Patents by Inventor Ko TSUTSUI

Ko TSUTSUI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for enhancing activity of laminin fragments as cell culture matrix
    Patent number: 10428311
    Abstract: The present invention provides a novel technique in a cell culture method using a cell culture vessel coated with a laminin fragment, which novel technique achieves cell culture as in the case of using a recommended coating concentration even when the coating concentration is lower than the recommended coating concentration. The present invention relates to a method for enhancing an activity for mammalian cultured cells of a laminin fragment or a variant thereof each having integrin binding activity.
    Type: Grant
    Filed: July 15, 2015
    Date of Patent: October 1, 2019
    Assignee: OSAKA UNIVERSITY
    Inventors: Kiyotoshi Sekiguchi, Ko Tsutsui
  • Cell culture vessel coated with laminin fragment in dry state
    Patent number: 10287541
    Abstract: Provided is a cell culture vessel characterized in that a surface to be in contact with cells is coated with a laminin fragment having integrin ?6?1 binding activity or a modified form thereof in a dry state, the laminin fragment being derived from at least one kind selected from laminin ?5?1?1 and laminin ?5?2?1, the cell culture vessel being any of the following: (1) a cell culture vessel of which a surface to be in contact with cells is coated only with a laminin fragment having integrin ?6?1 binding activity or a modified form thereof in a dry state; (2) a cell culture vessel of which a surface to be in contact with cells is coated with a laminin fragment having integrin ?6?1 binding activity or a modified form thereof in combination with a laminin fragment having no integrin ?6?1 binding activity in a dry state; and (3) a cell culture vessel of which a surface to be in contact with cells is coated with a laminin fragment having integrin ?6?1 binding activity or a modified form thereof in combinatio
    Type: Grant
    Filed: May 9, 2014
    Date of Patent: May 14, 2019
    Assignee: OSAKA UNIVERSITY
    Inventors: Kiyotoshi Sekiguchi, Ko Tsutsui
  • METHOD FOR ENHANCING ACTIVITY OF LAMININ FRAGMENTS AS CELL CULTURE MATRIX
    Publication number: 20170159020
    Abstract: The present invention provides a novel technique in a cell culture method using a cell culture vessel coated with a laminin fragment, which novel technique achieves cell culture as in the case of using a recommended coating concentration even when the coating concentration is lower than the recommended coating concentration. The present invention relates to a method for enhancing an activity for mammalian cultured cells of a laminin fragment or a variant thereof each having integrin binding activity.
    Type: Application
    Filed: July 15, 2015
    Publication date: June 8, 2017
    Applicant: OSAKA UNIVERSITY
    Inventors: Kiyotoshi SEKIGUCHI, Ko TSUTSUI
  • CELL CULTURE EQUIPMENT COATED WITH LAMININ FRAGMENTS IN DRY STATE
    Publication number: 20160137965
    Abstract: Provided is a cell culture vessel characterized in that a surface to be in contact with cells is coated with a laminin fragment having integrin ?6?1 binding activity or a modified form thereof in a dry state, the laminin fragment being derived from at least one kind selected from laminin ?5?1?1 and laminin ?5?2?1, the cell culture vessel being any of the following: (1) a cell culture vessel of which a surface to be in contact with cells is coated only with a laminin fragment having integrin ?6?1 binding activity or a modified form thereof in a dry state; (2) a cell culture vessel of which a surface to be in contact with cells is coated with a laminin fragment having integrin ?6?1 binding activity or a modified form thereof in combination with a laminin fragment having no integrin ?6?1 binding activity in a dry state; and (3) a cell culture vessel of which a surface to be in contact with cells is coated with a laminin fragment having integrin ?6?1 binding activity or a modified form thereof in combination
    Type: Application
    Filed: May 9, 2014
    Publication date: May 19, 2016
    Applicant: OSAKA UNIVERSITY
    Inventors: Kiyotoshi SEKIGUCHI, Ko TSUTSUI