Patents by Inventor Ko-Hua Chen
Ko-Hua Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230031385Abstract: A corneal storage composition is disclosed. The composition comprises a buffered, balanced, nutrient and electrolyte aqueous solution; ?-PGA; and ferulic acid, in amounts effective to maintain cell integrity and viability of the corneal tissue for a period of greater than 14 days.Type: ApplicationFiled: July 20, 2021Publication date: February 2, 2023Inventors: Feng-Huei LIN, Yu-Chun CHEN, Wen-Yu SU, Yen-Hsien LEE, Ko-Hua CHEN
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Patent number: 9457000Abstract: Ophthalmic irrigating solutions are disclosed. The ophthalmic irrigating solution comprises: a) ?-polyglutamic acid (?-PGA) and/or salt thereof in an amount effective to increase the viscosity of the irrigating solution, and b) an ophthalmically acceptable aqueous vehicle for the ?-PGA and/or salt thereof. Also disclosed is a method of irrigating ocular tissues of a patient, in which the method comprises introducing to the ocular tissues of the patient an ophthalmic irrigating solution comprising ?-PGA) and/or salt thereof in an amount sufficient to irrigate the ocular tissues of the patient.Type: GrantFiled: June 16, 2013Date of Patent: October 4, 2016Assignee: NATIONAL HEALTH RESEARCH INSTITUTESInventors: Yu-Chun Chen, Wen-Yu Su, Yen-Hsien Lee, Ko-Hua Chen, Feng-Huei Lin
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Patent number: 8975651Abstract: An LED package includes a lens, an LED chip securely received and engaged in the lens, and a base with an electrode assembly thereon. A bottom surface of the LED chip is bare. The lens is mounted on the base and the bottom surface of the LED chip electrically and mechanically connects with the electrode assembly.Type: GrantFiled: April 17, 2013Date of Patent: March 10, 2015Assignee: Hon Hai Precision Industry Co., Ltd.Inventors: Yun-Yu Chou, Ko-Hua Chen
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Publication number: 20140314893Abstract: A mold assembly for manufacturing light guide plates of different sizes without being dismantled includes a male mold with base, a number of pairs of molding blocks and driving blocks, together with two bolts, and an injecting block. The pairs of molding and driving blocks, and the driving block and two bolts are received in the male mold base. The driving block is movably connected to the molding block by the two bolts. A position of the molding block relative to the driving block is adjusted by screwing at least one of the two bolts. An injecting block is positioned in the male mold base and surrounds a male mold chamber with the molding block.Type: ApplicationFiled: August 30, 2013Publication date: October 23, 2014Applicant: HON HAI PRECISION INDUSTRY CO., LTD.Inventors: YUN-YU CHOU, KO-HUA CHEN
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Publication number: 20140314900Abstract: A mold assembly for fabricating an optical fiber connector includes a male mold and a first sliding block. The male mold includes a base, a first locating flange, and a second locating flange. The first locating flange and the second locating flange are spaced apart from each other. The first locating flange, the second locating flange, and the base cooperatively define a first receiving opening. A front surface of the first sliding block defines two first holes for forming two locating poles of the lens assembly. A shape and a size of the first sliding block respectively correspond to a shape and size of the first receiving opening to make the first sliding block be precisely located in the first receiving opening.Type: ApplicationFiled: October 24, 2013Publication date: October 23, 2014Applicant: HON HAI PRECISION INDUSTRY CO., LTD.Inventors: YUN-YU CHOU, KO-HUA CHEN
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Publication number: 20140209946Abstract: An LED package includes a lens, an LED chip securely received and engaged in the lens, and a base with an electrode assembly thereon. A bottom surface of the LED chip is bare. The lens is mounted on the base and the bottom surface of the LED chip electrically and mechanically connects with the electrode assembly.Type: ApplicationFiled: April 17, 2013Publication date: July 31, 2014Applicant: HON HAI PRECISION INDUSTRY CO., LTD.Inventors: YUN-YU CHOU, KO-HUA CHEN
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Publication number: 20130273186Abstract: Ophthalmic irrigating solutions are disclosed. The ophthalmic irrigating solution comprises: a) ?-polyglutamic acid (?-PGA) and/or salt thereof in an amount effective to increase the viscosity of the irrigating solution, and b) an ophthalmically acceptable aqueous vehicle for the ?-PGA and/or salt thereof. Also disclosed is a method of irrigating ocular tissues of a patient, in which the method comprises introducing to the ocular tissues of the patient an ophthalmic irrigating solution comprising ?-PGA) and/or salt thereof in an amount sufficient to irrigate the ocular tissues of the patient.Type: ApplicationFiled: June 16, 2013Publication date: October 17, 2013Inventors: Yu-Chun Chen, Wen-Yu Su, Yen-Hsien Lee, Ko-Hua Chen, Feng-Huei Lin
