Abstract: A needle injection catheter includes a delivery tube that slidably surrounds a hypotube that has at least three hollow needle portions connected to and extending outwardly at its distal end. The needle portions are formed of resilient material and curve outwardly from the delivery tube. The ends of the needle portions are shaped to penetrate tissue when the hypotube is urged out of the delivery tube. A first sensor is located adjacent the distal end of the delivery tube and a second sensor is located adjacent the end of the needle portion. The sensors are electrically connected to first and second notification devices located adjacent a first end of the delivery tube. Radiopaque markers are affixed to the delivery tube to locate the tip using an enhanced imaging system. The markers are sized, shaped, positioned and of different densities to locate the tip both axially and radially within body structures.