Patents by Inventor Knut Irgum

Knut Irgum has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090326081
    Abstract: The invention relates to a polymeric material comprising crosslinked spherical particles that are obtained by photoinitiated precipitation polymerization of crosslinking monomer and optionally a further monomer in the presence of an initiator and a solvent. It also relates to a method for producing the material and a chromatography column containing the material.
    Type: Application
    Filed: June 8, 2007
    Publication date: December 31, 2009
    Applicant: SEQUANT AB
    Inventors: Knut Irgum, Fredrik Lime
  • Patent number: 7632389
    Abstract: A novel open tube with a zwitterionic betaine polymer layer can be prepared by initiated grafting polymerization. This open tube can be used for separating inorganic anions, peptides and proteins. A capillary electrophoresis method and a capillary chromatography method use the novel open tube. There are methods for manufacturing the novel open tube.
    Type: Grant
    Filed: April 7, 2004
    Date of Patent: December 15, 2009
    Assignee: Merck Patent GmbH
    Inventors: Jiang Wen, Knut Irgum
  • Patent number: 7238426
    Abstract: A porous silica particle suitable can be used in zwitterionic high performance liquid chromatography. The particle comprises covalently bound zwitterionic groups grafted through a polymerization reaction. A hydrophilic column packing material suitable for use as a stationary phase in zwitterionic high performance liquid chromatography may comprise porous silica particles. The particles may comprise covalently bound zwitterionic groups. Methods for manufacturing and applying the silica particles exist.
    Type: Grant
    Filed: August 13, 2004
    Date of Patent: July 3, 2007
    Assignee: Sequant AB
    Inventors: Wen Jiang, Knut Irgum
  • Patent number: 7025886
    Abstract: The present invention provides porous monoliths with high flow permeability that can be produced by polymerising and divinylbenzene in the presence of an initiator, a carboxy-functionalized nitroxide stable free radical and polymeric porogens. The monoliths produced with these stable free radicals functionalized with carboxylic groups feature porosities very different from those produced by polymerizations involving other SFRs, characterized by very large surface areas in combination with relatively large through-pores. The invention also provides a method for producing the monoliths, a column containing the monoliths and an assay method using the column.
    Type: Grant
    Filed: March 25, 2002
    Date of Patent: April 11, 2006
    Assignee: Sequant AB
    Inventors: Camilla Viklund, Knut Irgum
  • Patent number: 6884345
    Abstract: A novel sorbent suitable for use as a stationary phase in a chromatography column, the core of which consists of an organic polymer of synthetic or natural origin. Further, the carrier exhibits a plurality of covalently bonded non-aromatic zwitterionic groups on its surface. Additionally, the invention also relates to a method for purifying a particular biological macromolecule, such as a protein or a nucleic acid, by zwitterionic ion exchange chromatography as well as an ion exchange column suitable for use in the zwitterionic ion exchange chromatography.
    Type: Grant
    Filed: November 9, 1999
    Date of Patent: April 26, 2005
    Inventors: Knut Irgum, Camilla Viklund
  • Publication number: 20050064192
    Abstract: A porous silica particle suitable can be used in zwitterionic high performance liquid chromatography. The particle comprises covalently bound zwitterionic groups grafted through a polymerization reaction. A hydrophilic column packing material suitable for use as a stationary phase in zwitterionic high performance liquid chromatography may comprise porous silica particles. The particles may comprise covalently bound zwitterionic groups. Methods for manufacturing and applying the silica particles exist.
    Type: Application
    Filed: August 13, 2004
    Publication date: March 24, 2005
    Applicant: SEQUANT AB
    Inventors: Wen Jiang, Knut Irgum
  • Publication number: 20040256232
    Abstract: A novel open tube with a zwitterionic betaine polymer layer can be prepared by initiated grafting polymerization. This open tube can be used for separating inorganic anions, peptides and proteins. A capillary electrophoresis method and a capillary chromatography method use the novel open tube. There are methods for manufacturing the novel open tube.
    Type: Application
    Filed: April 7, 2004
    Publication date: December 23, 2004
    Inventors: Wen Jiang, Knut Irgum
  • Publication number: 20040138432
    Abstract: The present invention provides porous monoliths with high flow permeability that can be produced by polymerising and divinylbenzene in the presence of an initiator, a carboxy-functionalized nitroxide stable free radical and polymeric porogens. The monoliths produced with these stable free radicals functionalized with carboxylic groups feature porosities very different from those produced by polymerizations involving other SFRs, characterized by very large surface areas in combination with relatively large through-pores. The invention also provides a method for producing the monoliths, a column containing the monoliths and an assay method using the column.
    Type: Application
    Filed: March 10, 2004
    Publication date: July 15, 2004
    Inventors: Camilla Viklund, Knut Irgum
  • Patent number: 4666856
    Abstract: A method of measuring a content of a compound such as gaseous sulfur dioxide in air comprising adsorbing the compound on a solid adsorbent, including a carrier consisting of a solid buffer of a partially regenerated ion exchanger.In addition the solid adsorbent may comprise a stabilizer which is either a stabilizer for the compound intended to be adsorbed on the adsorbent or a stabilizer for a reaction product thereof formed in the adsorption.
    Type: Grant
    Filed: July 13, 1984
    Date of Patent: May 19, 1987
    Inventors: Knut Irgum, Mats J. Lindgren