Patents by Inventor Kock Fye Tam

Kock Fye Tam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Three-dimensional bioresorbable scaffolds for tissue engineering applications
    Patent number: 8071007
    Abstract: The invention relates to the use of Fused Deposition Modeling to construct three-dimensional (3D) bioresorbable scaffolds from bioresorbable polymers such as polycaprolactone (PCL), or from composites of bioresorbable polymers and ceramics, such as polycaprolactone/hydroxyapatite (PCL/HA). Incorporation of a bioresorbable ceramic to produce a hybrid/composite material support provides the desired degradation and resorption kinetics. Such a composite material improves the biocompatibility and hard tissue integration and allows for increased initial flash spread of serum proteins. The basic resorption products of the composite also avoids the formation of an unfavorable environment for hard tissue cells due to a decreased pH. The scaffolds have applications in tissue engineering, e.g., in tissue engineering bone and cartilage.
    Type: Grant
    Filed: April 20, 2004
    Date of Patent: December 6, 2011
    Assignee: Osteopore International Pte. Ltd.
    Inventors: Swee Hin Teoh, Dietmar Werner Hutmacher, Kim Cheng Tan, Kock Fye Tam, Iwan Zein
  • Three-dimensional bioresorbable scaffolds for tissue engineering applications
    Patent number: 7968026
    Abstract: The invention relates to the use of Fused Deposition Modeling to construct three-dimensional (3D) bioresorbable scaffolds from bioresorbable polymers such as polycaprolactone (PCL), or from composites of bioresorbable polymers and ceramics, such as polycaprolactone/hydroxyapatite (PCL/HA). Incorporation of a bioresorbable ceramic to produce a hybrid/composite material support provides the desired degradation and resorption kinetics. Such a composite material improves the biocompatibility and hard tissue integration and allows for increased initial flash spread of serum proteins. The basic resorption products of the composite also avoids the formation of an unfavorable environment for hard tissue cells due to a decreased pH. The scaffolds have applications in tissue engineering, e.g., in tissue engineering bone and cartilage.
    Type: Grant
    Filed: April 20, 2004
    Date of Patent: June 28, 2011
    Assignee: Osteopore International Ltd.
    Inventors: Swee Hin Teoh, Dietmar Werner Hutmacher, Kim Cheng Tan, Kock Fye Tam, Iwan Zein
  • Methods for fabricating a filament for use in tissue engineering
    Patent number: 6730252
    Abstract: The invention relates to the use of Fused Deposition Modeling to construct three-dimensional (3D) bioresorbable scaffolds from bioresorbable polymers such as polycaprolactone (PCL), or from composites of bioresorbable polymers and ceramics, such as polycaprolactone/hydroxyapatite (PCL/HA). Incorporation of a bioresorbable ceramic to produce a hybrid/composite material support provides the desired degradation and resorption kinetics. Such a composite material improves the biocompatibility and hard tissue integration and allows for increased initial flash spread of serum proteins. The basic resorption products of the composite also avoids the formation of an unfavorable environment for hard tissue cells due to a decreased pH. The scaffolds have applications in tissue engineering, e.g., in tissue engineering bone and cartilage.
    Type: Grant
    Filed: September 20, 2001
    Date of Patent: May 4, 2004
    Inventors: Swee Hin Teoh, Dietmar Werner Hutmacher, Kim Cheng Tan, Kock Fye Tam, Iwan Zein