Patents by Inventor Knut Meyer

Knut Meyer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240109850
    Abstract: The present invention includes compounds of formula (I) and methods for its preparation and treatment of disorders with activated peroxisome preoliferator-activated receptor gamma (PPARG), particularly cancer.
    Type: Application
    Filed: August 31, 2023
    Publication date: April 4, 2024
    Applicants: Bayer Aktiengesellschaft, The Broad Institute, Inc., Dana-Farber Cancer Institute, Inc.
    Inventors: Knut EIS, Elisabeth POOK, Ulf BRÜGGEMEIER, Adelaide Clara F. A. DE LEMOS, Sven CHRISTIAN, Isabel Sophie JERCHEL-FURAU, Ulrike RAUH, Nico BRÄUER, Timo STELLFELD, Anders Roland FRIBERG, Christian LECHNER, Stefan KAULFUSS, Hanna MEYER, Charlotte Christine KOPITZ, Steven James FERRARA, Jonathan GOLDSTEIN, Matthew MEYERSON, Christopher LEMKE, Timothy A. LEWIS
  • Publication number: 20230380373
    Abstract: Soybean plants producing soybean seeds comprising leghemoglobin are produced by modifying the genome of the soybean plant. Soybean plants, soybean seeds and soy protein compositions comprising leghemoglobin are provided. Soybean plants, soybean seeds and soy protein compositions comprising leghemoglobin and additionally one or more of high oleic acid, low linolenic acid, high protein, low stachyose, low raffinose and low protease inhibitors are provided. Protein compositions comprising leghemoglobin, such as soy isolates and concentrates can be made from the soybean seeds. Additionally, methods for generating and using plants, seeds and protein compositions comprising leghemoglobin are disclosed.
    Type: Application
    Filed: October 22, 2021
    Publication date: November 30, 2023
    Applicant: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: HYEON-JE CHO, JOHN D. EVERARD, ANTHONY KINNEY, ZHAN-BIN LIU, KNUT MEYER, THOMAS G. PATTERSON, KEVIN G. RIPP, BO SHEN
  • Publication number: 20230348928
    Abstract: The present disclosure relates to the field of plant molecular biology, more particularly to regulation of gene expression in plants.
    Type: Application
    Filed: August 4, 2021
    Publication date: November 2, 2023
    Applicant: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: PRIYANKA BHYRI, NANDINI DASGUPTA, KRUPA DESHMUKH, SCOTT DIEHN, KNUT MEYER, GILDA RAUSCHER, KEVIN G. RIPP, LYNNE EILEEN SIMS
  • Publication number: 20230227843
    Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.
    Type: Application
    Filed: January 31, 2023
    Publication date: July 20, 2023
    Applicant: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: ALBERT L LU, KNUT MEYER, GILDA RAUSCHER, GUSUI WU
  • Publication number: 20220340923
    Abstract: Soybean plants producing soybean seeds comprising leghemoglobin are produced by modifying the genome of the soybean plant. Soybean plants, soybean seeds and soy protein compositions comprising leghemoglobin are provided. Soybean plants, soybean seeds and soy protein compositions comprising leghemoglobin and additionally one or more of high oleic acid, low linolenic acid, high protein, low stachyose, low raffinose and low protease inhibitors are provided. Protein compositions comprising leghemoglobin, such as soy isolates and concentrates can be made from the soybean seeds. Additionally, methods for generating and using plants, seeds and protein compositions comprising leghemoglobin are disclosed.
    Type: Application
    Filed: June 30, 2022
    Publication date: October 27, 2022
    Applicant: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: HYEON-JE CHO, JOHN D EVERARD, ANTHONY J. KINNEY, ZHAN-BIN LIU, KNUT MEYER, THOMAS G PATTERSON, KEVIN G RIPP, BO SHEN
  • Publication number: 20220325295
    Abstract: Compositions and methods related to transgenic high oleic acid/ALS inhibitor-tolerant soybean plants are provided. Specifically, the present invention provides soybean plants having a DP-305423-1 event which imparts a high oleic acid phenotype and tolerance to at least one ALS-inhibiting herbicide. The soybean plant harboring the DP-305423-1 event comprises genomic/transgene junctions having at least the polynucleotide sequence of SEQ ID NO:8, 9, 14, 15, 20, 21, 83 or 84. The characterization of the genomic insertion site of the DP-305423-1 event provides for an enhanced breeding efficiency and enables the use of molecular markers to track the transgene insert in the breeding populations and progeny thereof. Various methods and compositions for the identification, detection, and use of the soybean DP-305423-1 events are provided.
