Patents by Inventor Kohei Akazawa
Kohei Akazawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20180258038Abstract: The present invention provides a pyrrolidine compound of General Formula (1) or a salt thereof, wherein R101 and R102 are each independently a phenyl group or a pyridyl group, the phenyl group or the pyridyl group may have one or more substituents selected from halogen atoms and lower alkyl groups optionally substituted with one or more halogen atoms, etc. The pyrrolidine compound or a salt thereof of the present invention is usable to produce a pharmaceutical preparation having a wider therapeutic spectrum and being capable of exhibiting sufficient therapeutic effects after short-term administration.Type: ApplicationFiled: May 9, 2018Publication date: September 13, 2018Applicant: OTSUKA PHARMACEUTICAL CO., LTD.Inventors: Muneaki KURIMURA, Shinichi TAIRA, Takahiro TOMOYASU, Nobuaki ITO, Kuninori TAI, Noriaki TAKEMURA, Takayuki MATSUZAKI, Yasuhiro MENJO, Shin MIYAMURA, Yohji SAKURAI, Akihito WATANABE, Yasuyo SAKATA, Takumi MASUMOTO, Kohei AKAZAWA, Haruhiko SUGINO, Naoki AMADA, Satoshi OHASHI, Tomoichi SHINOHARA, Hirofumi SASAKI, Chisako MORITA, Junko YAMASHITA, Satoko NAKAJIMA
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Patent number: 10000450Abstract: The present invention provides a pyrrolidine compound of General Formula (1) or a salt thereof, wherein R101 and R102 are each independently a phenyl group or a pyridyl group, the phenyl group or the pyridyl group may have one or more substituents selected from halogen atoms and lower alkyl groups optionally substituted with one or more halogen atoms, etc. The pyrrolidine compound or a salt thereof of the present invention is usable to produce a pharmaceutical preparation having a wider therapeutic spectrum and being capable of exhibiting sufficient therapeutic effects after short-term administration.Type: GrantFiled: February 16, 2017Date of Patent: June 19, 2018Assignee: OTSUKA PHARMACEUTICAL CO., LTD.Inventors: Muneaki Kurimura, Shinichi Taira, Takahiro Tomoyasu, Nobuaki Ito, Kuninori Tai, Noriaki Takemura, Takayuki Matsuzaki, Yasuhiro Menjo, Shin Miyamura, Yohji Sakurai, Akihito Watanabe, Yasuyo Sakata, Takumi Masumoto, Kohei Akazawa, Haruhiko Sugino, Naoki Amada, Satoshi Ohashi, Tomoichi Shinohara, Hirofumi Sasaki, Chisako Morita, Junko Yamashita, Satoko Nakajima
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Publication number: 20170166524Abstract: The present invention provides a pyrrolidine compound of General Formula (1) or a salt thereof, wherein R101 and R102 are each independently a phenyl group or a pyridyl group, the phenyl group or the pyridyl group may have one or more substituents selected from halogen atoms and lower alkyl groups optionally substituted with one or more halogen atoms, etc. The pyrrolidine compound or a salt thereof of the present invention is usable to produce a pharmaceutical preparation having a wider therapeutic spectrum and being capable of exhibiting sufficient therapeutic effects after short-term administration.Type: ApplicationFiled: February 16, 2017Publication date: June 15, 2017Applicant: OTSUKA PHARMACEUTICAL CO., LTD.Inventors: Muneaki KURIMURA, Shinichi TAIRA, Takahiro TOMOYASU, Nobuaki ITO, Kuninori TAI, Noriaki TAKEMURA, Takayuki MATSUZAKI, Yasuhiro MENJO, Shin MIYAMURA, Yohji SAKURAI, Akihito WATANABE, Yasuyo SAKATA, Takumi MASUMOTO, Kohei AKAZAWA, Haruhiko SUGINO, Naoki AMADA, Satoshi OHASHI, Tomoichi SHINOHARA, Hirofumi SASAKI, Chisako MORITA, Junko YAMASHITA, Satoko NAKAJIMA
