AG
    Inventors: Christine Bernegger-Egli, Olwen M. Birch, Pierre Bossard, Walter Brieden, Frank Brux, Knut Burgdorf, Laurent Duc, Kay-Sarah Etter, Yves Guggisberg, Martin Sauter, Eva Maria Urban
  • Enantiomer compositions of (1R,4S)-1-butyrylamino-4-(hydroxymethyl)-2-cyclopentene
    Patent number: 6137007
    Abstract: A novel process for the preparation of (1S,4R)- or (1R,4S)-4-(2-amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol of the formulae ##STR1## is described. This entails in the first stage (.+-.)-2-azabicyclo[2.2.1]hept-5-en-3-one of the formula ##STR2## being acylated to give a (.+-.)-2-azabicyclo[2.2.1]hept-5-en-3-one derivative of the general formula ##STR3## in which R.sup.1 denotes C.sub.1-4 -alkyl, C.sub.1-4 -alkoxy, aryl or aryloxy, the latter being reduced in the second stage to give a cyclopentene derivative of the general formula ##STR4## in which R.sup.
    Type: Grant
    Filed: August 13, 1999
    Date of Patent: October 24, 2000
    Assignee: Lonza AG
    Inventors: Christine Bernegger, Eva Maria Urban, Olwen Mary Birch, Knut Burgdorf, Frank Brux, Kay-Sara Etter, Pierre Bossard, Walter Brieden, Laurent Duc, John Gordon, Colm O'Murchu, Yves Guggisberg
  • Microorganisms for the stabilization of plasmids
    Patent number: 6057146
    Abstract: New microorganisms with plasmids stable relative to betaine use. These new microorganisms contain (a) a hybrid plasmid with a DNA fragment that contains a genetic sequence that codes for the use of betaine and (b) a mutation in the chromosomal gene coding for the betaine use.
    Type: Grant
    Filed: January 29, 1999
    Date of Patent: May 2, 2000
    Assignee: Lonza AG
    Inventors: Thomas Zimmermann, Cristiana Boraschi, Knut Burgdorf, Catherine Caubere
  • Microorganisms for the stabilization of plasmids
    Patent number: 5891710
    Abstract: New microorganisms with plasmids stable relative to betaine utilization. These new microorganisms contain (a) a hybrid plasmid with a DNA fragment that contains a genetic sequence that codes for betaine utilization and (b) a mutation in the chromosomal gene coding for the betaine utilization.
    Type: Grant
    Filed: July 21, 1997
    Date of Patent: April 6, 1999
    Assignee: Lonza Ltd.
    Inventors: Thomas Zimmermann, Cristiana Boraschi, Knut Burgdorf, Catherine Caubere