    Type: Application
    Filed: June 16, 2022
    Publication date: October 13, 2022
    Applicant: E. I. DU PONT DE NEMOURS AND COMPANY
    Inventors: KENT BRINK, ROBERT F CRESSMAN, Jr., ANTHONY J KINNEY, KNUT MEYER, KEVIN L STECCA, NATALIE N WEBER, CATHY XIAOYAN ZHONG
  • Patent number: 11390875
    Abstract: Compositions and methods related to transgenic high oleic acid/ALS inhibitor-tolerant soybean plants are provided. Specifically, the present invention provides soybean plants having a DP-305423-1 event which imparts a high oleic acid phenotype and tolerance to at least one ALS-inhibiting herbicide. The soybean plant harboring the DP-305423-1 event comprises genomic/transgene junctions having at least the polynucleotide sequence of SEQ ID NO:8, 9, 14, 15, 20, 21, 83 or 84. The characterization of the genomic insertion site of the DP-305423-1 event provides for an enhanced breeding efficiency and enables the use of molecular markers to track the transgene insert in the breeding populations and progeny thereof. Various methods and compositions for the identification, detection, and use of the soybean DP-305423-1 events are provided.
    Type: Grant
    Filed: July 13, 2020
    Date of Patent: July 19, 2022
    Inventors: Kent Brink, Robert F Cressman, Jr., Anthony J Kinney, Knut Meyer, Kevin L Stecca, Natalie N Weber, Cathy Xiaoyan Zhong
  • Patent number: 11359206
    Abstract: Soybean plants producing soybean seeds comprising leghemoglobin are produced by modifying the genome of the soybean plant. Soybean plants, soybean seeds and soy protein compositions comprising leghemoglobin are provided. Soybean plants, soybean seeds and soy protein compositions comprising leghemoglobin and additionally one or more of high oleic acid, low linolenic acid, high protein, low stachyose, low raffinose and low protease inhibitors are provided. Protein compositions comprising leghemoglobin, such as soy isolates and concentrates can be made from the soybean seeds. Additionally, methods for generating and using plants, seeds and protein compositions comprising leghemoglobin are disclosed.
    Type: Grant
    Filed: December 21, 2021
    Date of Patent: June 14, 2022
    Inventors: Hyeon-Je Cho, John D Everard, Anthony J Kinney, Zhan-Bin Liu, Knut Meyer, Thomas G Patterson, Kevin G Ripp, Bo Shen
  • Patent number: 11319549
    Abstract: Recombinant DNA constructs comprising the soybean sucrose synthase promoter operably linked to polynucleotides encoding transcription factors such as ODP1, Lec1 and FUSCA3 are disclosed. These constructs are used for increasing oil content while maintaining normal germination in oilseed plants. Methods to increase oil content in the seeds of an oilseed plant using this construct are also disclosed herein.
    Type: Grant
    Filed: November 16, 2020
    Date of Patent: May 3, 2022
    Inventors: Howard Glenn Damude, Bryce Reid Daines, Knut Meyer, Kevin G Ripp, Kevin L Stecca
  • Publication number: 20220127631
    Abstract: Soybean plants producing soybean seeds comprising leghemoglobin are produced by modifying the genome of the soybean plant. Soybean plants, soybean seeds and soy protein compositions comprising leghemoglobin are provided. Soybean plants, soybean seeds and soy protein compositions comprising leghemoglobin and additionally one or more of high oleic acid, low linolenic acid, high protein, low stachyose, low raffinose and low protease inhibitors are provided. Protein compositions comprising leghemoglobin, such as soy isolates and concentrates can be made from the soybean seeds. Additionally, methods for generating and using plants, seeds and protein compositions comprising leghemoglobin are disclosed.