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Patent number: 9611214Abstract: The present invention provides a pyrrolidine compound of General Formula (1) or a salt thereof, wherein R101 and R102 are each independently a phenyl group or a pyridyl group, the phenyl group or the pyridyl group may have one or more substituents selected from halogen atoms and lower alkyl groups optionally substituted with one or more halogen atoms, etc. The pyrrolidine compound or a salt thereof of the present invention is usable to produce a pharmaceutical preparation having a wider therapeutic spectrum and being capable of exhibiting sufficient therapeutic effects after short-term administration.Type: GrantFiled: June 10, 2014Date of Patent: April 4, 2017Assignee: OTSUKA PHARMACEUTICAL CO., LTD.Inventors: Muneaki Kurimura, Shinichi Taira, Takahiro Tomoyasu, Nobuaki Ito, Kuninori Tai, Noriaki Takemura, Takayuki Matsuzaki, Yasuhiro Menjo, Shin Miyamura, Yohji Sakurai, Akihito Watanabe, Yasuyo Sakata, Takumi Masumoto, Kohei Akazawa, Haruhiko Sugino, Naoki Amada, Satoshi Ohashi, Tomoichi Shinohara, Hirofumi Sasaki, Chisako Morita, Junko Yamashita, Satoko Nakajima
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Patent number: 9066469Abstract: A riding lawn mower includes: a delivery passage for delivering cut grass from a housing to a receptacle; and a shutter mechanism provided on a lower portion of the delivery passage for switching the mower between a bagging mode in which cut grass is delivered from the housing to the receptacle and a mulching mode in which cut grass is discharged downward of the housing. The shutter mechanism includes a horizontal pivot shaft disposed on the lower portion of the delivery passage, and a shutter plate pivotable about the pivot shaft between a fully closed position where the shutter plate closes the delivery passage to place the mower in the mulching mode and a fully opened position where the shutter plate is laid down toward a discharge side of the delivery passage to place the mower in the bagging mode.Type: GrantFiled: September 11, 2013Date of Patent: June 30, 2015Assignee: HONDA MOTOR CO., LTD.Inventors: Tomokazu Kimura, Toshiro Uchida, Kohei Akazawa, Takahiro Yamamoto
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Patent number: 9003753Abstract: A lawn mower includes: a cutting blade provided in a housing; a cut grass receptacle provided rearward of the housing; and a chute connecting between the housing and the cut grass receptacle, grass cut by the cutting blade being delivered, by cut grass delivering air, to the cut grass receptacle via the chute. The cut grass receptacle has a bottom plate detachably attachable thereto, and the cut grass receptacle is constructed to allow the bottom plate detached from the receptacle to be accommodated within the receptacle.Type: GrantFiled: September 11, 2013Date of Patent: April 14, 2015Assignee: Honda Motor Co., Ltd.Inventors: Takahiro Yamamoto, Tomokazu Kimura, Kohei Akazawa
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Publication number: 20140288065Abstract: The present invention provides a pyrrolidine compound of General Formula (1) or a salt thereof, wherein R101 and R102 are each independently a phenyl group or a pyridyl group, the phenyl group or the pyridyl group may have one or more substituents selected from halogen atoms and lower alkyl groups optionally substituted with one or more halogen atoms, etc. The pyrrolidine compound or a salt thereof of the present invention is usable to produce a pharmaceutical preparation having a wider therapeutic spectrum and being capable of exhibiting sufficient therapeutic effects after short-term administration.Type: ApplicationFiled: June 10, 2014Publication date: September 25, 2014Applicant: OTSUKA PHARMACEUTICAL CO., LTD.Inventors: Muneaki KURIMURA, Shinichi TAIRA, Takahiro TOMOYASU, Nobuaki ITO, Kuninori TAI, Noriaki TAKEMURA, Takayuki MATSUZAKI, Yasuhiro MENJO, Shin MIYAMURA, Yohji SAKURAI, Akihito WATANABE, Yasuyo SAKATA, Takumi MASUMOTO, Kohei AKAZAWA, Haruhiko SUGINO, Naoki AMADA, Satoshi OHASHI, Tomoichi SHINOHARA, Hirofumi SASAKI, Chisako MORITA, Junko YAMASHITA, Satoko NAKAJIMA
