Patents by Inventor Koen Visscher

Koen Visscher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250143836
    Abstract: Systems and methods for imaging using a microscope system comprising removeable or replaceable component parts. Such systems and methods employ semi-kinetic coupling for easy, tool-free attachment of the microscope system to a baseplate. Discussed systems and methods may include simultaneous imaging and stimulation using a microscope system. The microscope system can have a relatively small size compared to an average microscope system.
    Type: Application
    Filed: January 8, 2025
    Publication date: May 8, 2025
    Inventors: Kelvin KAO, David PIGNATELLI, Mark O. TRULSON, Alice STAMATAKIS, Koen VISSCHER
  • Patent number: 12251272
    Abstract: Provided herein are systems and methods for imaging using a microscope system comprising removeable or replaceable component parts. Such systems and methods employ semi-kinetic coupling for easy, tool-free attachment of the microscope system to a baseplate. Systems and methods provided herein may comprise simultaneous imaging and stimulation using a microscope system. The microscope system can have a relatively small size compared to an average microscope system.
    Type: Grant
    Filed: June 17, 2022
    Date of Patent: March 18, 2025
    Assignee: INSCOPIX, INC.
    Inventors: Kelvin Kao, David Pignatelli, Mark O. Trulson, Alice Stamatakis, Koen Visscher
  • Publication number: 20250017683
    Abstract: Systems and methods configured for simultaneous imaging and stimulation using a microscope system. The microscope system can have a relatively small size compared to an average microscope system. The microscope can comprise in part an imaging light source and a stimulation light source. Light from the imaging light source and the stimulation light source can be spectrally separated to reduce cross talk between the stimulation light and the imaging light.
    Type: Application
    Filed: October 1, 2024
    Publication date: January 16, 2025
    Applicant: Inscopix, Inc.
    Inventors: Mark O. TRULSON, Alice STAMATAKIS, Koen VISSCHER
  • Publication number: 20240385423
    Abstract: Systems and methods for multi-color imaging using a microscope system. The microscope system can have a relatively small size as compared to an average microscope system. The microscope system can include various components configured to reduce or eliminate image artifacts such as chromatic aberrations and/or noise from stray light that can occur during multi-color imaging. The components can be configured to reduce or eliminate the image artifacts, and/or noise without substantially changing the size of the microscope system.
    Type: Application
    Filed: July 26, 2024
    Publication date: November 21, 2024
    Applicant: Inscopix, Inc.
    Inventors: Mark TRULSON, Koen VISSCHER, Kevin NEWMAN
  • Publication number: 20240361543
    Abstract: A system including a device configured to be partially inside of a target object (and to remain affixed to such object substantially irremovably and in an unchanged orientation with respect to such object at least on a time-scale comparable to term of life or use of the target object itself) to provide chronic access to an internal object location from an outside location and communication with such location along multiple communication channels that are spatially separate and substantially immovable with respect to one another while remaining moveable together and synchronously with the object. Delivery of electromagnetic energy and a material stimulus along the first and second communication channels is carried out such as to necessarily maintain unchanged mutual spatial positioning and orientation between the channels regardless of whether the channels are being used or not and regardless of whether the target object—together with these channels—is spatially repositioned.
    Type: Application
    Filed: April 22, 2024
    Publication date: October 31, 2024
    Inventors: Swathy Sampath Kumar, David Cheng, Jonathan Nassi, Koen Visscher
  • Patent number: 12109074
    Abstract: Systems and methods configured for simultaneous imaging and stimulation using a microscope system. The microscope system can have a relatively small size compared to an average microscope system. The microscope can comprise in part an imaging light source and a stimulation light source. Light from the imaging light source and the stimulation light source can be spectrally separated to reduce cross talk between the stimulation light and the imaging light.
    Type: Grant
    Filed: May 17, 2023
    Date of Patent: October 8, 2024
    Assignee: INSCOPIX, INC.
    Inventors: Mark O. Trulson, Alice Stamatakis, Koen Visscher
  • Patent number: 12099175
    Abstract: An adapter configured to be optically coupled to a plurality of microscopes and including a) a first microscope interface configured to optically couple a first microscope to an optical element in optical communication with an optical probe; b) a second microscope interface configured to optically couple a second microscope to the optical element in optical communication with the optical probe; and c) an optical arrangement configured to direct light collected from a sample with the aid of the optical probe to (1) the first microscope and second microscope simultaneously, or (2) the first microscope or second microscope selectively.