    Type: Application
    Filed: October 22, 2021
    Publication date: April 28, 2022
    Applicant: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: HYEON-JE CHO, JOHN D EVERARD, ANTHONY J KINNEY, ZHAN-BIN LIU, KNUT MEYER, THOMAS G PATTERSON, KEVIN G RIPP, BO SHEN
  • Publication number: 20220127632
    Abstract: Soybean plants producing soybean seeds comprising leghemoglobin are produced by modifying the genome of the soybean plant. Soybean plants, soybean seeds and soy protein compositions comprising leghemoglobin are provided. Soybean plants, soybean seeds and soy protein compositions comprising leghemoglobin and additionally one or more of high oleic acid, low linolenic acid, high protein, low stachyose, low raffinose and low protease inhibitors are provided. Protein compositions comprising leghemoglobin, such as soy isolates and concentrates can be made from the soybean seeds. Additionally, methods for generating and using plants, seeds and protein compositions comprising leghemoglobin are disclosed.
    Type: Application
    Filed: December 21, 2021
    Publication date: April 28, 2022
    Applicant: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: HYEON-JE CHO, JOHN D EVERARD, ANTHONY J KINNEY, ZHAN-BIN LIU, KNUT MEYER, THOMAS G PATTERSON, KEVIN G RIPP, BO SHEN
  • Publication number: 20220090111
    Abstract: This disclosure concerns compositions and methods for promoting transcription of a nucleotide sequence in a plant or plant cell, employing a promoter from a GmCAB2 gene. Some embodiments relate to a promoter or a 5? UTR from a GmCAB2 gene that functions in plants to promote transcription of operably linked nucleotide sequences. Other embodiments relate to a 3? UTR or a terminator from a GmCAB2 gene that functions in plants to promote transcription of operably linked nucleotide sequences.
    Type: Application
    Filed: November 30, 2021
    Publication date: March 24, 2022
    Applicants: CORTEVA AGRISCIENCE LLC, PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: Lyudmila Sidorenko, Cory M. Larsen, Geny Anthony, Shreedharan Sriram, Holly Jean Butler, Lynne E. Sims, Scott H. Diehn, Gilda M. Rauscher, Kevin G. Ripp, Knut Meyer
  • Patent number: 11225670
    Abstract: This disclosure concerns compositions and methods for promoting transcription of a nucleotide sequence in a plant or plant cell, employing a promoter from a GmCAB2 gene. Some embodiments relate to a promoter or a 5? UTR from a GmCAB2 gene that functions in plants to promote transcription of operably linked nucleotide sequences. Other embodiments relate to a 3? UTR or a terminator from a GmCAB2 gene that functions in plants to promote transcription of operably linked nucleotide sequences.
    Type: Grant
    Filed: October 29, 2018
    Date of Patent: January 18, 2022
    Assignees: Corteva Agriscience LLC, Pioneer Hi-Bred International, Inc.
    Inventors: Lyudmila Sidorenko, Cory M. Larsen, Geny Anthony, Shreedharan Sriram, Holly Jean Butler, Lynne E. Sims, Scott H. Diehn, Gilda M. Rauscher, Kevin G. Ripp, Knut Meyer
  • Publication number: 20210062209
    Abstract: Recombinant DNA constructs comprising the soybean sucrose synthase promoter operably linked to polynucleotides encoding transcription factors such as ODP1, Lec1 and FUSCA3 are disclosed. These constructs are used for increasing oil content while maintaining normal germination in oilseed plants. Methods to increase oil content in the seeds of an oilseed plant using this construct are also disclosed herein.
    Type: Application
    Filed: November 16, 2020
    Publication date: March 4, 2021
    Applicants: E. I. DU PONT DE NEMOURS AND COMPANY, PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: HOWARD GLENN DAMUDE, BRYCE REID DAINES, KNUT MEYER, KEVIN G RIPP, KEVIN L STECCA
  • Patent number: 10876128
    Abstract: Recombinant DNA constructs comprising the soybean sucrose synthase promoter operably linked to polynucleotides encoding transcription factors such as ODP1, Lec1 and FUSCA3 are disclosed. These constructs are used for increasing oil content while maintaining normal germination in oilseed plants. Methods to increase oil content in the seeds of an oilseed plant using this construct are also disclosed herein.