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Patent number: 8815871Abstract: The present invention provides a pyrrolidine compound of General Formula (1) or a salt thereof, wherein R101 and R102 are each independently a phenyl group or a pyridyl group, the phenyl group or the pyridyl group may have one or more substituents selected from halogen atoms and lower alkyl groups optionally substituted with one or more halogen atoms, etc. The pyrrolidine compound or a salt thereof of the present invention is usable to produce a pharmaceutical preparation having a wider therapeutic spectrum and being capable of exhibiting sufficient therapeutic effects after short-term administration.Type: GrantFiled: March 11, 2013Date of Patent: August 26, 2014Assignee: Otsuka Pharmaceutical Co., Ltd.Inventors: Muneaki Kurimura, Shinichi Taira, Takahiro Tomoyasu, Nobuaki Ito, Kuninori Tai, Noriaki Takemura, Takayuki Matsuzaki, Yasuhiro Menjo, Shin Miyamura, Yohji Sakurai, Akihito Watanabe, Yasuyo Sakata, Takumi Masumoto, Kohei Akazawa, Haruhiko Sugino, Naoki Amada, Satoshi Ohashi, Tomoichi Shinohara, Hirofumi Sasaki, Chisako Morita, Junko Yamashita, Satoko Nakajima
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Publication number: 20140075899Abstract: A lawn mower includes: a cutting blade provided in a housing; a cut grass receptacle provided rearward of the housing; and a chute connecting between the housing and the cut grass receptacle, grass cut by the cutting blade being delivered, by cut grass delivering air, to the cut grass receptacle via the chute. The cut grass receptacle has a bottom plate detachably attachable thereto, and the cut grass receptacle is constructed to allow the bottom plate detached from the receptacle to be accommodated within the receptacle.Type: ApplicationFiled: September 11, 2013Publication date: March 20, 2014Inventors: Takahiro Yamamoto, Tomokazu Kimura, Kohei Akazawa
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Publication number: 20140075901Abstract: A riding lawn mower includes: a delivery passage for delivering cut grass from a housing to a receptacle; and a shutter mechanism provided on a lower portion of the delivery passage for switching the mower between a bagging mode in which cut grass is delivered from the housing to the receptacle and a mulching mode in which cut grass is discharged downward of the housing. The shutter mechanism includes a horizontal pivot shaft disposed on the lower portion of the delivery passage, and a shutter plate pivotable about the pivot shaft between a fully closed position where the shutter plate closes the delivery passage to place the mower in the mulching mode and a fully opened position where the shutter plate is laid down toward a discharge side of the delivery passage to place the mower in the bagging mode.Type: ApplicationFiled: September 11, 2013Publication date: March 20, 2014Applicant: HONDA MOTOR CO., LTD.Inventors: Tomokazu Kimura, Toshiro Uchida, Kohei Akazawa, Takahiro Yamamoto
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Patent number: 8420623Abstract: The present invention provides a pyrrolidine compound of General Formula (1) or a salt thereof, wherein R101 and R102 are each independently a phenyl group or a pyridyl group, the phenyl group or the pyridyl group may have one or more substituents selected from halogen atoms and lower alkyl groups optionally substituted with one or more halogen atoms, etc. The pyrrolidine compound or a salt thereof of the present invention is usable to produce a pharmaceutical preparation having a wider therapeutic spectrum and being capable of exhibiting sufficient therapeutic effects after short-term administration.Type: GrantFiled: November 17, 2011Date of Patent: April 16, 2013Assignee: Otsuka Pharmaceutical Co., Ltd.Inventors: Muneaki Kurimura, Shinichi Taira, Takahiro Tomoyasu, Nobuaki Ito, Kuninori Tai, Noriaki Takemura, Takayuki Matsuzaki, Yasuhiro Menjo, Shin Miyamura, Yohji Sakurai, Akihito Watanabe, Yasuyo Sakata, Takumi Masumoto, Kohei Akazawa, Haruhiko Sugino, Naoki Amada, Satoshi Ohashi, Tomoichi Shinohara, Hirofumi Sasaki, Chisako Morita, Junko Yamashita, Satoko Nakajima
