Abstract: The present inventors have found that by cultivating insect cells, into which the Cas3 gene has been introduced, at relatively low temperatures, it is possible to efficiently express recombinant Cas3 proteins with maintained activity, and by purifying the soluble fractions of these cells, it is possible to collect active forms of the recombinant Cas3 proteins in high purity and high yield.

Abstract: A sample holder includes a base comprising a support structure and a printed circuit board (PCB) in contact with the base. The PCB includes: a dielectric; a front-surface ground (GND) formed on a front surface of the dielectric; a back-surface GND formed on a back surface of the dielectric; a through hole penetrating from the front-surface GND to the back-surface GND, the through hole in which a chip is disposed, and a conductor that electrically connects the front-surface GND and the back-surface GND on an end face of the through hole. At least a part of the base below the through hole has a cavity. The support structure that supports a surface of the chip and is electrically connected to the base. The support structure is disposed in the cavity.

Abstract: A piezoelectric speaker (10) includes: a piezoelectric film (35); a fixing face (17) for fixing the piezoelectric film (35) to a support; and an interposed layer (40) disposed between the piezoelectric film (35) and the fixing face (17). The interposed layer (40) has a holding degree of 5×108 N/m3 or less.

Abstract: A tactile and proximity sensor includes a light source, a light receiving section, and a cover. The light source emits light. The light receiving section receives light and generates a signal providing a result of the received light. The cover includes an elastic body that deforms under external force and that covers the light source and the light receiving section. The cover includes a reflective section that reflects light between the light source and the light receiving section and a transmission section that allows light to pass through in a first direction from the light source and that allows light to pass through in a second direction from the light receiving section.

Abstract: According to one embodiment, the information processing device includes: a first state estimator configured to estimate a state of a target rechargeable battery based on: first data including a charge amount and voltage value of a rechargeable battery; information including a state of the rechargeable battery; and second data including a charge amount and voltage value of the rechargeable battery.

Abstract: A biological detection device includes a signal acquirer that acquires a signal including a heartbeat, an analyzer that performs a frequency analysis of the signal to generate a spectrogram, an integrated value calculator that integrates energy of a heartbeat frequency component, which is a frequency component corresponding to the heartbeat, among frequency components of the signal shown by the spectrogram and calculates an integrated value, a peak specifier that specifies peaks, which are maximum values, in the integrated value, a peak set generator that combines, among the peaks, a first peak and a second peak, which occurs in a later time than the first peak, and generates a peak set, and a selector that selects, from the peak set, a sequence having highest likelihood in a maximum likelihood estimation method.

Abstract: A battery device includes a battery pack, a circuit substrate which acquires battery information on the battery pack or controls charge and discharge of the battery pack, a switch including a first power element or a second power element, and a heat radiator. The switch is a device controlling input and output of electric power to and from the battery pack, and an exterior part of the switch is arranged away from the circuit substrate. The heat radiator is a member made of a material having thermal conductivity, and is in direct contact with or indirect contact via a heat conductor with the exterior part of the switch so that heat of the switch can be transferred.

Abstract: An acidic gas separation membrane sheet causes an acidic gas to selectively permeate therethrough. The acidic gas separation membrane sheet includes a first porous layer, a hydrophilic resin composition layer, and a second porous layer in this order. A second peel strength between the second porous layer and the hydrophilic resin composition layer is less than a first peel strength between the first porous layer and the hydrophilic resin composition layer. An average value of the second peel strength is within a range of greater than or equal to 5 N/m and less than or equal to 500 N/m.

Abstract: Provided are: an azepan derivative represented by general formula (I) and a pharmaceutically acceptable salt thereof (in the formula: R1 represents a hydrogen atom, a C1-6 alkyl group which may have a substituent, etc.; R2 and R3 are the same as or different from each other, and represent a hydrogen atom, a C1-6 alkyl group which may have a substituent, etc.; R4 and R5 are the same as or different from each other, and represent a hydrogen atom, a C1-6 alkyl group which may have a substituent, etc.; R6 represents a hydrogen atom, a C1-6 alkyl group which may have a substituent, etc.; R7 and R8 are the same as or different from each other, and represent a hydrogen atom, a C1-6 alkyl group which may have a substituent, etc.; R9 and R10 are the same as or different from each other, and represent a hydrogen atom, a C1-6 alkyl group which may have a substituent, etc.; R11 represents a hydrogen atom, a C1-6 alkyl group which may have a substituent, etc.

Abstract: A signal representing heartbeat behavior is accurately restored. The present signal restoration system includes: a signal acquirer configured to acquire a first heartbeat signal representing heartbeat behavior; a first band-pass filter configured to generate a first signal by performing first band-pass filter processing on the first heartbeat signal; an integral calculator configured to calculate an integral value by integrating frequency intensity of the heartbeat represented by the first signal; a second band-pass filter configured to generate a third signal by performing second band-pass filter processing on a second signal representing the integral value with respect to time; and a restored signal generator configured to generate a restored signal representing heartbeat behavior based on first data generated by dividing the third signal at intervals of a predetermined time.

