Abstract: The purpose of the present invention is to provide a novel stereoselective method for preparing a cyclic dinucleotide derivative and a production intermediate therefor, which can be used for an antibody-immunostimulant conjugate. Also provided is a method for producing a cyclic dinucleotide-linker and an antibody-immunostimulant conjugate while using the above production method. Further provided is a method for preparing a cyclic dinucleotide derivative, the method including the step of subjecting a compound (I) and a compound (IV) to stereoselective condensation using an optically active phosphitylating agent (Rc-II) or (Sc-II).

Abstract: A capacitor disposed inside a multilayer substrate that includes a conductive pattern on a surface thereof and an anode portion having a first conductive metal member and a porous portion disposed on a surface of the first conductive metal member, a cathode portion, and a dielectric layer disposed between the anode portion and the cathode portion. Moreover, the anode portion is led out to a surface side of the multilayer substrate by a connection electrode including an alloy layer containing a metal forming the first conductive metal member and a conductive layer disposed on the alloy layer, and in which the connection electrode is connected to the conductive pattern formed on the surface of the multilayer substrate.

Abstract: A speed reducing mechanism according to the present invention includes: a speed reducing unit for decelerating input rotation; an accelerating unit for accelerating rotation output from the speed reducing unit; and a brake unit for applying a braking force for braking the accelerating unit.

Abstract: A control system comprises a mobile object control unit for controlling a mobile object; an update control unit for controlling reception of an update program of the mobile object control unit from a server and controlling update of the mobile object control unit by the program; an acquisition unit for acquiring reception information indicating a communication manner for receiving from the server for each program; and a communication control unit for controlling receiving the program from the server, based on the reception information, wherein the acquisition unit is for, when both a first update program and a second update program received after update by the first update program is executed have not been received, acquiring information about change of reception information of the first update program, and the communication control unit is for controlling receiving the first update program based on the information about change acquired by the acquisition unit.

Abstract: A connection state identification system includes an identification information addition means and an identification information acquisition means. When an inspection optical signal, which is an optical signal for inspection transmitted by a first optical communication device to a second optical communication device, is received by the second optical communication device over inter-optical communication device optical paths, which are the optical paths included in the undersea optical cable system between the optical communication devices, the identification information addition means adds, to an unassigned frequency band of the inspection optical signal, the unassigned frequency band being a frequency band other than a frequency band assigned to optical communication, identification information differing for each inter-optical communication device optical path through which the inspection optical signal passes.

Abstract: A drive device protection structure has a rotary electric machine, a gearbox connected the rotary electric machine, an undercover disposed underneath the drive device and a protecting plate provided to the undercover. The rotary electric machine has a rotary electric machine housing that has a rotary electric machine flange. The gearbox has a gearbox housing that has a gearbox flange. The rotary electric machine flange and the gearbox flange are connected together. The rotary electric machine flange and the gearbox flange are formed such that a lower surface of the gearbox flange is positioned lower than a lower surface of the rotary electric machine flange. The protecting plate is formed of a material more rigid than a material of the undercover. The protecting plate is provided beneath connecting part between the rotary electric machine flange and the gearbox flange so as to face the connecting part.

Abstract: In order to readily carry out communication between terminal stations, a submarine optical communication system includes a first terminal station including a first monitoring means for monitoring the signal quality of dummy light a first dummy light source that outputs dummy light to the second terminal station, and a first light transmitting means for transmitting an optical signal to the second terminal station, the optical signal including a first signal quality of the dummy light; and the second terminal station including a second dummy light source that outputs dummy light to the first monitoring means, a second monitoring means for monitoring the signal quality of the dummy light, and a light receiving means for receiving the optical signal.

Abstract: Crystals of the compound represented by formula (1), a method for the production thereof, and a method for producing an antibody-drug conjugate using the crystals.

Abstract: In a power conversion system, a control circuit has, as its operation modes: a first control mode in which control circuit controls a DC-DC converter at a first drive frequency; a second control mode in which control circuit controls DC-DC converter at a second drive frequency higher than first drive frequency; and a third control mode in which control circuit controls DC-DC converter at a third drive frequency higher than first drive frequency. Control circuit is configured to change operation mode from first control mode into second control mode when detector circuit detects a predetermined change in output voltage while control circuit is operating in first control mode. Control circuit controls DC-DC converter in third control mode in a process of changing, in response to detection of predetermined change, operation mode from first control mode into second control mode before starting to control DC-DC converter in second control mode.

Abstract: Aspects of the present disclosure describe estimating/measuring core-cladding concentricity error in optical fibers. In sharp contrast to the prior art, our inventive method is based on measuring a seemingly unrelated property of fibers called guided acoustic wave Brillouin scattering (GAWBS). As we shall show and describe, by analyzing this GAWBS property we advantageously determine what level of CCCE is exhibited by the optical fiber.