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Publication number: 20120065162Abstract: The present invention provides a pyrrolidine compound of General Formula (1) or a salt thereof, wherein R101 and R102 are each independently a phenyl group or a pyridyl group, the phenyl group or the pyridyl group may have one or more substituents selected from halogen atoms and lower alkyl groups optionally substituted with one or more halogen atoms, etc. The pyrrolidine compound or a salt thereof of the present invention is usable to produce a pharmaceutical preparation having a wider therapeutic spectrum and being capable of exhibiting sufficient therapeutic effects after short-term administration.Type: ApplicationFiled: November 17, 2011Publication date: March 15, 2012Applicant: OTSUKA PHARMACEUTICAL CO., LTD.Inventors: Muneaki KURIMURA, Shinichi TAIRA, Takahiro TOMOYASU, Nobuaki ITO, Kuninori TAI, Noriaki TAKEMURA, Takayuki MATSUZAKI, Yasuhiro MENJO, Shin MIYAMURA, Yohji SAKURAI, Akihito WATANABE, Yasuyo SAKATA, Takumi MASUMOTO, Kohei AKAZAWA, Haruhiko SUGINO, Naoki AMADA, Satoshi OHASHI, Tomoichi SHINOHARA, Hirofumi SASAKI, Chisako MORITA, Junko YAMASHITA, Satoko NAKAJIMA
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Patent number: 8084442Abstract: The present invention provides a pyrrolidine compound of General Formula (1) or a salt thereof, wherein R101 and R102 are each independently a phenyl group or a pyridyl group, the phenyl group or the pyridyl group may have one or more substituents selected from halogen atoms and lower alkyl groups optionally substituted with one or more halogen atoms, etc. The pyrrolidine compound or a salt thereof of the present invention is usable to produce a pharmaceutical preparation having a wider therapeutic spectrum and being capable of exhibiting sufficient therapeutic effects after short-term administration.Type: GrantFiled: May 12, 2006Date of Patent: December 27, 2011Assignee: Otsuka Pharmaceutical Co., Ltd.Inventors: Muneaki Kurimura, Shinichi Taira, Takahiro Tomoyasu, Nobuaki Ito, Kuninori Tai, Noriaki Takemura, Takayuki Matsuzaki, Yasuhiro Menjo, Shin Miyamura, Yohji Sakurai, Akihito Watanabe, Yasuyo Sakata, Takumi Masumoto, Kohei Akazawa, Haruhiko Sugino, Naoki Amada, Satoshi Ohashi, Tomoichi Shinohara, Hirofumi Sasaki, Chisako Morita, Junko Yamashita, Satoko Nakajima
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Patent number: 7845442Abstract: A handle structure of a walk-behind working machine includes: a handle having left and right raised portions extending upward from a handle frame and a cross portion interconnecting the left and right raised portions; and a main clutch lever shiftable from a clutch-OFF position to a clutch-ON position by being pivoted into pressed abutment against the cross portion. The main clutch lever is constructed in such a manner that, when the main clutch lever is in abutment against the cross portion, a space for allowing a human operator to grip the left and right raised portions is secured between the left and right raised portions and the main clutch lever.Type: GrantFiled: November 20, 2008Date of Patent: December 7, 2010Assignee: Honda Motor Co., Ltd.Inventors: Kohei Akazawa, Takayuki Sato, Kazuyoshi Miyahara