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Publication number: 20130139399Abstract: A measuring fixture is used with a slide caliper for measuring dimensions of workpiece; the measuring fixture includes a first measuring portion and a second measuring portion. The first measuring portion defines a plurality of first measuring grooves thereon. The second measuring portion defines a plurality of second measuring grooves thereon corresponding to the plurality of first measuring grooves respectively. The measuring fixture defines a receiving portion thereon between the first and the second measuring portions. A pair of measuring jaws of the slide caliper are capable of sliding and receiving in a first measuring groove and a corresponding second measuring groove respectively to measure linear dimension or size of workpiece received in the receiving portion.Type: ApplicationFiled: October 9, 2012Publication date: June 6, 2013Inventors: YUN-YU CHOU, KO-HUA CHEN
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Patent number: 8197849Abstract: A composition comprising a polymer that comprises oxidated hyaluronic acid cross-linked by a dihydrazide is disclosed. The polymer is a hydrogel exhibiting the following properties: a) transparent and colorless; and b) transforming from a liquid state into a gel-matrix at 37° C. These characteristics make it useful as a vitreous humor substitute.Type: GrantFiled: August 31, 2010Date of Patent: June 12, 2012Assignee: National Health Research InstitutesInventors: Feng-Huei Lin, Wen-Yu Su, Yu-Chun Chen, Ko-Hua Chen
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Publication number: 20110251137Abstract: Ophthalmic irrigating solutions are disclosed. The ophthalmic irrigating solution comprises: a) ?-polyglutamic acid (?-PGA) and/or salt thereof in an amount effective to increase the viscosity of the irrigating solution; and b) an ophthalmically acceptable aqueous vehicle for the ?-PGA and/or salt thereof. Also disclosed is a method of irrigating ocular tissues of a patient, in which the method comprises introducing to the ocular tissues of the patient an ophthalmic irrigating solution comprising ?-PGA) and/or salt thereof in an amount sufficient to irrigate the ocular tissues of the patient.Type: ApplicationFiled: April 6, 2011Publication date: October 13, 2011Applicant: NATIONAL HEALTH RESEARCH INSTITUTESInventors: Yu-Chun CHEN, Wen-Yu Su, Yen-Hsien Lee, Ko-Hua Chen, Feng-Huei Lin
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Publication number: 20110200676Abstract: A composition comprising a polymer that comprises oxidated hyaluronic acid cross-linked by a dihydrazide is disclosed. The polymer is a hydrogel exhibiting the following properties: a) transparent and colorless; and b) transforming from a liquid state into a gel-matrix at 37° C. These characteristics make it useful as a vitreous humor substitute.Type: ApplicationFiled: August 31, 2010Publication date: August 18, 2011Applicant: NATIONAL HEALTH RESEARCH INSTITUTESInventors: Feng-Huei LIN, Wen-Yu Su, Yu-Chun Chen, Ko-Hua Chen
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Publication number: 20080174733Abstract: A method of using infrared thermal imager to diagnose eye diseases including the dry eye syndromeuses an infrared thermal imager to take the surface image of the eyeball of the patient. Temperature variation at a specific position of the cornea of the eyeball is precisely measured in a unit time. An attenuation coefficient K of a temperature dropping curve and a temperature difference ?T are obtained from the temperature variation. Optimized curves of K and ?T are provided for the doctor to diagnose the patient's eye disease.Type: ApplicationFiled: January 18, 2007Publication date: July 24, 2008Applicant: UNITED INTEGRATED SERVICES CO., LTD.Inventors: David O. Chang, Kenny Hui-Hua Chiang, Ko-Hua Chen
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Patent number: 6548059Abstract: Disclosed is a method of stimulating adult corneal endothelial cell proliferation, which includes incubation of corneal endothelium to a mitogen-containing medium and then to an agent that interrupts cell-cell contacts in the adult corneal endothelial cells, and subsequently, as needed, further incubation in the mitogen-containing medium. The cell-cell contact-interrupting agent is preferably a calcium chelator.Type: GrantFiled: January 9, 2002Date of Patent: April 15, 2003Assignee: The Schepens Eye Research Institute, Inc.Inventors: Nancy C. Joyce, Ko-Hua Chen, Tadashi Senoo
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Patent number: 6541256Abstract: A human cell growth medium formulation for culturing human cells of neural crest origin, most preferably corneal endothelial cells, or for accelerating the growth and proliferation of human cells of neural crest origin is disclosed. The formulation for the nutrient medium of the invention includes nerve growth factor, preferably at a concentration of 1-100 ng/ml and most preferably 20 ng/ml. The growth medium formulation preferably also includes epidermal growth factor (preferably at a concentration of 1-200 ng/ml and most preferably 5 ng/ml).Type: GrantFiled: September 14, 2001Date of Patent: April 1, 2003Assignee: The Schepens Eye Research Institute, Inc.Inventors: Ko-Hua Chen, Nancy C. Joyce