    Type: Grant
    Filed: November 25, 2020
    Date of Patent: September 24, 2024
    Assignee: INSCOPIX, INC.
    Inventors: Koen Visscher, Shung Chieh, Arash Tajik
  • Patent number: 12066618
    Abstract: Systems and methods for multi-color imaging using a microscope system. The microscope system can have a relatively small size as compared to an average microscope system. The microscope system can include various components configured to reduce or eliminate image artifacts such as chromatic aberrations and/or noise from stray light that can occur during multi-color imaging. The components can be configured to reduce or eliminate the image artifacts, and/or noise without substantially changing the size of the microscope system.
    Type: Grant
    Filed: July 6, 2023
    Date of Patent: August 20, 2024
    Assignee: INSCOPIX, INC.
    Inventors: Mark Trulson, Koen Visscher, Kevin Newman
  • Publication number: 20240207011
    Abstract: An adapter configured to be optically coupled to a plurality of microscopes and having (i) a first microscope interface configured to optically couple a first microscope system to an optical element that is in optical communication with an optical probe to provide first imaging data of a sample, and (ii) a second microscope interface configured to optically couple a second microscope system to the optical element to provide second imaging data of the sample. An optical imaging apparatus and method utilizing such adapter.
    Type: Application
    Filed: March 5, 2024
    Publication date: June 27, 2024
    Applicant: Inscopix, Inc.
    Inventors: Koen VISSCHER, Pei Sabrina XU, Shay NEUFELD
  • Patent number: 11960072
    Abstract: An adapter configured to be optically coupled to a plurality of microscopes. The adapter includes a) a first microscope interface configured to optically couple a first microscope to an optical element in optical communication with an optical probe; b) a second microscope interface configured to optically couple a second microscope to the optical element in optical communication with the optical probe; and c) an optical arrangement configured to direct light collected from a sample with aid of the optical probe to (1) the first microscope and second microscope simultaneously, or (2) the first microscope or second microscope selectively.
    Type: Grant
    Filed: September 21, 2021
    Date of Patent: April 16, 2024
    Assignee: INSCOPIX, INC.
    Inventors: Koen Visscher, Pei Sabrina Xu, Shay Neufeld
  • Publication number: 20240115344
    Abstract: An adapter configured to be optically coupled to a plurality of microscopes and having (i) a first microscope interface configured to optically couple a first microscope system to an optical element that is in optical communication with an optical probe to provide first imaging data of a sample, and (ii) a second microscope interface configured to optically couple a second microscope system to the optical element to provide second imaging data of the sample. An optical imaging apparatus and method utilizing such adapter.
    Type: Application
    Filed: December 18, 2023
    Publication date: April 11, 2024
    Inventors: Koen VISSCHER, Pei Sabrina XU, Shay NEUFELD
  • Publication number: 20230359011
    Abstract: Systems and methods for multi-color imaging using a microscope system. The microscope system can have a relatively small size as compared to an average microscope system. The microscope system can include various components configured to reduce or eliminate image artifacts such as chromatic aberrations and/or noise from stray light that can occur during multi-color imaging. The components can be configured to reduce or eliminate the image artifacts, and/or noise without substantially changing the size of the microscope system.
    Type: Application
    Filed: July 6, 2023
    Publication date: November 9, 2023
    Applicant: Inscopix, Inc.
    Inventors: Mark TRULSON, Koen VISSCHER, Kevin NEWMAN
  • Publication number: 20230285107
    Abstract: Systems and methods configured for simultaneous imaging and stimulation using a microscope system. The microscope system can have a relatively small size compared to an average microscope system. The microscope can comprise in part an imaging light source and a stimulation light source. Light from the imaging light source and the stimulation light source can be spectrally separated to reduce cross talk between the stimulation light and the imaging light.
    Type: Application
    Filed: May 17, 2023
    Publication date: September 14, 2023
    Applicant: Inscopix, Inc.