    Type: Grant
    Filed: June 27, 2018
    Date of Patent: December 29, 2020
    Inventors: Howard Glenn Damude, Bryce Daines, Knut Meyer, Kevin G. Ripp, Kevin L. Stecca
  • Publication number: 20200347395
    Abstract: This disclosure concerns compositions and methods for promoting transcription of a nucleotide sequence in a plant or plant cell, employing a promoter from a GmCAB2 gene. Some embodiments relate to a promoter or a 5? UTR from a GmCAB2 gene that functions in plants to promote transcription of operably linked nucleotide sequences. Other embodiments relate to a 3? UTR or a terminator from a GmCAB2 gene that functions in plants to promote transcription of operably linked nucleotide sequences.
    Type: Application
    Filed: October 29, 2018
    Publication date: November 5, 2020
    Applicants: DOW AGROSCIENCES LLC, PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: Lyudmila Sidorenko, Cory M. Larsen, Geny Anthony, Shreedharan Sriram, Holly Jean Butler, Lynne E. Sims, Scott H. Diehn, Gilda M. Rauscher, Kevin G. Ripp, Knut Meyer
  • Publication number: 20200340005
    Abstract: Compositions and methods related to transgenic high oleic acid/ALS inhibitor-tolerant soybean plants are provided. Specifically, the present invention provides soybean plants having a DP-305423-1 event which imparts a high oleic acid phenotype and tolerance to at least one ALS-inhibiting herbicide. The soybean plant harboring the DP-305423-1 event comprises genomic/transgene junctions having at least the polynucleotide sequence of SEQ ID NO:8, 9, 14, 15, 20, 21, 83 or 84. The characterization of the genomic insertion site of the DP-305423-1 event provides for an enhanced breeding efficiency and enables the use of molecular markers to track the transgene insert in the breeding populations and progeny thereof. Various methods and compositions for the identification, detection, and use of the soybean DP-305423-1 events are provided.
    Type: Application
    Filed: July 13, 2020
    Publication date: October 29, 2020
    Applicant: E. I. DU PONT DE NEMOURS AND COMPANY
    Inventors: KENT BRINK, ROBERT F CRESSMAN, JR., ANTHONY J KINNEY, KNUT MEYER, KEVIN L STECCA, NATALIE N WEBER, CATHY XIAOYAN ZHONG
  • Publication number: 20200332314
    Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.
    Type: Application
    Filed: November 29, 2018
    Publication date: October 22, 2020
    Applicant: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: ALBERT L LU, KNUT MEYER, GILDA RAUSCHER, GUSUI WU
  • Patent number: 10745711
    Abstract: Compositions and methods related to transgenic high oleic acid/ALS inhibitor-tolerant soybean plants are provided. Specifically, the present invention provides soybean plants having a DP-305423-1 event which imparts a high oleic acid phenotype and tolerance to at least one ALS-inhibiting herbicide. The soybean plant harboring the DP-305423-1 event comprises genomic/transgene junctions having at least the polynucleotide sequence of SEQ ID NO:8, 9, 14, 15, 20, 21, 83 or 84. The characterization of the genomic insertion site of the DP-305423-1 event provides for an enhanced breeding efficiency and enables the use of molecular markers to track the transgene insert in the breeding populations and progeny thereof. Various methods and compositions for the identification, detection, and use of the soybean DP-305423-1 events are provided.
    Type: Grant
    Filed: October 18, 2017
    Date of Patent: August 18, 2020
    Assignee: E. I. DU PONT DE NEMOURS AND COMPANY
    Inventors: Anthony J Kinney, Kent Brink, Robert F. Cressman, Jr., Knut Meyer, Kevin L. Stecca, Natalie N. Weber, Cathy Xiaoyan Zhong
  • Patent number: 10633666
    Abstract: Transgenic oilseeds having increased total fatty acid content of at least 10% and altered fatty acid profiles when compared to the total fatty acid content of null segregant oilseeds are described. Novel DGAT genes are used to achieve the increase in seed storage lipids.
    Type: Grant
    Filed: June 11, 2018
    Date of Patent: April 28, 2020
    Assignee: E I DU PONT DE NEMOURS AND COMPANY
    Inventors: Keith Roesler, Ericka Bermudez, Howard Glenn Damude, Changjiang Li, Knut Meyer, Bo Shen, Mitchell C. Tarczynski