Abstract: To acquire distance information with high accuracy with a simple configuration, and perform highly reliable positioning. A communication device includes a distance acquisition unit that acquires distance information calculated on the basis of a propagation channel characteristic, and an altitude acquisition unit that acquires altitude information.

Abstract: The present invention chiefly aims to provide a novel composition for controlling indigenous bacterial flora in the skin which can enhance or improve the diversity of bacterial species in the indigenous bacterial flora in the skin relative to the condition before treatment. The present invention can include, for example, a composition (e.g., an ointment, a liquid) for controlling the diversity of bacterial species in indigenous bacterial flora in the skin, comprising an effective amount of earthworm lipids extracted from a raw earthworm (Lumbricus rubellus), and a base. The composition of the present invention is useful, for example, as a raw material for skin care products and cosmetics.

Abstract: A display control unit (52) displays a screen for setting sample information on a display unit (8) for each sample placed in a sample placement section (20), and an input processing unit (53) receives information such as a culture name and seeding date and time information input by an operator via an operation unit (7), and stores the information in a storage unit (55). This file is transferred to a data processing unit (4) and stored in a sample information storage unit (40). After analyzing the respective samples in an LC-MS (3), a quantitative analysis unit (42) performs a quantitative analysis based on the obtained data, associates the analysis result with the sample information, and stores the data in an analysis result storage unit (43). As a result, the sample information and the analysis result of the respective samples in the preprocessing stage are associated with each other.

Abstract: To provide a novel T-type calcium channel blocker. A compound represented by the following General Formula (I), a tautomer or a stereoisomer of the compound, a pharmaceutically acceptable salt of the compound, or a solvate of the compound, the tautomer, the stereoisomer, or the salt is used as a T-type calcium channel blocker.

Abstract: An information processing unit includes: an attention module having an attention layer and a computation section and that is for a neural network including plural levels of layer, the attention layer being configured to compute an output feature corresponding to an input feature from a predetermined layer and based on a parameter; the computation section that multiplies the input feature by the output feature, and outputs a computed result to a layer at a next level; the first learning unit connected to the neural network and that learns the parameter in a state in which learning has been suspended at least for the predetermined layer and the next level layer; and the channel selection section that selects as a redundant channel a channel satisfying a predetermined relationship between the output feature and a predetermined threshold value.

Abstract: There is provided a neural network reduction device including: an input section configured to acquire a first neural network including a plurality of processing layers that includes at least one convolutional layer; a generation section configured to generate a third neural network in which at least one second neural network is connected as an additional layer to a stage subsequent to the convolutional layer included in the first neural network; a learning section configured to train the third neural network; a correction section configured to select, as a redundant channel, a channel whose feature value calculated on a basis of a weight parameter of the second neural network establishes a predetermined relationship with a predetermined threshold, delete the redundant channel from the convolutional layer, and correct a weight parameter of the convolutional layer after deletion of the redundant channel on a basis of at least a portion of the weight parameter of the second neural network; a relearning section c

Abstract: It is an object to improve the accuracy of detecting breathing. The present system for detecting breathing comprises: a transmission unit that transmits radio waves to a plurality of positions including a position at which a subject is present; a reception unit that receives reflected waves as a result of reflection of the radio waves; a phase fluctuation calculator that calculates phase fluctuation of the reflected waves; a generator that performs a Fourier transform on the phase fluctuation and generates a spectrogram indicating a relationship between a time at which the reflected waves are received and a frequency component included in the reflected waves; and a breathing rate estimator that estimates a breathing rate of the subject by outputting a probability that the subject takes breaths at a predetermined frequency for each frequency based on the spectrogram and calculating a weighted average of the frequency by using the probability as a weight.

Abstract: A medicament for treating or preventing pruritus is provided. For the medicament for treating or preventing pruritus, a compound having a blocking action on Cav3.2T-type calcium channels represented by General Formulas (I) to (VI), a tautomer of the compound, a stereoisomer of the compound, a pharmaceutically acceptable salt thereof, or a solvate thereof is used as an active ingredient.

Abstract: A video display apparatus includes a wireless communicator which receives a video stream from a tuner apparatus via wireless communication, a display which displays a video based on the video stream, an HDMI (registered trademark) connector connected to a source apparatus via an HDMI (registered trademark) cable, and a changer which changes a signal output from an HPD terminal to the source apparatus to a level Lo when the signal output from the HPD terminal is at a level Hi and the video based on the video stream is displayed on the display.