Abstract: Provided are a liposome composition which has a practically required long-term preservation stability, and which has a release rate of a drug on the order of several tens of hours due to releasability of a drug being able to be suitably controlled by rendering an inner water phase hyper-osmotic; and a method for producing the same. According to the present invention, it is possible to provide a liposome composition, including liposomes each of which has an inner water phase and an aqueous solution which constitutes an outer water phase and in which the liposomes are dispersed, in which the content of cholesterols is 10 mol % to 35 mol % with respect to the total amount of lipid components in the liposome composition, and each of the liposomes encapsulates a drug in a dissolved state, and an osmotic pressure of the inner water phase is 2-fold to 8-fold relative to the osmotic pressure of the outer water phase.

Abstract: Provided are a liposome composition in which an osmotic pressure of an inner water phase is 2-fold to 8-fold relative to the osmotic pressure of an outer water phase, and which encapsulates a water-soluble drug in a dissolved state, and also exhibits excellent preservation stability; and a method for producing the same. According to the present invention, it is possible to provide a liposome composition, including liposomes obtained from lipids dissolved and emulsified in an organic solvent, each of which has an inner water phase and an aqueous solution which constitutes an outer water phase and in which the liposomes are dispersed, in which each of the liposomes encapsulates a water-soluble drug in a dissolved state, and an osmotic pressure of the inner water phase is 2-fold to 8-fold relative to the osmotic pressure of the outer water phase; and a method for producing the same.

Abstract: Provided are a liposome composition which has a practically required long-term preservation stability, and which has a release rate of a drug on the order of several tens of hours due to releasability of a drug being able to be suitably controlled by rendering an inner water phase hyper-osmotic; and a method for producing the same. According to the present invention, it is possible to provide a liposome composition, including liposomes each of which has an inner water phase and an aqueous solution which constitutes an outer water phase and in which the liposomes are dispersed, in which each of the liposomes encapsulates a drug in a dissolved state, an osmotic pressure of the inner water phase is 2-fold to 8-fold relative to the osmotic pressure of the outer water phase, and a release rate of the drug from each of the liposomes is 10%/24 hr to 70%/24 hr in blood plasma at 37° C.; and a method for producing the same.

Abstract: In an arc welding control method for controlling welding in which a material of a base material is a galvanized steel sheet, a feed speed of a welding wire is alternately switched between a forward feed period and a reverse feed period, and a short circuit period and an arc period are repeated, during the arc period, a first arc period Ta1 during which a first arc current Ia1 is applied, a second arc period Ta2 during which a second arc current Ia2 is applied, and a third arc period Ta3 during which a third arc current Ia3 is applied are switched over time, and it is controlled so as to be Ia1>Ia2>Ia3. Constant voltage control is performed during the second arc period Ta2, and constant current control is performed during the first arc period Ta1.

Abstract: The purpose of the present invention is to reduce the amount of sputtering in a welding method wherein a welding wire feed rate is alternately switched between a forward feed period and a reverse feed period. Provided is an arc welding control method that switches a feed rate Fw for welding wire alternately between a forward feed period and a reverse feed period, repeats a short period and an arc period, and electrifies with a welding current Iw switched to a small current value in the latter half of the arc period, wherein a basic voltage setting value is set according to an average feed rate setting value, the error amplitude value for a voltage setting value and the basic voltage setting value is calculated, and the timing (current reduction time Td) for switching the welding current Iw to the small current value is varied on the basis of the average feed rate setting value and the error amplitude value.

Abstract: In an arc start control method for forward and reverse feed arc welding in which forward and reverse feed control of alternately switching a feed speed Fw of a welding wire between a forward feed period and a reverse feed period is performed to generate a short circuit period and an arc period to perform welding, at arc start, a pulse period Tp during which a pulse current is energized for a plurality of number of times is provided, and thereafter forward and reverse feed control is started from forward feed period of the welding wire. During the pulse period Tp, a forward feed speed Fp of the welding wire is set so that the arc period is continuous. In addition, the forward feed speed Fp is changed based on a time length of pulse period Tp and/or a value of a welding voltage Vw during pulse period Tp.