    Inventors: Mark O. TRULSON, Alice STAMATAKIS, Koen VISSCHER
  • Patent number: 11733501
    Abstract: Provided herein are systems and methods for multi-color imaging using a microscope system. The microscope system can have a relatively small size compared to an average microscope system. The microscope system can comprise various components configured to reduce or eliminate image artifacts such as chromatic aberrations and/or noise from stray light that can occur during multi-color imaging. The components can be configured to reduce or eliminate the image artifacts, and/or noise without substantially changing the size of the microscope system.
    Type: Grant
    Filed: December 15, 2020
    Date of Patent: August 22, 2023
    Assignee: INSCOPIX INC.
    Inventors: Mark Trulson, Koen Visscher, Kevin E. Newman
  • Patent number: 11690696
    Abstract: Provided herein are systems and methods for simultaneous imaging and stimulation using a microscope system. The microscope system can have a relatively small size compared to an average microscope system. The microscope can comprise in part an imaging light source and a stimulation light source. Light from the imaging light source and the stimulation light source can be spectrally separated to reduce cross talk between the stimulation light and the imaging light.
    Type: Grant
    Filed: September 24, 2021
    Date of Patent: July 4, 2023
    Assignee: INSCOPIX, INC.
    Inventors: Mark O. Trulson, Alice Stamatakis, Koen Visscher
  • Publication number: 20220387127
    Abstract: Provided herein are systems and methods for imaging using a microscope system comprising removeable or replaceable component parts. Such systems and methods employ semi-kinetic coupling for easy, tool-free attachment of the microscope system to a baseplate. Systems and methods provided herein may comprise simultaneous imaging and stimulation using a microscope system. The microscope system can have a relatively small size compared to an average microscope system.
    Type: Application
    Filed: June 17, 2022
    Publication date: December 8, 2022
    Inventors: Kelvin KAO, David PIGNATELLI, Mark O. TRULSON, Alice STAMATAKIS, Koen VISSCHER
  • Publication number: 20220104907
    Abstract: Provided herein are systems and methods for simultaneous imaging and stimulation using a microscope system. The microscope system can have a relatively small size compared to an average microscope system. The microscope can comprise in part an imaging light source and a stimulation light source. Light from the imaging light source and the stimulation light source can be spectrally separated to reduce cross talk between the stimulation light and the imaging light.
    Type: Application
    Filed: September 24, 2021
    Publication date: April 7, 2022
    Inventors: Mark O. TRULSON, Alice STAMATAKIS, Koen VISSCHER
  • Publication number: 20220099954
    Abstract: Disclosed herein are adapters configured to be optically coupled to a plurality of microscopes, said adapter comprising: a) a first microscope interface configured to optically couple a first microscope to an optical element in optical communication with an optical probe; b) a second microscope interface configured to optically couple a second microscope to the optical element in optical communication with the optical probe; and c) an optical arrangement configured to direct light collected from a sample with aid of the optical probe to (1) the first microscope and second microscope simultaneously, or (2) the first microscope or second microscope selectively.
    Type: Application
    Filed: September 21, 2021
    Publication date: March 31, 2022
    Inventors: Koen Visscher, Pei Sabrina Xu, Shay Neufeld
  • Patent number: 11197735
    Abstract: Provided herein are systems and methods for simultaneous imaging and stimulation using a microscope system. The microscope system can have a relatively small size compared to an average microscope system. The microscope can comprise in part an imaging light source and a stimulation light source. Light from the imaging light source and the stimulation light source can be spectrally separated to reduce cross talk between the stimulation light and the imaging light.
    Type: Grant
    Filed: April 17, 2020
    Date of Patent: December 14, 2021
    Assignee: Inscopix, Inc.
    Inventors: Mark O. Trulson, Alice Stamatakis, Koen Visscher
  • Publication number: 20210247603
    Abstract: Provided herein are systems and methods for multi-color imaging using a microscope system. The microscope system can have a relatively small size compared to an average microscope system. The microscope system can comprise various components configured to reduce or eliminate image artifacts such as chromatic aberrations and/or noise from stray light that can occur during multi-color imaging. The components can be configured to reduce or eliminate the image artifacts, and/or noise without substantially changing the size of the microscope system.
    Type: Application
    Filed: December 15, 2020
    Publication date: August 12, 2021
    Inventors: Mark TRULSON, Koen VISSCHER, Kevin E. NEWMAN