Patents by Inventor Koenraad A. Dekker

Koenraad A. Dekker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Quinolone compounds for the treatment of disorders caused by helicobacter pylori
    Patent number: 5942619
    Abstract: This invention provides processes for producing quinolone compounds which comprise cultivating Amycoa sp. FERM BP-4785, and then isolating quinolone compounds from the fermentation broth. The compounds produced by these processes include compounds of formula (I) wherein R.sup.1 is H, R.sup.2 is (a) and R.sup.3 is CH.sub.3 ; R.sup.1 is CH.sub.3, R.sup.2 is (a) and R.sup.3 is CH.sub.3 ; or R.sup.1 is CH.sub.3, R.sup.2 is (b) and R.sup.3 is CH.sub.3 ; and the like. The present invention also relates to a pharmaceutical composition comprising the same, which is useful in the treatment of diseases, disorders and adverse conditions caused by Helicobacter pylori and is particularly useful in the treatment of gastroduodenal disorders, diseases and adverse conditions caused thereby.
    Type: Grant
    Filed: April 24, 1998
    Date of Patent: August 24, 1999
    Assignee: Pfizer Inc.
    Inventors: Koenraad A. Dekker, Liang H. Huang, Taisuke Inagaki, Nakao Kojima, Yasuhiro Kojima, Yuji Yamauchi
  • Phthalide compounds and their production process
    Patent number: 5861518
    Abstract: This invention provides processes for producing phthalide compounds which comprise cultivating Phanerochaete avelutina FERM BP-4787 and then isolating phthalide compounds from the fermentation broth.
    Type: Grant
    Filed: October 31, 1997
    Date of Patent: January 19, 1999
    Inventors: Koenraad A. Dekker, Yuji Yamauchi, Taisuke Inagaki, Shinichi Sakemi, Nakao Kojima