Abstract: Provided are a liposome composition which has a practically required long-term preservation stability, and which has a release rate of a drug on the order of several tens of hours due to releasability of a drug being able to be suitably controlled by rendering an inner water phase hyper-osmotic; and a method for producing the same. According to the present invention, it is possible to provide a liposome composition, including liposomes each of which has an inner water phase and an aqueous solution which constitutes an outer water phase and in which the liposomes are dispersed, in which the content of cholesterols is 10 mol % to 35 mol % with respect to the total amount of lipid components in the liposome composition, and each of the liposomes encapsulates a drug in a dissolved state, and an osmotic pressure of the inner water phase is 2-fold to 8-fold relative to the osmotic pressure of the outer water phase.

Abstract: An arc welding control method for controlling welding in which a material of a welding wire is aluminum or an aluminum alloy, and a feed speed Fw of the welding wire is alternately switched between a forward feed period and a reverse feed period to repeat a short circuit period and an arc period, a welding current Iw is controlled so that an average value of maximum values of the welding current Iw during the short circuit period is 150 A or less. A reverse feed peak value Wrp during the reverse feed period is set so that an average value of time lengths of the short circuit period is 7 ms or less. Accordingly, the current value can be reduced when the short circuit is released and the lengthening in the short circuit period can be prevented, so that the spatter generation amount can be reduced.

Abstract: A data processing apparatus processes moving image data that shows a vicinity of a vehicle and that is recorded while the vehicle is running. The data processing apparatus includes a controller configured to: acquire behavioral information on a specific behavior of the vehicle during an image capturing period of the moving image data; acquire object information on an object in the vicinity of the vehicle during the image capturing period of the moving image data; and determine a cause of the specific behavior of the vehicle based on the behavioral information and the object information.

Abstract: Provided are a liposome composition which has a practically required long-term preservation stability, and which has a release rate of a drug on the order of several tens of hours due to releasability of a drug being able to be suitably controlled by rendering an inner water phase hyper-osmotic; and a method for producing the same. According to the present invention, it is possible to provide a liposome composition, including liposomes each of which has an inner water phase and an aqueous solution which constitutes an outer water phase and in which the liposomes are dispersed, in which the content of cholesterols is 10 mol % to 35 mol % with respect to the total amount of lipid components in the liposome composition, and each of the liposomes encapsulates a drug in a dissolved state, and an osmotic pressure of the inner water phase is 2-fold to 8-fold relative to the osmotic pressure of the outer water phase.

Abstract: A method is provided for controlling arc welding including forward and reverse feeding periods alternately switched. By the method, a set of a short circuit period and an arc period is repeated, and the arc welding is controlled such that the reverse feeding period shifts to the forward feeding period when an arc occurs during the reverse feeding period, and that the forward feeding period shifts to the reverse feeding period when a short circuit occurs between the welding wire and the object during the forward feeding period. The reverse feeding period includes a reverse feeding deceleration period having a time length that is adjusted in accordance with the time length of the short circuit period.

Abstract: A light absorbing member includes a ceramic composite having a plurality of first ceramic particles exhibiting positive resistance temperature characteristics in a first ceramics having an open porosity of 5% or lower.

Abstract: A drive recorder sends to a server a moving image file showing a situation of surroundings of vehicle in a moment at which large acceleration occurred. The server determines, based on moving image file, whether or not to prohibit from being overwritten moving image file showing surroundings of vehicle in a moment at which an event occurred. Based on a determination result determined by the server, the drive recorder prohibits from being overwritten an image data set showing the moment 1) at which the event occurred or 2) optionally before and/or after the event occurred including the moment at which the event occurred. Thus, the drive recorder can surely prohibit the image data set to be prohibited from being overwritten. Moreover, it is possible to effectively use a storage area of a memory by allowing overwriting image data set that does not necessarily need to be prohibited from being overwritten.

Abstract: This pharmaceutical composition contains a hvdroxamic acid derivative, or a salt thereof, and a solubilizer, said hydroxamic acid derivative being selected from among (2S)-2-((4-((4-((1S)-1,2-dihydroxyethyl)phenyl)ethynyl)benzoyl)(methyl)amino)-N-hydroxy-N?,2- dimethylmalonamide, (2S)-2-((4((4-((1R)-1,2-dihydroxyethyl)phenyl)ethynyl)benzoyl)(methyl)amino)-N-hydroxy-N?,2-dimethylmalonamide, and (2S)-N-hydroxy-2-((4-((4-((1S)-1-hydroxy-2-methoxyethyl)phenyl)ethynyl)benzoyl)(methyl)amino)-N?,2-dimethylmalonamide. The pharmaceutical composition demonstrates strong antibacterial activity, has excellent solubility in water, and is useful as a drug.