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Patent number: 7760963Abstract: A method employing a statistic means to test whether or not luminance signals around a point of interest are distributed according to the same probability distribution with respect to luminance signals of respective pixels constituting the image; determining a range where the same probability distribution can be regarded as being satisfied, estimating the true luminance value of the point of interest by using the luminance data of the range. Especially when the image signals are faint to such an extent that the intensity of the luminance signal is based on the Poisson distribution, it is effective to perform a smoothing processing for each of the probability distributions of the signals and the noises by a test of a uniformity of the Poisson distribution, enabling a clear and denoised image to be obtained.Type: GrantFiled: December 7, 2005Date of Patent: July 20, 2010Assignee: Niigata UniversityInventors: Takayuki Matsuto, Kohei Akazawa, Shin-ichi Toyabe, Tatsuo Ushiki
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Publication number: 20090127009Abstract: A handle structure of a walk-behind working machine includes: a handle having left and right raised portions extending upward from a handle frame and a cross portion interconnecting the left and right raised portions; and a main clutch lever shiftable from a clutch-OFF position to a clutch-ON position by being pivoted into pressed abutment against the cross portion. The main clutch lever is constructed in such a manner that, when the main clutch lever is in abutment against the cross portion, a space for allowing a human operator to grip the left and right raised portions is secured between the left and right raised portions and the main clutch lever.Type: ApplicationFiled: November 20, 2008Publication date: May 21, 2009Applicant: HONDA MOTOR CO., LTD.Inventors: Kohei Akazawa, Takayuki Sato, Kazuyoshi Miyahara
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Publication number: 20090088406Abstract: The present invention provides a pyrrolidine compound of General Formula (1) or a salt thereof, wherein R101 and R102 are each independently a phenyl group or a pyridyl group, the phenyl group or the pyridyl group may have one or more substituents selected from halogen atoms and lower alkyl groups optionally substituted with one or more halogen atoms, etc. The pyrrolidine compound or a salt thereof of the present invention is usable to produce a pharmaceutical preparation having a wider therapeutic spectrum and being capable of exhibiting sufficient therapeutic effects after short-term administration.Type: ApplicationFiled: May 12, 2006Publication date: April 2, 2009Inventors: Muneaki Kurimura, Shinichi Taira, Takahiro Tomoyasu, Nobuaki Ito, Kuninori Tai, Noriaki Takemura, Takayuki Matsuzaki, Yasuhiro Menjo, Shin Miyamura, Yohji Sakurai, Akihito Watanabe, Yasuyo Sakata, Takumi Masumoto, Kohei Akazawa, Haruhiko Sugino, Naoki Amada, Satoshi Ohashi, Tomoichi Shinohara, Hirofumi Sasaki, Chisako Morita, Junko Yamashita, Satoko Nakajima
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Publication number: 20080292208Abstract: A method employing a statistic means to test whether or not luminance signals around a point of interest are distributed according to the same probability distribution with respect to luminance signals of respective pixels constituting the image; determining a range where the same probability distribution can be regarded as being satisfied, estimating the true luminance value of the point of interest by using the luminance data of the range. Especially when the image signals are faint to such an extent that the intensity of the luminance signal is based on the Poisson distribution, it is effective to perform a smoothing processing for each of the probability distributions of the signals and the noises by a test of a uniformity of the Poisson distribution, enabling a clear and denoised image to be obtained.Type: ApplicationFiled: December 7, 2005Publication date: November 27, 2008Applicant: Niigata UniversityInventors: Takayuki Matsuto, Kohei Akazawa, Shin-ichi Toyabe, Tatsuo Ushiki