Abstract: A liquid medicine container includes a container body having threaded neck with an opening formed thereon for the entry of a liquid medicine into the container body. A seal member is fit into the opening to seal it. A through hole is formed on the seal member to be in fluid communication with the interior of the container body. The neck has a circumferential flange formed thereon with two recesses formed on the flange. The neck also has a groove formed thereon and extending in a direction substantially normal to the threading of the neck from a point close the circumferential flange, crossing the neck threading, to a point close to the opening. A cap member has an open end with segmented threading formed therein to be engageable with the neck threading for tightening the cap member on the neck wherein the edge of the open end of the cap member is in contact engagement with the flange and two bosses formed on the edge of the open end of the cap member received within the recesses formed on the flange.