Abstract: This pharmaceutical composition contains a hydroxamic acid derivative, or a salt thereof, and a solubilizer, said hydroxamic acid derivative being selected from among (2S)-2-((4-((4-((1S)-1,2-dihydroxyethyl)phenyl)ethynyl)benzoyl)(methyl)amino)-N-hydroxy-N?,2-dimethylmalonamide, 2S)-2-((4-((4-((1R)-1,2-dihydroxyethyl)phenyl)ethynyl)benzoyl)(methyl)amino)-N-hydroxy-N?,2-dimethylmalonamide, and (2S)-N-hydroxy-2-((4-((4-((1S)-1-hydroxy-2-methoxyethyl)phenyl)ethynyl)benzoyl)(methyl)amino)-N?,2-dimethylmalonamide. The pharmaceutical composition demonstrates strong antibacterial activity, has excellent solubility in water, and is useful as a drug.

Abstract: Provided is a method for producing a liposome having safety and stability. According to the present invention, it is possible to provide a method for producing a liposome, including a step of mixing an oil phase with at least one lipid dissolved in an organic solvent and a water phase and stirring an aqueous solution containing the lipids, and a step of evaporating the organic solvent from the aqueous solution containing the liposomes obtained in the stirring step, in which the organic solvent is a mixed solvent of a water-soluble organic solvent and an ester-based organic solvent.

Abstract: An information presentation device according to embodiment includes acquisition unit, generation unit, and output unit. Acquisition unit acquires information of driving history with respect to driving position in driving lane of vehicle, where information is generated by on-vehicle device based on image captured by imaging device that is mounted on vehicle. Generation unit generates information of graph that indicates transition of positional change of vehicle in driving lane, based on information of driving history acquired by acquisition unit. Output unit outputs information of graph generated by generation unit to display device. Acquisition unit acquires information of driving history that includes distances of right and left edge of driving lane with respect to vehicle. Generation unit generates information of graph based on difference between distances of right and left edge of driving lane with respect to vehicle that is included in information of driving history acquired by acquisition unit.

Abstract: A first detector is provided with a cuff adapted to be placed on an upper arm of a subject to detect noninvasive blood pressure of the subject. At least one second detector is adapted to be placed on a part of the subject to detect at least one vital sign of the subject. A single main body is detachably provided on the cuff while being connected with the first detector and the at least one second detector. A display is provided on the main body and operable to display the non-invasive blood pressure and the at least one vital sign as measurement data. A transmitter is provided in the main body and operable to transmit the measurement data to a receiver placed in a remote location.

Abstract: Provided are a liposome composition in which an osmotic pressure of an inner water phase is 2-fold to 8-fold relative to the osmotic pressure of an outer water phase, and which encapsulates a water-soluble drug in a dissolved state, and also exhibits excellent preservation stability; and a method for producing the same. According to the present invention, it is possible to provide a liposome composition, including liposomes obtained from lipids dissolved and emulsified in an organic solvent, each of which has an inner water phase and an aqueous solution which constitutes an outer water phase and in which the liposomes are dispersed, in which each of the liposomes encapsulates a water-soluble drug in a dissolved state, and an osmotic pressure of the inner water phase is 2-fold to 8-fold relative to the osmotic pressure of the outer water phase; and a method for producing the same.

Abstract: A data reproducing apparatus that reproduces moving image data that is captured while a vehicle is traveling includes a controller configured to: derive a stoppable distance that the vehicle requires to come to a stop based on a speed of the vehicle obtained while the vehicle was traveling during an image-capturing time period in which the moving image data was captured; derive an inter-vehicle distance between the vehicle and a preceding vehicle located ahead of the vehicle during the image-capturing time period in which the moving image data was captured; and superimpose, on an object image generated from the moving image data, a first mark which shows a position corresponding to the stoppable distance and a second mark which shows a position corresponding to the inter-vehicle distance.