Abstract: Aspects of the present disclosure describe methods for reducing guided acoustic wave Brillouin (GAWBS) noise in an optical fiber that may be included in an optical communications system by reducing the polarization diffusion length of the fiber by increasing the birefringence of the optical fiber, the increased birefringence of the optical fiber being increased with respect to its average magnitude. Additionally, the polarization diffusion length is reduced by reducing the coherence length of birefringence of the optical fiber.

Abstract: Aspects of the present disclosure describe a three-way branching unit switch module having a small footprint suitable for application in an undersea application.

Abstract: A heating device includes: a temperature change unit that changes a temperature of a temperature change area; an induction unit that applies a stimulus to an induction area; and a controller, wherein the induction area is an area on skin surface, or an area that occupies a space that can be perspectively projected on the skin surface, the induction area is an area that does not overlap with the temperature change area, the induction unit applies at least one of a tactile stimulus and a visual stimulus to the induction area, the controller executes a first control for changing a temperature of a first temperature change area of the temperature change area and a second control for applying a stimulus to a first induction area of the induction area, and the second control is performed in accordance with the first control.

Abstract: In order to readily carry out communication between terminal stations, a submarine optical communication system includes a first terminal station including a first monitoring means for monitoring the signal quality of dummy light a first dummy light source that outputs dummy light to the second terminal station, and a first light transmitting means for transmitting an optical signal to the second terminal station, the optical signal including a first signal quality of the dummy light; and the second terminal station including a second dummy light source that outputs dummy light to the first monitoring means, a second monitoring means for monitoring the signal quality of the dummy light, and a light receiving means for receiving the optical signal.

Abstract: Earthquake detection via fiber sensing is provided using using a supervisory path of submarine cables wherein the supervisory system/path of a submarine optical cable conveys portion(s) of an optical signal back to an origin location periodically—i.e., at every repeater location. Advantageously, since it is known where a returning signal is coming from, a resolution equivalent to an undersea span length may be determined—which is sufficient for wide area disturbances such as earthquakes. The returned signal is sufficiently strong such that the signal-to-noise ratio of a returned/received signal is not limited by the ASE noise of the amplifiers. The returned signal is much larger as compared to a normal distributed acoustic sensing (DAS) return signal since the return signal according to aspects of the present disclosure is directed backward via an optical coupler/reflector/circulator having a much larger coupling ratio as compared to normal Rayleigh back scattering utilized in DAS.

Abstract: Aspects of the present disclosure describe a method for estimating mode field distribution in optical fibers from guided acoustic-wave Brillouin scattering wherein light for which the optical mode-field distribution is determined remains in the optical fibers and the distribution is made for light inside the fiber, and not at a fiber/air interface or other perturbation points to the fiber resulting in a more accurate representation of the optical mode-field distribution in the fiber. Since light is always in the fiber during the determination, no complicated fiber preparation steps or procedures are required and the mode-field distribution is determined as an average distribution along the length of the fiber under test.

Abstract: Aspects of the present disclosure describe methods for reducing guided acoustic wave Brillouin (GAWBS) noise in an optical fiber that may be included in an optical communications system by reducing the polarization diffusion length of the fiber by increasing the birefringence of the optical fiber, the increased birefringence of the optical fiber being increased with respect to its average magnitude. Additionally, the polarization diffusion length is reduced by reducing the coherence length of birefringence of the optical fiber.

Abstract: Aspects of the present disclosure are directed to systems, methods, and structures providing for the accurate measurement of guided acoustic-wave Brillouin scattering in optical fiber transmission systems and facilities.

Abstract: Aspects of the present disclosure describe estimating/measuring core-cladding concentricity error in optical fibers. In sharp contrast to the prior art, our inventive method is based on measuring a seemingly unrelated property of fibers called guided acoustic wave Brillouin scattering (GAWBS). As we shall show and describe, by analyzing this GAWBS property we advantageously determine what level of CCCE is exhibited by the optical fiber.

Abstract: In a wedge looseness diagnosis which is performed by striking wedges of a rotary electric machine, a variation of a wave form of a strike sound is reduced with respect to a variation of an amount of looseness of the wedges, and it is difficult that a slight difference of the amount of the looseness of the wedges is discriminated, so that the wedges are struck by a strike portion in a state where the wedges are pressed by a pressure portion which presses the wedges, and a strike sound at a high frequency is reduced, whereby an amount of a variation of magnitude of the strike sound is enlarged with respect to a valuation of the amount of the looseness of the wedges, and the amount of the looseness of the wedges is judged in accordance with the strike sound which is obtained by a strike sound measuring portion.